DOI: 10.4049/jimmunol.73.1.49. Inhibition of Antibody Formation in Mature Rabbits by Contact with the Antigen at an Early Age

Inhibition of Antibody Formation in Mature Rabbits by Contact with the Antigen at an Early Age

10.4049/jimmunol.73.1.49

Crossref journal-article

Oxford University Press (OUP)

The Journal of Immunology (286)

Abstract

Summary Rabbits subjected to early immunization with bovine serum albumin failed to develop antibody to bovine serum albumin either during the initial immunization or when mature. Evidence was also obtained that formation of antibody to an unrelated antigen (egg albumin) may be affected. The gamma globulin content of the sera of these animals was as high as or higher than the gamma globulin content of the sera of control animals in which antibody production was not affected.

Bibliography

Hanan, R., & Oyama, J. (1954). Inhibition of Antibody Formation in Mature Rabbits by Contact with the Antigen at an Early Age. The Journal of Immunology, 73(1), 49â53.

Authors 2

Robert Hanan (first)
Jiro Oyama (additional)

References 0 Referenced 87

None

Dates

Type	When
Created	2 years, 7 months ago (Jan. 1, 2023, 10:22 a.m.)
Deposited	4 months, 2 weeks ago (April 8, 2025, 2:25 a.m.)
Indexed	4 months, 2 weeks ago (April 9, 2025, 12:13 a.m.)
Issued	71 years, 1 month ago (July 1, 1954)
Published	71 years, 1 month ago (July 1, 1954)
Published Online	71 years, 1 month ago (July 1, 1954)
Published Print	71 years, 1 month ago (July 1, 1954)

Funders 0

None

BibTeX

@article{Hanan_1954, title={Inhibition of Antibody Formation in Mature Rabbits by Contact with the Antigen at an Early Age}, volume={73}, ISSN={1550-6606}, url={http://dx.doi.org/10.4049/jimmunol.73.1.49}, DOI={10.4049/jimmunol.73.1.49}, number={1}, journal={The Journal of Immunology}, publisher={Oxford University Press (OUP)}, author={Hanan, Robert and Oyama, Jiro}, year={1954}, month=jul, pages={49–53} }

JSON

{
  "indexed": {
    "date-parts": [
      [
        2025,
        4,
        9
      ]
    ],
    "date-time": "2025-04-09T04:13:02Z",
    "timestamp": 1744171982774,
    "version": "3.40.3"
  },
  "reference-count": 0,
  "publisher": "Oxford University Press (OUP)",
  "issue": "1",
  "license": [
    {
      "start": {
        "date-parts": [
          [
            1954,
            7,
            1
          ]
        ],
        "date-time": "1954-07-01T00:00:00Z",
        "timestamp": -489283200000
      },
      "content-version": "vor",
      "delay-in-days": 0,
      "URL": "https://academic.oup.com/pages/standard-publication-reuse-rights"
    }
  ],
  "content-domain": {
    "domain": [],
    "crossmark-restriction": false
  },
  "published-print": {
    "date-parts": [
      [
        1954,
        7,
        1
      ]
    ]
  },
  "abstract": "<jats:title>Summary</jats:title>\n               <jats:p>Rabbits subjected to early immunization with bovine serum albumin failed to develop antibody to bovine serum albumin either during the initial immunization or when mature. Evidence was also obtained that formation of antibody to an unrelated antigen (egg albumin) may be affected.</jats:p>\n               <jats:p>The gamma globulin content of the sera of these animals was as high as or higher than the gamma globulin content of the sera of control animals in which antibody production was not affected.</jats:p>",
  "DOI": "10.4049/jimmunol.73.1.49",
  "type": "journal-article",
  "created": {
    "date-parts": [
      [
        2023,
        1,
        1
      ]
    ],
    "date-time": "2023-01-01T15:22:52Z",
    "timestamp": 1672586572000
  },
  "page": "49-53",
  "source": "Crossref",
  "is-referenced-by-count": 87,
  "title": "Inhibition of Antibody Formation in Mature Rabbits by Contact with the Antigen at an Early Age",
  "prefix": "10.1093",
  "volume": "73",
  "author": [
    {
      "given": "Robert",
      "family": "Hanan",
      "sequence": "first",
      "affiliation": [
        {
          "name": "U. S. Department of Health, Education, and Welfare, Public Health Service, National Institutes of Health, National Microbiological Institute, Laboratory of Infectious Diseases From the , Bethesda, Md."
        }
      ]
    },
    {
      "given": "Jiro",
      "family": "Oyama",
      "sequence": "additional",
      "affiliation": [
        {
          "name": "U. S. Department of Health, Education, and Welfare, Public Health Service, National Institutes of Health, National Microbiological Institute, Laboratory of Infectious Diseases From the , Bethesda, Md."
        }
      ]
    }
  ],
  "member": "286",
  "published-online": {
    "date-parts": [
      [
        1954,
        7,
        1
      ]
    ]
  },
  "container-title": "The Journal of Immunology",
  "original-title": [],
  "language": "en",
  "link": [
    {
      "URL": "https://academic.oup.com/jimmunol/article-pdf/73/1/49/62818717/ji0730010049.pdf",
      "content-type": "application/pdf",
      "content-version": "vor",
      "intended-application": "syndication"
    },
    {
      "URL": "https://academic.oup.com/jimmunol/article-pdf/73/1/49/62818717/ji0730010049.pdf",
      "content-type": "unspecified",
      "content-version": "vor",
      "intended-application": "similarity-checking"
    }
  ],
  "deposited": {
    "date-parts": [
      [
        2025,
        4,
        8
      ]
    ],
    "date-time": "2025-04-08T06:25:01Z",
    "timestamp": 1744093501000
  },
  "score": 1,
  "resource": {
    "primary": {
      "URL": "https://academic.oup.com/jimmunol/article/73/1/49/8101152"
    }
  },
  "subtitle": [],
  "short-title": [],
  "issued": {
    "date-parts": [
      [
        1954,
        7,
        1
      ]
    ]
  },
  "references-count": 0,
  "journal-issue": {
    "issue": "1",
    "published-print": {
      "date-parts": [
        [
          1954,
          7,
          1
        ]
      ]
    }
  },
  "URL": "http://dx.doi.org/10.4049/jimmunol.73.1.49",
  "relation": {},
  "ISSN": [
    "0022-1767",
    "1550-6606"
  ],
  "subject": [],
  "published-other": {
    "date-parts": [
      [
        1954,
        7
      ]
    ]
  },
  "published": {
    "date-parts": [
      [
        1954,
        7,
        1
      ]
    ]
  }
}