DOI: 10.3390/ijms16059866. Structural Insights into tRNA Dynamics on the Ribosome

Structural Insights into tRNA Dynamics on the Ribosome

10.3390/ijms16059866

Crossref journal-article

MDPI AG

International Journal of Molecular Sciences (1968)

Abstract

High-resolution structures at different stages, as well as biochemical, single molecule and computational approaches have highlighted the elasticity of tRNA molecules when bound to the ribosome. It is well acknowledged that the inherent structural flexibility of the tRNA lies at the heart of the protein synthesis process. Here, we review the recent advances and describe considerations that the conformational changes of the tRNA molecules offer about the mechanisms grounded in translation.

Bibliography

Agirrezabala, X., & Valle, M. (2015). Structural Insights into tRNA Dynamics on the Ribosome. International Journal of Molecular Sciences, 16(5), 9866â9895.

Authors 2

Xabier Agirrezabala (first)
Mikel Valle (additional)

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Dates

Type	When
Created	10 years, 4 months ago (April 30, 2015, 3:51 a.m.)
Deposited	1 year, 3 months ago (June 3, 2024, 4:12 a.m.)
Indexed	5 months, 2 weeks ago (March 19, 2025, 6:46 a.m.)
Issued	10 years, 4 months ago (April 30, 2015)
Published	10 years, 4 months ago (April 30, 2015)
Published Online	10 years, 4 months ago (April 30, 2015)

Funders 1

Spanish Ministry of Economy and Competitiveness
Awards1
1. BFU2012-34873

BibTeX

@article{Agirrezabala_2015, title={Structural Insights into tRNA Dynamics on the Ribosome}, volume={16}, ISSN={1422-0067}, url={http://dx.doi.org/10.3390/ijms16059866}, DOI={10.3390/ijms16059866}, number={5}, journal={International Journal of Molecular Sciences}, publisher={MDPI AG}, author={Agirrezabala, Xabier and Valle, Mikel}, year={2015}, month=apr, pages={9866–9895} }

JSON

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  "abstract": "<jats:p>High-resolution structures at different stages, as well as biochemical, single molecule and computational approaches have highlighted the elasticity of tRNA molecules when bound to the ribosome. It is well acknowledged that the inherent structural flexibility of the tRNA lies at the heart of the protein synthesis process. Here, we review the recent advances and describe considerations that the conformational changes of the tRNA molecules offer about the mechanisms grounded in translation.</jats:p>",
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  "page": "9866-9895",
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  "title": "Structural Insights into tRNA Dynamics on the Ribosome",
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      "given": "Xabier",
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      "given": "Mikel",
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          "name": "Structural Biology Unit, CICbioGUNE Biscay Technology Park, Bld 800,  48610 Derio, Basque Country, Spain"
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