DOI: 10.5551/jat1994.3.81. Regulation of Triglyceride Metabolism by PPARs : Fibrates and Thiazolidinediones have Distinct Effects

Regulation of Triglyceride Metabolism by PPARs : Fibrates and Thiazolidinediones have Distinct Effects
10.5551/jat1994.3.81
Crossref journal-article
Japan Atherosclerosis Society
Journal of Atherosclerosis and Thrombosis (3489)
Bibliography
Auwerx, J., Schoonjans, K., Fruchart, J.-C., & Staels, B. (1996). Regulation of Triglyceride Metabolism by PPARsâ¯: Fibrates and Thiazolidinediones have Distinct Effects. Journal of Atherosclerosis and Thrombosis, 3(2), 81â89.
Authors 4
Johan Auwerx (first)
Kristina Schoonjans (additional)
Jean-Charles Fruchart (additional)
Bart Staels (additional)
References 71 Referenced 91
Dates
Type	When
Created	11 years, 5 months ago (March 20, 2014, 7:04 p.m.)
Deposited	3 years, 5 months ago (March 30, 2022, 1:25 p.m.)
Indexed	11 months, 3 weeks ago (Sept. 14, 2024, 11:54 a.m.)
Issued	29 years, 8 months ago (Jan. 1, 1996)
Published	29 years, 8 months ago (Jan. 1, 1996)
Published Print	29 years, 8 months ago (Jan. 1, 1996)
Funders 0
None
BibTeX
@article{Auwerx_1996, title={Regulation of Triglyceride Metabolism by PPARs : Fibrates and Thiazolidinediones have Distinct Effects}, volume={3}, ISSN={1880-3873}, url={http://dx.doi.org/10.5551/jat1994.3.81}, DOI={10.5551/jat1994.3.81}, number={2}, journal={Journal of Atherosclerosis and Thrombosis}, publisher={Japan Atherosclerosis Society}, author={Auwerx, Johan and Schoonjans, Kristina and Fruchart, Jean-Charles and Staels, Bart}, year={1996}, pages={81–89} }
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      "unstructured": "(1) Schoonjans K, Staels B, and Auwerx J : Role of the peroxisome proliferator activated receptor (PPAR) in mediating effects of fibrates and fatty acids on gene expression. J Lipid Res, 37 : 907-925, 1996",
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      "unstructured": "(2) Osumi T, Wen JK, and Hashimoto T : Two cis-acting regulatory elements in the peroxisome proliferatorresponsive element enhancer region of rat acyl-CoA oxidase gene. Biochem Biophys Res Commun, 175 : 866-871, 1991",
      "DOI": "10.1016/0006-291X(91)91645-S"
    },
    {
      "key": "3",
      "doi-asserted-by": "crossref",
      "unstructured": "(3) Tugwood JD, Isseman I, Anderson RG, Bundell KR, McPheat WL, and Green S : The mouse peroxisome proliferator activated receptor recognizes a response element in the 5' flanking sequence of the rat acyl CoA oxidase gene. EMBO J, 11 : 433-439, 1992",
      "DOI": "10.1002/j.1460-2075.1992.tb05072.x"
    },
    {
      "key": "4",
      "doi-asserted-by": "crossref",
      "unstructured": "(4) Isseman I and Green S : Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators. Nature, 347 : 645-650, 1990",
      "DOI": "10.1038/347645a0"
    },
    {
      "key": "5",
      "doi-asserted-by": "crossref",
      "unstructured": "(5) Dreyer C, Krey G, Keller H, Givel F, Helftenbein G, and Wahli W : Control of the peroxisomal fl-oxidation pathway by a novel family of nuclear hormone receptors. Cell, 68 : 879-887, 1992",
      "DOI": "10.1016/0092-8674(92)90031-7"
    },
    {
      "key": "6",
      "doi-asserted-by": "crossref",
      "unstructured": "(6) Gottlicher M, Widmark E, Li Q, and Gustafsson JA : Fatty acids activate chimera of the clofibric acid-activated receptor and the glucocorticoid receptor. Proc Natl Acad Sci USA, 89 : 4653-4657, 1992",
      "DOI": "10.1073/pnas.89.10.4653"
    },
    {
      "key": "7",
      "doi-asserted-by": "crossref",
      "unstructured": "(7) Schmidt A, Endo N, Rutledge SJ, Vogel R, Shinar D, and Rodan GA : Identification of a new member of the steroid hormone receptor superfamily that is activated by a peroxisome proliferator and fatty acids. Mol Endocrinol, 6 : 1634-1641, 1992",
      "DOI": "10.1210/mend.6.10.1333051"
    },
    {
      "key": "8",
      "doi-asserted-by": "crossref",
      "unstructured": "(8) Sher T, Yi HF, McBride W, and Gonzalez FJ : cDNA cloning, chromosomal mapping, and functional characterization of the human peroxisome proliferator activated receptor. Biochemistry, 32 : 5598-5604, 1993",
      "DOI": "10.1021/bi00072a015"
    },
    {
      "key": "9",
      "doi-asserted-by": "crossref",
      "unstructured": "(9) Zhu Y, Alvares K, Huang Q, Rao MS, and Reddy JK : Cloning of a new member of the peroxisome proliferator activated receptor gene family from mouse liver. J Biol Chem, 268 : 26817-26820, 1993",
      "DOI": "10.1016/S0021-9258(19)74184-2"
    },
    {
      "key": "10",
      "doi-asserted-by": "crossref",
      "unstructured": "(10) Kliewer SA, Forman BM, Blumberg B, Ong ES, Borgmeyer U, Mangelsdorf DJ, Umesono K, and Evans RM : Differential expression and activation of a family of murine peroxisome proliferator-activated receptors. Proc Natl Acad Sci USA, 91 : 7355-7359, 1994",
      "DOI": "10.1073/pnas.91.15.7355"
    },
    {
      "key": "11",
      "doi-asserted-by": "crossref",
      "unstructured": "(11) Tontonoz P, Hu E, Graves RA, Budavari Al, and Spiegelman BM : mPPAR &gamma;2 : Tissue-specific regulator of an adipocyte enhancer. Genes Dev, 8 : 1224-1234, 1994.",
      "DOI": "10.1101/gad.8.10.1224"
    },
    {
      "key": "12",
      "doi-asserted-by": "crossref",
      "unstructured": "(12) Aperlo C, Pognonec P, Saladin R, Auwerx J, and Boulukos K : Isolation and characterization of the hamster peroxisomal proliferator activated receptor hPPARy, a member of the nuclear hormone receptor superfamily.Gene, 162 : 297-302, 1995",
      "DOI": "10.1016/0378-1119(95)00196-D"
    },
    {
      "key": "13",
      "unstructured": "(13) Greene ME, Blumberg B, McBride OW, Yi HF, Kronquist K, Kwan K, Hsieh L, Greene G, and Nimer SD : Isolation of the human peroxisome proliferator activated receptor gamma cDNA : Expression in hematopoietic cells and chromosomal mapping. Gene Expr, 4 : 281-299, 1995."
    },
    {
      "key": "14",
      "doi-asserted-by": "crossref",
      "unstructured": "(14) Lambe KG and Tugwood JD : A human peroxisome-proliferator activated receptor-&gamma; is activated by inducers of adipogenesis, including thiazolidinedione drugs. Eur J Biochem, 239 : 1-7, 1996",
      "DOI": "10.1111/j.1432-1033.1996.0001u.x"
    },
    {
      "key": "15",
      "doi-asserted-by": "crossref",
      "unstructured": "(15) Zhang B, Marcus SL, Sajjadi FG, Alvares K, Reddy JK, Subramani S, Rachubinski RA, and Capone JP : Identification of a peroxisome proliferator-responsive element upstream of the gene encoding rat peroxisomal enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase. Proc Natl Acad Sci USA, 89 : 7541-7545, 1992",
      "DOI": "10.1073/pnas.89.16.7541"
    },
    {
      "key": "16",
      "doi-asserted-by": "crossref",
      "unstructured": "(16) Bardot O, Aldridge TC, Latruffe N, and Green S : PPARRXR heterodimer activates a peroxisome proliferator response element upstream of the bifunctional enzyme gene. Biochem Biophys Res Commun, 192 : 37-45, 1993",
      "DOI": "10.1006/bbrc.1993.1378"
    },
    {
      "key": "17",
      "doi-asserted-by": "crossref",
      "unstructured": "(17) Marcus SL, Miyata KS, Zhang B, Subramani S, Rachubinski RA, and Capone JP : Diverse peroxisome proliferator-activated receptors bind to the peroxisome proliferator-responsive element of the rat hydratase/dehy-drogenase and fatty acyl-CoA oxidase genes but differentially induce expression. Proc Nati Acad Sci USA, 90 : 5723-5727, 1993",
      "DOI": "10.1073/pnas.90.12.5723"
    },
    {
      "key": "18",
      "unstructured": "(18) Alvarez K, Fan C, Daddras SS, Yelandi AV, Rachubinski RA, Capone JP, Subramani S, lannaccone PM, Rao MS, and Reddy JK : An upstream region of the enoyl-Coenzyme A hydratase 3-hydroxyacyl-Coenzyme A dehydrogenase gene directs luciferase expression in liver in response to peroxisome proliferators in transgenic mice. Cancer Res, 54 : 2303-2306, 1994"
    },
    {
      "key": "19",
      "doi-asserted-by": "crossref",
      "unstructured": "(19) Muerhoff AS, Griffin KJ, and Johnson EF : The peroxisome proliferator activated receptor mediates the induction of CYP4A6, a cytochrome P450 fatty Acid w-hydroxylase, by clofibric acid. J Biol Chem, 267 : 19051-19053, 1992",
      "DOI": "10.1515/JBCPP.1992.3.S1.39"
    },
    {
      "key": "20",
      "doi-asserted-by": "crossref",
      "unstructured": "(20) Palmer CNA, Hsu M-H, Muerhoff AS, Griffin KJ, and Johnson EF : Interaction of the peroxisome proliferator-activated receptor a with the retinoid X receptor a unmasks a cryptic peroxisome proliferator response element that overlaps an ARP-1-binding site in the CYP4A6 promoter. J Biol Chem, 269 : 18083-18089, 1994",
      "DOI": "10.1016/S0021-9258(17)32420-1"
    },
    {
      "key": "21",
      "doi-asserted-by": "crossref",
      "unstructured": "(21) Rodriguez JC, Gil-Gomez G, Hegardt FG, and Haro D : Peroxisome proliferator activated receptor mediates induction of the mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase gene by fatty acids. J Biol Chem, 269 : 18767-18772, 1994",
      "DOI": "10.1016/S0021-9258(17)32234-2"
    },
    {
      "key": "22",
      "doi-asserted-by": "crossref",
      "unstructured": "(22) Gulick T, Cresci S, Caira T, Moore DD, and Kelly DP : The peroxisome proliferator-activated receptor regulates mitochondrial fatty acid oxidative enzyme gene expression. Proc Natl Acad Sci USA, 91 : 11012-11016, 1994",
      "DOI": "10.1073/pnas.91.23.11012"
    },
    {
      "key": "23",
      "doi-asserted-by": "crossref",
      "unstructured": "(23) Vu-Dac N, Schoonjans K, Laine B, Fruchart JC, Auwerx J, and Staels B : Negative regulation of the human apolipoprotein A-I promoter by fibrates can be attenuated by the interaction of the peroxisome proliferatoractivated receptor with its response element. J Biol Chem, 269 : 31012-31018, 1994",
      "DOI": "10.1016/S0021-9258(18)47383-8"
    },
    {
      "key": "24",
      "doi-asserted-by": "crossref",
      "unstructured": "(24) Vu-Dac N, Schoonjans K, Kosykh V, Dallongeville J, Fruchart J-C, Staels B, and Auwerx J : Fibrates increasehuman apolipoprotein A-II expression through activation of the peroxisome proliferator-activated receptor. J Clin Invest, 96 : 741-750, 1995",
      "DOI": "10.1172/JCI118118"
    },
    {
      "key": "25",
      "doi-asserted-by": "crossref",
      "unstructured": "(25) Schoonjans K, Peinado-Onsurbe J, Heyman R, Briggs M, Cayet D, Deeb S, Staels B, and Auwerx J : PPARy and PPARy activators direct a tissue-specific transcriptional response via a PPRE in the lipoprotein lipase gene. EMBO J, (in press), 1996",
      "DOI": "10.1002/j.1460-2075.1996.tb00918.x"
    },
    {
      "key": "26",
      "doi-asserted-by": "crossref",
      "unstructured": "(26) Schoonjans K, Watanabe M, Suzuki H, Mahfoudi A, Krey G, Wahli W, Grimaldi P, Staels B, Yamamoto T, and Auwerx J : Induction of the Acyl-Coenzyme A synthetase gene by fibrates and fatty acids is mediated by a peroxisome proliferator response element in the C promoter. J Biol Chem, 270 : 19269-19276, 1995",
      "DOI": "10.1074/jbc.270.33.19269"
    },
    {
      "key": "27",
      "doi-asserted-by": "crossref",
      "unstructured": "(27) Forman BM, Tontonoz P, Chen J, Brun RP, Spiegelman BM, and Evans RM : 15-Deoxy-&Delta;12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR&gamma;. Cell, 83 : 803-812, 1995",
      "DOI": "10.1016/0092-8674(95)90193-0"
    },
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      "key": "28",
      "doi-asserted-by": "crossref",
      "unstructured": "(28) Lehmann JM, Moore LB, Smith-Oliver TA, Wilkison WO, Willson TM, and Kliewer SA : An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor &gamma; (PPAR&gamma;). J Biol Chem, 270 : 12953-12956, 1995",
      "DOI": "10.1074/jbc.270.22.12953"
    },
    {
      "key": "29",
      "doi-asserted-by": "crossref",
      "unstructured": "(29) Kliewer SA, Lenhard JM, Willson TM, Patel I, Morris DC, and Lehman JM : A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor &gamma; and promotes adipocyte differentiation. Cell, 83 : 813-819, 1995.",
      "DOI": "10.1016/0092-8674(95)90194-9"
    },
    {
      "key": "30",
      "doi-asserted-by": "crossref",
      "unstructured": "(30) Yu K, Bayona W, Kallen CB, Harding HP, Ravera CP, McMahon G, Brown M, and Lazar MA : Differential activation of peroxisome proliferator-activated receptors by eicosanoids. J Biol Chem, 270 : 23975-23983, 1995",
      "DOI": "10.1074/jbc.270.41.23975"
    },
    {
      "key": "31",
      "doi-asserted-by": "crossref",
      "unstructured": "(31) Beck F, Plummer S, Senior PV, Byrne S, Green S, and Brammar WJ : The ontogeny of peroxisome-proliferator-activated receptor gene expression in the mouse and rat. Proc Royal Soc Lond [Biol], 247 : 83-87, 1992",
      "DOI": "10.1098/rspb.1992.0012"
    },
    {
      "key": "32",
      "doi-asserted-by": "crossref",
      "unstructured": "(32) Braissant 0, Foufelle F, Scotto C, Dauca M, and Wahli W : Differential expression of peroxisome proliferator-activated receptors : Tissue distribution of PPAR&alpha;, &beta; and &gamma; in the adult rat. Endocrinology, 137 : 354-366, 1995",
      "DOI": "10.1210/endo.137.1.8536636"
    },
    {
      "key": "33",
      "doi-asserted-by": "crossref",
      "unstructured": "(33) Zhu Y, Qi C, Korenberg JR, Chen X-N, Noya D, Rao MS, and Reddy JK : Structural organization of mouse peroxisome proliferator activated receptor &gamma; (mPPAR&gamma;) gene : Alternative promoter use and different splicing yield two mPPAR&gamma; isoforms. Proc Nati Acad Sci USA, 92 : 7921-7925, 1995",
      "DOI": "10.1073/pnas.92.17.7921"
    },
    {
      "key": "34",
      "doi-asserted-by": "crossref",
      "unstructured": "(34) Tontonoz P, Hu E, and Spiegelman BM : Stimulation of adipogenesis in fibroblasts by PPAR&gamma;2, a lipid-activated transcription factor. Cell, 79 : 1147-1156, 1994",
      "DOI": "10.1016/0092-8674(94)90006-X"
    },
    {
      "key": "35",
      "doi-asserted-by": "crossref",
      "unstructured": "(35) Brun RP, Tontonoz P, Forman BM, Ellis R, Chen J, Evans RM, and Spiegelman BM Differential activation of adipogenesis by multiple PPAR isoforms. Genes Dev, 10 : 974-984, 1996",
      "DOI": "10.1101/gad.10.8.974"
    },
    {
      "key": "36",
      "doi-asserted-by": "crossref",
      "unstructured": "(36) Tontonoz P, Hu E, Devine J, Beale EG, and Spiegelman BM : PPAR&gamma;2 regulates adipose expression of the phosphoenolpyruvate carboxykinase gene. Mol Cell Biol, 15 : 351-357, 1995",
      "DOI": "10.1128/MCB.15.1.351"
    },
    {
      "key": "37",
      "doi-asserted-by": "crossref",
      "unstructured": "(37) Gaillard D, Negrel R, Lagarde M, and Ailhaud G : Requirement and role of arachidonic acid in the differen-tiation of pre-adipose cells. Biochem J, 257 : 389-397, 1989",
      "DOI": "10.1042/bj2570389"
    },
    {
      "key": "38",
      "doi-asserted-by": "crossref",
      "unstructured": "(38) Staels B and Auwerx J : Perturbation of developmental gene expression in rat liver by fibric acid derivatives : Lipoprotein lipase and alpha-fetoprotein as models. Development, 115 : 1035-1043, 1992",
      "DOI": "10.1242/dev.115.4.1035"
    },
    {
      "key": "39",
      "doi-asserted-by": "crossref",
      "unstructured": "(39) Wang C-S, McConathy WJ, Kloer HU, and Alaupovic P : Modulation of lipoprotein lipase activity by apolipo-proteins. Effect of apolipoprotein C-III. J Clin Invest, 75 : 384-390, 1985",
      "DOI": "10.1172/JCI111711"
    },
    {
      "key": "40",
      "doi-asserted-by": "crossref",
      "unstructured": "(40) Ginsberg HN, Le N-A, Goldberg IJ, Gibson JC, Rubinstein A, Wang-Iverson P, Norum R, and Brown WV : Apolipo-protein B metabolism in subjects with deficiency of apolipoproteins C-III and A-I : Evidence that apolipo-protein C-III inhibits catabolism of triglyceride-rich lipo-proteins by lipoprotein lipase in vivo. J Clin Invest, 78 : 1287-1295, 1986",
      "DOI": "10.1172/JCI112713"
    },
    {
      "key": "41",
      "doi-asserted-by": "crossref",
      "unstructured": "(41) Windler E, Chao Y, and Havel RJ : Regulation of the hepatic uptake of triglyceride-rich lipoproteins in the rat. J Biol Chem, 255 : 8303-8307, 1980",
      "DOI": "10.1016/S0021-9258(19)70647-4"
    },
    {
      "key": "42",
      "doi-asserted-by": "crossref",
      "unstructured": "(42) Quarfordt SH, Michalopoulos G, and Schirmer B : The effect of human C apolipoproteins on the in vitro hepatic metabolism of triglyceride emulsions in the rat. J Biol Chem, 257 : 14642-14647, 1982",
      "DOI": "10.1016/S0021-9258(18)33329-5"
    },
    {
      "key": "43",
      "doi-asserted-by": "crossref",
      "unstructured": "(43) Choi SY and Cooper AD : A comparison of the roles of the low density lipoprotein (LDL) receptor and the LDL receptor-related protein a2-macroglobulin receptor in chylomicron remnant removal in the mouse in vivo. J Biol Chem, 268 : 15804-15811, 1993",
      "DOI": "10.1016/S0021-9258(18)82326-2"
    },
    {
      "key": "44",
      "doi-asserted-by": "crossref",
      "unstructured": "(44) Malmendier CL, Lontie J-F, Delcroix C, Dubois DY, Magot T, and De Roy L : Apolipoproteins C-II and C-III metabolism in hypertriglyceridemic patients. Effect of a drastic triglyceride reduction by combined diet restriction and fenofibrate administration. Atherosclerosis, 77 : 139-149, 1989",
      "DOI": "10.1016/0021-9150(89)90075-0"
    },
    {
      "key": "45",
      "doi-asserted-by": "crossref",
      "unstructured": "(45) Rees A, Shoulders CC, Stocks J, Galton DJ, and Baralle FE : DNA polymorphism adjacent to human apoprotein A-I gene : Relation to hypertriglyceridemia. Lancet, i : 444-446, 1983",
      "DOI": "10.1016/S0140-6736(83)91440-X"
    },
    {
      "key": "46",
      "doi-asserted-by": "crossref",
      "unstructured": "(46) Dammerman M, Sandkuijl LA, Halaas JL, Chung W, and Breslow JL : An apolipoprotein C-III haplotype protective against hypertriglyceridemia is specified by promoter and 3' untranslated region polymorphisms. Proc Natl Acad Sci USA, 90 : 4562-4566, 1993",
      "DOI": "10.1073/pnas.90.10.4562"
    },
    {
      "key": "47",
      "doi-asserted-by": "crossref",
      "unstructured": "(47) Ito Y, Azrolan N, O'Connell A, Walsh A, and Breslow JL : Hypertriglyceridemia as a result of human apo C-III gene expression in transgenic mice. Science, 249 : 790-793, 1990",
      "DOI": "10.1126/science.2167514"
    },
    {
      "key": "48",
      "doi-asserted-by": "crossref",
      "unstructured": "(48) de Silva HV, Lauer SJ, Wang J, Simonet WS, Weisgraber KH, Mahley RW, and Taylor JM : Overexpression of human apolipoprotein C-III in transgenic mice results in an accumulation of apolipoprotein B48 remnants that is corrected by excess apolipoprotein E. J Biol Chem, 269 : 2324-2335, 1994",
      "DOI": "10.1016/S0021-9258(17)42171-5"
    },
    {
      "key": "49",
      "doi-asserted-by": "crossref",
      "unstructured": "(49) Maeda N, Li H, Lee D, Oliver P, Quarfordt SH, and Osada J : Targetted disruption of the apolipoprotein C-III gene in mice results in hypertriglyceridemia and protection from postprandial hypertriglyceridemia. J Biol Chem, 269 : 23610-23616, 1994",
      "DOI": "10.1016/S0021-9258(17)31559-4"
    },
    {
      "key": "50",
      "doi-asserted-by": "crossref",
      "unstructured": "(50) Parra HJ, Arveiller D, Evans AE, Cambou JP, Amouyel P, Bingham A, McMaster D, Schaffer P, Douste-Blazy P, Luc G, Richard JL, Ducimetiere P, Fruchart JC, and Cambien F : A case-control study of lipoprotein particles in two poulations at contrasting risk for coronary heart disease : the ECTIM study. Arterioscler Thromb, 12 : 701-707, 1992",
      "DOI": "10.1161/01.ATV.12.6.701"
    },
    {
      "key": "51",
      "doi-asserted-by": "crossref",
      "unstructured": "(51) Auwerx J, Leroy P, and Schoonjans K : Lipoprotein lipase : Recent contributions from molecular biology. Crit Rev Clin Lab Sci, 29 : 243-268, 1992",
      "DOI": "10.3109/10408369209114602"
    },
    {
      "key": "52",
      "unstructured": "(52) Brunzell JD : Familial lipoprotein lipase deficiency and other causes of the chylomicronemia syndrome. In : The metabolic basis of inherited disease, 6th edition, Scriver CR, et al., ed by Scriver CR, et al., pp 1165-1180, McGraw-Hill, New York, 1989"
    },
    {
      "key": "53",
      "doi-asserted-by": "crossref",
      "unstructured": "(53) Babirak SP, Iverius PH, Fujimoto WY, and Brunzell JD : Detection and characterization of the heterozygote state for lipoprotein lipase deficiency. Arterioscler Thromb, 9 : 326-334, 1989",
      "DOI": "10.1161/01.ATV.9.3.326"
    },
    {
      "key": "54",
      "doi-asserted-by": "crossref",
      "unstructured": "(54) Miesenbock G, HolzI B, Foger B, Brandstatter E, Paulweber B, Sandhofer F, and Patsch JR : Heterozygous lipoprotein lipase deficiency due to a missense mutation as the cause of impaired triglyceride tolerance with multiple lipoprotein abnormalities. J Clin Invest, 91 : 448-455, 1993",
      "DOI": "10.1172/JCI116222"
    },
    {
      "key": "55",
      "doi-asserted-by": "crossref",
      "unstructured": "(55) Williams KJ, Petrie KA, Brocia RW, and Swenson TL : Lipoprotein lipase modulates net secretory output of apolipoprotein B in vitro. A possible pathophysiologic explanation for familial combined hyperlipidemia. J Clin Invest, 88 : 1300-1306, 1991",
      "DOI": "10.1172/JCI115434"
    },
    {
      "key": "56",
      "unstructured": "(56) Ikeda H, Taketomi S, Sugiyama Y, Shimura Y, Sohda T, Meguro K, and Fujita T : Effects of pioglitazone on glucose and lipid metabolism in normal and insulin resistant animals. Drug Res, 40 : 156-162, 1990"
    },
    {
      "key": "57",
      "doi-asserted-by": "crossref",
      "unstructured": "(57) Schonfeld G : The effects of fibrates on lipoprotein and hemostatic risk factors. Atherosclerosis, 111 : 161-174, 1994",
      "DOI": "10.1016/0021-9150(94)90090-6"
    },
    {
      "key": "58",
      "doi-asserted-by": "crossref",
      "unstructured": "(58) Staels B, Vu-Dac N, Kosykh V, Saladin R, Fruchart JC, Dallongeville J, and Auwerx J : Fibrates down-regulate apolipoprotein C-III expression independent of induction of peroxisomal Acyl Co-enzyme A oxidase. J Clin Invest, 95 : 705-712, 1995",
      "DOI": "10.1172/JCI117717"
    },
    {
      "key": "59",
      "doi-asserted-by": "crossref",
      "unstructured": "(59) Ladias JAA, Hadzopoulou-Cladaras M, Kardassis D, Cardot P, Cheng J, Zannis V, and Cladaras C : Transcriptional regulation of human apolipoprotein genes apoB, apoCIII, and apoAll by members of the steroid hormone receptor superfamily HNF-4, ARP-1, EAR-2, and EAR-3. J Biol Chem, 267 : 15849-15860, 1992",
      "DOI": "10.1016/S0021-9258(19)49613-0"
    },
    {
      "key": "60",
      "doi-asserted-by": "crossref",
      "unstructured": "(60) Mietus-Snyder M, Sladek FM, Ginsburg GS, Kuo CF, Ladias JAA, Darnell JEJ, and Karathanasis SK : Antagonism between apolipoprotein A-I regulatory protein 1, Ear3/COUP-TF, and hepatocyte nuclear factor 4 modulates apolipoprotein C-Ill gene expression in liver and intestinal cells. Mol Cell Biol, 12 : 1708-1718, 1992",
      "DOI": "10.1128/MCB.12.4.1708"
    },
    {
      "key": "61",
      "doi-asserted-by": "crossref",
      "unstructured": "(61) Hertz R, Bishara-Shieban J, and Bar-Tana J : Mode of action of peroxisome proliferators as hypolipidemic drugs, suppression of apolipoprotein C-III. J Biol Chem, 270 : 13470-13475, 1995",
      "DOI": "10.1074/jbc.270.22.13470"
    },
    {
      "key": "62",
      "doi-asserted-by": "crossref",
      "unstructured": "(62) Heller F and Harvengt C : Effects of clofibrate, bezafibrate, fenofibrate, and probucol on plasma lipolytic enzymes in normolipidaemic subjects. Eur J Clin Pharmacol, 23 : 57-63, 1983",
      "DOI": "10.1007/BF00544015"
    },
    {
      "key": "63",
      "unstructured": "(63) Sommariva D, Bonfiglioloi D, Pogliaghi I, Zanaboni L, and Balboni E : Effects of procetofen on serum lipids and lipoproteins and on post-heparin lipase activities in type II and in type IV hyperlipoproteinemic patients. Curr Ther Res, 34 : 907-915, 1983"
    },
    {
      "key": "64",
      "doi-asserted-by": "crossref",
      "unstructured": "(64) Gnasso A, Lehner B, Haberbosch W, Leiss O, von Bergman K, and Augustin J : Effect of gemfibrozil on lipids, apoproteins, and postheparin lipolytic activities in normolipidemic subjects. Metabolism, 35 : 387-393, 1986",
      "DOI": "10.1016/0026-0495(86)90125-3"
    },
    {
      "key": "65",
      "doi-asserted-by": "crossref",
      "unstructured": "(65) Weisweiler P : Low-dose cholestipol plus fenofibrate : Effects on plasma lipoproteins, lecithin : cholesterol acyltransferase, and postheparin lipases in familial hypercholesterolemia. Metabolism, 38 : 271-274, 1989",
      "DOI": "10.1016/0026-0495(89)90086-3"
    },
    {
      "key": "66",
      "doi-asserted-by": "crossref",
      "unstructured": "(66) Deeb S and Peng R : Structure of the human lipoprotein lipase gene. Biochemistry, 28 : 4131-4135, 1989",
      "DOI": "10.1021/bi00436a001"
    },
    {
      "key": "67",
      "doi-asserted-by": "crossref",
      "unstructured": "(67) Hua X, Enerback S, Hudson J, Youkhana K, and Gimble JM : Cloning and characterization of the murine lipoprotein lipase-encoding gene : Structural and functional analysis. Gene, 107 : 247-258, 1991",
      "DOI": "10.1016/0378-1119(91)90325-6"
    },
    {
      "key": "68",
      "doi-asserted-by": "crossref",
      "unstructured": "(68) Simpson HS, Williamson CM, Olivecrona T, Pringle S, Maclean J, Lorimer AR, Bonnefous F, Bogaievsky Y, Packard CJ, and Shepherd J : Postprandial lipemia, fenofibrate and coronary artery disease. Atherosclerosis, 85 : 193-202, 1990",
      "DOI": "10.1016/0021-9150(90)90111-U"
    },
    {
      "key": "69",
      "unstructured": "(69) Rouffy J, Goy-Loeper J, Chanu B, Bakir R, and Djian F : Comparative study of reduction in serum lipids obtained with bezafibrate and fenofibrate in twenty patients withtype II hyperlipoproteinemia and low serum HDL. Semaine des HOpitaux, 61 : 2115-2120, 1985"
    },
    {
      "key": "70",
      "doi-asserted-by": "crossref",
      "unstructured": "(70) Aalto-Setalak, Fisher EA, Chen X, Chajek-Shaul T, Hayek T, Zechner R, Walsh A, Ramakrishnan R, Ginsberg HN, and Breslow JL : Mechanism of hypertrig-lyceridemia in human apolipoprotein (apo) CIII transgenic mice. Diminished very low density lipoprotein fractional catabolic rate associated with increased apo C-III and reduced apo E on the particles. J Clin Invest, 90 : 1889-1900, 1992",
      "DOI": "10.1172/JCI116066"
    },
    {
      "key": "71",
      "doi-asserted-by": "crossref",
      "unstructured": "(71) Bard JM, Parra HJ, Camare R, Luc G, Ziegler 0, Dachet C, Bruckert E, Douste-Blazy P, Drouin P, Jacotot B, De Gennes JL, Keller U, and Fruchart JC : A multicenter comparison of the effects of simvastatin and fenofibrate therapy in severe primary hypercholesterolemia, with particular emphasis on lipoproteins defined by their apolipoprotein composition. Metabolism, 41 : 498-503, 1992",
      "DOI": "10.1016/0026-0495(92)90208-R"
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