DOI: 10.4049/jimmunol.117.6.2171. Subpopulations of Human T Cells Identified by Receptors for Immunoglobulins and Mitogen Responsiveness

Subpopulations of Human T Cells Identified by Receptors for Immunoglobulins and Mitogen Responsiveness

10.4049/jimmunol.117.6.2171

Crossref journal-article

Oxford University Press (OUP)

The Journal of Immunology (286)

Abstract

Abstract Human T lymphocytes in peripheral blood have been shown to have receptors for IgG (Tγ) or IgM (Tµ). Cultured Tγ cells do not express receptors for IgM and purified Tµ cells do not have receptors for IgG, thus they appear to be distinct T cell populations. Although the two subpopulations show similar response patterns to concanavalin A, Tµ and Tγ cells exhibit different dose-response curves to phytohemagglutinin. The normal response pattern to phytohemagglutinin requires a mixture of T cell subpopulations suggesting that synergistic interactions may occur.

Bibliography

Moretta, L., Ferrarini, M., Mingari, M. C., Moretta, A., & Webb, S. R. (1976). Subpopulations of Human T Cells Identified by Receptors for Immunoglobulins and Mitogen Responsiveness. The Journal of Immunology, 117(6), 2171â2174.

Authors 5

Lorenzo Moretta (first)
Manlio Ferrarini (additional)
Maria C Mingari (additional)
Alessandro Moretta (additional)
Susan R Webb (additional)

References 0 Referenced 284

None

Dates

Type	When
Created	2 years, 8 months ago (Dec. 30, 2022, 4:41 p.m.)
Deposited	5 months ago (March 31, 2025, 4:53 p.m.)
Indexed	2 months, 4 weeks ago (June 4, 2025, 7:08 a.m.)
Issued	48 years, 9 months ago (Dec. 1, 1976)
Published	48 years, 9 months ago (Dec. 1, 1976)
Published Online	48 years, 9 months ago (Dec. 1, 1976)
Published Print	48 years, 9 months ago (Dec. 1, 1976)

Funders 0

None

BibTeX

@article{Moretta_1976, title={Subpopulations of Human T Cells Identified by Receptors for Immunoglobulins and Mitogen Responsiveness}, volume={117}, ISSN={1550-6606}, url={http://dx.doi.org/10.4049/jimmunol.117.6.2171}, DOI={10.4049/jimmunol.117.6.2171}, number={6}, journal={The Journal of Immunology}, publisher={Oxford University Press (OUP)}, author={Moretta, Lorenzo and Ferrarini, Manlio and Mingari, Maria C and Moretta, Alessandro and Webb, Susan R}, year={1976}, month=dec, pages={2171–2174} }

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