DOI: 10.4049/jimmunol.130.3.1313. The equilibrium constant for the interaction between a monoclonal Fab fragment and an influenza virus neuraminidase.

The equilibrium constant for the interaction between a monoclonal Fab fragment and an influenza virus neuraminidase.

10.4049/jimmunol.130.3.1313

Crossref journal-article

Oxford University Press (OUP)

The Journal of Immunology (286)

Abstract

Abstract The affinity or equilibrium constant between an Fab fragment derived from monoclonal IgG directed against influenza virus neuraminidase was measured as 4.1 X 10(7) M-1. The method, which makes use of an air-driven ultracentrifuge, is simple and uses extremely small amounts (10(-11) mol) of material. Furthermore, interpretation of the data is based on sound theoretical considerations. The technique also allows m.w. of the interacting species to be measured and the stoichiometry of the reaction to be determined.

Bibliography

Jackson, D. C., Howlett, G. J., Nestorowicz, A., & Webster, R. G. (1983). The equilibrium constant for the interaction between a monoclonal Fab fragment and an influenza virus neuraminidase. The Journal of Immunology, 130(3), 1313â1316.

Authors 4

D C Jackson (first)
G J Howlett (additional)
A Nestorowicz (additional)
R G Webster (additional)

References 0 Referenced 15

None

Dates

Type	When
Created	2 years, 7 months ago (Dec. 30, 2022, 8:02 p.m.)
Deposited	4 months, 4 weeks ago (March 31, 2025, 6:57 p.m.)
Indexed	4 months, 3 weeks ago (April 8, 2025, 10:02 p.m.)
Issued	42 years, 5 months ago (March 1, 1983)
Published	42 years, 5 months ago (March 1, 1983)
Published Online	42 years, 5 months ago (March 1, 1983)
Published Print	42 years, 5 months ago (March 1, 1983)

Funders 0

None

BibTeX

@article{Jackson_1983, title={The equilibrium constant for the interaction between a monoclonal Fab fragment and an influenza virus neuraminidase.}, volume={130}, ISSN={1550-6606}, url={http://dx.doi.org/10.4049/jimmunol.130.3.1313}, DOI={10.4049/jimmunol.130.3.1313}, number={3}, journal={The Journal of Immunology}, publisher={Oxford University Press (OUP)}, author={Jackson, D C and Howlett, G J and Nestorowicz, A and Webster, R G}, year={1983}, month=mar, pages={1313–1316} }

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