DOI: 10.3171/jns.1977.46.3.0290. Ruptured intracranial aneurysms

10.3171/jns.1977.46.3.0290

Crossref journal-article

Journal of Neurosurgery Publishing Group (JNSPG)

Journal of Neurosurgery (1754)

Abstract

✓ The authors review 100 consecutive cases of ruptured intracranial aneurysms to assess the overall morbidity and mortality. Patients were placed on a regimen of bed rest, sedation, control of blood pressure, anticonvulsants, and antifibrinolytic therapy. Surgery was performed on 86 patients with hypotensive anesthesia and microsurgical techniques. The incidence of early rebleeding while on epsilon aminocaproic acid and control of blood pressure was 11.8%. The overall surgical mortality was 8.1%, and the surgical mortality of patients in Grades 1, 2, and 3 was 6.3%. Of the 100 patients, 60 were able to return to their prior activities, and 25 had moderate neurological deficits that required limitation of their activities. The total case mortality was 15%. The evidence presented indicates that the regimen of active medical treatment before microsurgical intervention has improved the overall case morbidity and mortality, as well as the chance for long-term survival.

Bibliography

Post, K. D., Flamm, E. S., Goodgold, A., & Ransohoff, J. (1977). Ruptured intracranial aneurysms. Journal of Neurosurgery, 46(3), 290â295.

Authors 4

Kalmon D. Post (first)
Eugene S. Flamm (additional)
Albert Goodgold (additional)
Joseph Ransohoff (additional)

References 21 Referenced 86

10.1001/archneur.1972.00490160001001 / Arch Neurol / Subarachnoid hemorrhage due to ruptured aneurysms. A simple method of estimating prognosis. by Alvord (1972)
10.3171/jns.1956.13.1.0001 / J Neurosurg / Hypothermia, and interruption of carotid, or carotid and vertebral circulation, in the surgical management of intracranial aneurysms. by Botterell (1956)
{'key': 'b3', 'series-title': 'J Neurosurg', 'first-page': '19', 'article-title': 'Discussion of Hunt WE, Hess RM: Surgical risk as related to time of intervention in the repair of intracranial aneurysms.', 'volume': '28', 'author': 'Drake', 'year': '1968'} / J Neurosurg / Discussion of Hunt WE, Hess RM: Surgical risk as related to time of intervention in the repair of intracranial aneurysms. by Drake (1968)
10.3171/jns.1968.29.4.0372 / J Neurosurg / Further experience with surgical treatment of aneurysms of the basilar artery. by Drake (1968)
{'key': 'b5', 'series-title': 'Surg Neurol', 'first-page': '223', 'article-title': 'Treatment of cerebral vasospasm by control of cyclic adenosine monophosphate.', 'volume': '6', 'author': 'Flamm', 'year': '1976'} / Surg Neurol / Treatment of cerebral vasospasm by control of cyclic adenosine monophosphate. by Flamm (1976)
10.3171/jns.1971.35.4.0438 / J Neurosurg / Prognosis for patients with nonsurgically treated aneurysms. Analysis of the Cooperative Study of Intracranial Aneurysms and Subarachnoid Hemorrhage. by Graf (1971)
10.1093/neurosurgery/21.CN_suppl_1.79 / Clin Neurosurg / Timing and preoperative care in intracranial aneurysm surgery. by Hunt (1974)
10.1097/00004424-197505000-00008 / Invest Radiol / Experimental cerebral vasospasm and cyclic adenosine monophosphate (c-AMP). by Kim (1975)
10.3171/jns.1972.37.6.0678 / J Neurosurg / Microsurgical treatment of intracranial saccular aneurysms. by Krayenbühl (1972)
{'key': 'b10', 'series-title': 'Lancet', 'first-page': '417', 'article-title': 'Middle-cerebral aneurysms: further results in the controlled trial of conservative and surgical treatment of ruptured intracranial aneurysms.', 'volume': '2', 'author': 'McKissock', 'year': '1962'} / Lancet / Middle-cerebral aneurysms: further results in the controlled trial of conservative and surgical treatment of ruptured intracranial aneurysms. by McKissock (1962)
10.3171/jns.1968.28.1.0021 / J Neurosurg / Antifibrinolytic therapy for intracrnaial aneurysms. by Mullan (1968)
10.3171/jns.1966.25.5.0574 / J Neurosurg / Report on the Cooperative Study of Intracranial Aneurysms and Subarachnoid Hemorrhage. Section VII, Part 1. Evaluation of the conservative management of ruptured intracranial aneurysms. by Nishioka (1966)
10.3171/jns.1972.36.5.0525 / J Neurosurg / Preoperative management of patients with ruptured intracranial aneurysms. by Ransohoff (1972)
10.3171/jns.1966.25.5.0593 / J Neurosurg / Report on the Cooperative Study of Intracranial Aneurysms and Subarachnoid Hemorrhage. Section VII, Part 2. Hypotension and hypothermia in the treatment of intracranial aneurysms. by Sahs (1966)
{'key': 'b15', 'series-title': 'Intracranial Aneurysms and Subarachnoid Hemorrhage: A Cooperative Study', 'year': '1969'} / Intracranial Aneurysms and Subarachnoid Hemorrhage: A Cooperative Study (1969)
{'key': 'b16', 'series-title': 'NY State J Med', 'first-page': '679', 'article-title': 'Treatment and prevention of stroke. 1. Subarachnoid hemorrhage due to ruptured intracranial aneurysm.', 'volume': '73', 'author': 'Slosberg', 'year': '1973'} / NY State J Med / Treatment and prevention of stroke. 1. Subarachnoid hemorrhage due to ruptured intracranial aneurysm. by Slosberg (1973)
{'key': 'b17', 'series-title': 'Mt Sinai J Med', 'first-page': '82', 'article-title': 'Treatment of ruptured intracranial aneurysms by induced hypotension.', 'volume': '40', 'author': 'Slosberg', 'year': '1973'} / Mt Sinai J Med / Treatment of ruptured intracranial aneurysms by induced hypotension. by Slosberg (1973)
{'key': 'b18', 'series-title': 'Studies on fibrinolysis in the central nervous system with specific reference to intracranial hemorrhages and to the effect on antifibrinolytic drugs. Umea University Medical Dissertations, no. 8', 'author': 'Tovi', 'year': '1972'} / Studies on fibrinolysis in the central nervous system with specific reference to intracranial hemorrhages and to the effect on antifibrinolytic drugs. Umea University Medical Dissertations, no. 8 by Tovi (1972)
10.1111/j.1600-0404.1972.tb07561.x / Acta Neurol Scand / Fibrinolysis and subarachnoid hemorrhage. Inhibitory effect of tranexamic acid. A clinical study. by Tovi (1972)
{'key': 'b20', 'series-title': 'Trans Am Neurol Assoc', 'first-page': '148', 'article-title': 'Late morbidity and mortality in cerebral aneurysms: a ten-year followup of 364 conservatively treated patients with a single cerebral aneurysm.', 'volume': '98', 'author': 'Winn', 'year': '1973'} / Trans Am Neurol Assoc / Late morbidity and mortality in cerebral aneurysms: a ten-year followup of 364 conservatively treated patients with a single cerebral aneurysm. by Winn (1973)
{'key': 'b21', 'series-title': 'Surg Neurol', 'first-page': '7', 'article-title': 'The microsurgical approach to intracranial aneurysms.', 'volume': '3', 'author': 'Yaşargil', 'year': '1975'} / Surg Neurol / The microsurgical approach to intracranial aneurysms. by Yaşargil (1975)

Dates

Type	When
Created	16 years, 3 months ago (May 7, 2009, 11:20 a.m.)
Deposited	3 years, 1 month ago (July 25, 2022, 1:56 a.m.)
Indexed	1 year, 3 months ago (May 23, 2024, 5:09 a.m.)
Issued	48 years, 6 months ago (March 1, 1977)
Published	48 years, 6 months ago (March 1, 1977)
Published Print	48 years, 6 months ago (March 1, 1977)

Funders 0

None

BibTeX

@article{Post_1977, title={Ruptured intracranial aneurysms: Case morbidity and mortality}, volume={46}, ISSN={0022-3085}, url={http://dx.doi.org/10.3171/jns.1977.46.3.0290}, DOI={10.3171/jns.1977.46.3.0290}, number={3}, journal={Journal of Neurosurgery}, publisher={Journal of Neurosurgery Publishing Group (JNSPG)}, author={Post, Kalmon D. and Flamm, Eugene S. and Goodgold, Albert and Ransohoff, Joseph}, year={1977}, month=mar, pages={290–295} }

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