DOI: 10.4049/jimmunol.85.1.99. Blood Clearance of P32-Labeled Vesicular Stomatitis and Newcastle Disease Viruses by the Reticuloendothelial System in Mice

Blood Clearance of P32-Labeled Vesicular Stomatitis and Newcastle Disease Viruses by the Reticuloendothelial System in Mice

10.4049/jimmunol.85.1.99

Crossref journal-article

Oxford University Press (OUP)

The Journal of Immunology (286)

Abstract

Summary Vesicular stomatitis virus (VSV) and Newcastle disease virus (NDV) were grown with P32-containing media. P32-labeled VSV was purified by ammonium sulfate precipitation and differential centrifugation, and NDV by the adsorption-elution technique with erythrocytes. Both virus preparations were shown to be cleared from the blood by the reticuloendothelial cells of the liver when injected intravenously. In the case of NDV, it was observed that previous blockade with Thorotrast slowed the rate of clearance of the virus, whereas treatment with specific antiserum increased the rate of clearance significantly.

Bibliography

Brunner, K. T., Hurez, D., McCluskey, R. T., & Benacerraf, B. (1960). Blood Clearance of P32-Labeled Vesicular Stomatitis and Newcastle Disease Viruses by the Reticuloendothelial System in Mice. The Journal of Immunology, 85(1), 99â105.

Authors 4

K T Brunner (first)
D Hurez (additional)
R T McCluskey (additional)
B Benacerraf (additional)

References 0 Referenced 59

None

Dates

Type	When
Created	2 years, 7 months ago (Jan. 1, 2023, 11:25 a.m.)
Deposited	4 months, 2 weeks ago (April 6, 2025, 11:03 p.m.)
Indexed	3 months, 2 weeks ago (May 10, 2025, 3:28 a.m.)
Issued	65 years, 1 month ago (July 1, 1960)
Published	65 years, 1 month ago (July 1, 1960)
Published Online	65 years, 1 month ago (July 1, 1960)
Published Print	65 years, 1 month ago (July 1, 1960)

Funders 0

None

BibTeX

@article{Brunner_1960, title={Blood Clearance of P32-Labeled Vesicular Stomatitis and Newcastle Disease Viruses by the Reticuloendothelial System in Mice}, volume={85}, ISSN={0022-1767}, url={http://dx.doi.org/10.4049/jimmunol.85.1.99}, DOI={10.4049/jimmunol.85.1.99}, number={1}, journal={The Journal of Immunology}, publisher={Oxford University Press (OUP)}, author={Brunner, K T and Hurez, D and McCluskey, R T and Benacerraf, B}, year={1960}, month=jul, pages={99–105} }

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