Abstract
Abstract Lindahl and co-workers (1, 2) have reported that mouse interferon enhances the expression of H-2 antigens on the surface of murine leukemia L 1210 cells (H-2d) and normal mouse thymocytes and splenic lymphocytes from DBA/2 (H-2d) or C57 BL/6 (H-2b) mice (3) and presented evidence that interferon was the responsible factor (1, 3). Furthermore, inoculation of DBA/2 mice with potent partially purified mouse interferon preparations (or viral or nonviral inducers of endogenous interferon) was also accompanied by a marked increase in the expression of H-2 antigens on the surface of thymocytes and splenic lymphocytes (4). The availability of restricted antisera against determinants controlled by subregions of the H-2 complex (Table I) has permitted us to show that interferon enhances the expression of H-2K and H-2D antigens, while affecting only slightly, or not at all the expression of Ia antigens on mouse lymphocytes.
Dates
Type | When |
---|---|
Created | 2 years, 8 months ago (Dec. 31, 2022, 6:39 p.m.) |
Deposited | 5 months ago (March 31, 2025, 4:54 p.m.) |
Indexed | 4 months, 3 weeks ago (April 8, 2025, 10:21 p.m.) |
Issued | 48 years, 7 months ago (Feb. 1, 1977) |
Published | 48 years, 7 months ago (Feb. 1, 1977) |
Published Online | 48 years, 7 months ago (Feb. 1, 1977) |
Published Print | 48 years, 7 months ago (Feb. 1, 1977) |
@article{Vignaux_1977, title={Differential Effects of Interferon on the Expression of H-2K, H-2D, and Ia Antigens on Mouse Lymphocytes}, volume={118}, ISSN={1550-6606}, url={http://dx.doi.org/10.4049/jimmunol.118.2.721}, DOI={10.4049/jimmunol.118.2.721}, number={2}, journal={The Journal of Immunology}, publisher={Oxford University Press (OUP)}, author={Vignaux, Françoise and Gresser, Ion}, year={1977}, month=feb, pages={721–723} }