DOI: 10.4049/jimmunol.101.1.43. Latency in Human Infections with Tric Agents

Latency in Human Infections with Tric Agents

10.4049/jimmunol.101.1.43

Crossref journal-article

Oxford University Press (OUP)

The Journal of Immunology (286)

Abstract

Summary Direct immunofluorescent staining of conjunctival cells is, at present, the most sensitive method for the detection of TRIC agents. Detailed evidence for the specificity of the method is provided. By means of immunofluorescent staining, TRIC agents can be detected in specimens from the eye of many individuals who do not exhibit current clinical activity of trachoma or inclusion conjunctivitis. Examples from spontaneously infected individuals and from experimental infection in volunteers support the belief that latent infection with TRIC agents is commonplace and may occupy an important role in the natural history of these infections which involve many millions of people. We propose that the clinical signs of activity in trachoma and inclusion conjunctivitis do not adequately reflect the presence of the infectious agent. Future considerations of diagnosis, treatment and control must include subclinical infection and latency of TRIC agents.

Bibliography

Hanna, L., Dawson, C. R., Briones, O., Thygeson, P., & Jawetz, E. (1968). Latency in Human Infections with Tric Agents. The Journal of Immunology, 101(1), 43â50.

Authors 5

Lavelle Hanna (first)
Chandler R Dawson (additional)
Odeon Briones (additional)
Phillips Thygeson (additional)
Ernest Jawetz (additional)

References 0 Referenced 30

None

Dates

Type	When
Created	2 years, 8 months ago (Dec. 30, 2022, 1:59 p.m.)
Deposited	4 months, 3 weeks ago (April 7, 2025, 1:11 a.m.)
Indexed	4 months, 3 weeks ago (April 7, 2025, 1:40 a.m.)
Issued	57 years, 2 months ago (July 1, 1968)
Published	57 years, 2 months ago (July 1, 1968)
Published Online	57 years, 2 months ago (July 1, 1968)
Published Print	57 years, 2 months ago (July 1, 1968)

Funders 0

None

BibTeX

@article{Hanna_1968, title={Latency in Human Infections with Tric Agents}, volume={101}, ISSN={1550-6606}, url={http://dx.doi.org/10.4049/jimmunol.101.1.43}, DOI={10.4049/jimmunol.101.1.43}, number={1}, journal={The Journal of Immunology}, publisher={Oxford University Press (OUP)}, author={Hanna, Lavelle and Dawson, Chandler R and Briones, Odeon and Thygeson, Phillips and Jawetz, Ernest}, year={1968}, month=jul, pages={43–50} }

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