DOI: 10.3171/jns.1974.41.3.0300. Comparative effectiveness of alpha-blockade and beta-stimulation in modifying experimental basilar arterial spasm

Comparative effectiveness of alpha-blockade and beta-stimulation in modifying experimental basilar arterial spasm

10.3171/jns.1974.41.3.0300

Crossref journal-article

Journal of Neurosurgery Publishing Group (JNSPG)

Journal of Neurosurgery (1754)

Abstract

✓The comparative effectiveness of isoproterenol (Isuprel), phentolamine (Regitine), and phenoxybenzamine (Dibenzyline) in modifying basilar arterial spasm induced by the topical application of arterial blood was studied in cats. None of these agents was effective in inhibiting initial peak constriction. Each reduced the duration of the vasospasm. The results indicate that both alpha-blockade and beta-stimulation can alter the course of blood-induced cerebral vasospasm.

Bibliography

Smigiel, M. R., & Sundt, T. M. (1974). Comparative effectiveness of alpha-blockade and beta-stimulation in modifying experimental basilar arterial spasm. Journal of Neurosurgery, 41(3), 300â305.

Authors 2

Mitchell R. Smigiel (first)
Thoralf M. Sundt (additional)

References 23 Referenced 13

10.1016/0026-2862(69)90010-7 / Microvasc Res / Action of acid on the plasticity of venous smooth muscle. by Alexander (1969)
10.3171/jns.1965.22.1.0021 / J Neurosurg / Ruptured intracranial aneurysms — the role of arterial spasm. by Allcock (1965)
10.1016/0026-2862(69)90012-0 / Microvasc Res / Possible role of sodium-calcium pumps in tension development of vascular smooth muscle. by Bohr (1969)
{'key': 'b4', 'series-title': 'The Pulmonary Circulation and Interstitial Space.', 'first-page': '133', 'article-title': 'Activation of vascular smooth muscle', 'author': 'Bohr', 'year': '1969'} / The Pulmonary Circulation and Interstitial Space. / Activation of vascular smooth muscle by Bohr (1969)
10.1136/bmj.1.5745.382 / Br Med J / Intracarotid phenoxybenzamine for cerebral arterial spasm. by Cummins (1971)
{'key': 'b6', 'author': 'Drake'} by Drake
10.3171/jns.1965.23.1.0001 / J Neurosurg / Spasm of basilar and vertebral arteries caused by experimental subarachnoid hemorrhage. by Echlin (1965)
10.3171/jns.1972.37.3.0294 / J Neurosurg / Alteration of experimental cerebral vasospasm by adrenergic blockade. by Flamm (1972)
10.1161/01.STR.1.5.356 / Stroke / Noradrenergic mediation of experimental cerebrovascular spasm. by Fraser (1970)
{'key': 'b10', 'series-title': 'Pharmacol Rev', 'first-page': '183', 'article-title': 'The pharmacology of vascular smooth muscle.', 'volume': '7', 'author': 'Furchgott', 'year': '1955'} / Pharmacol Rev / The pharmacology of vascular smooth muscle. by Furchgott (1955)
{'key': 'b11', 'series-title': 'Angiologica', 'first-page': '129', 'article-title': 'Electromechanical and mechanoelectrical coupling in vascular smooth muscle.', 'volume': '8', 'author': 'Johansson', 'year': '1971'} / Angiologica / Electromechanical and mechanoelectrical coupling in vascular smooth muscle. by Johansson (1971)
10.1161/01.RES.21.5.619 / Circ Res / Electrical and mechanical characteristics of vascular smooth muscle response to norepinephrine and isoproterenol. by Johansson (1967)
{'key': 'b13', 'series-title': 'J Pharmacol Exp Ther', 'first-page': '1', 'article-title': 'Disposition of phenylephrine in vascular tissue, determined by the oil-immersion technique.', 'volume': '163', 'author': 'Kalsner', 'year': '1968'} / J Pharmacol Exp Ther / Disposition of phenylephrine in vascular tissue, determined by the oil-immersion technique. by Kalsner (1968)
10.3171/jns.1968.29.4.0331 / J Neurosurg / Cerebral arterial spasm. by Kapp (1968)
10.1161/01.STR.3.1.49 / Stroke / A model for experimental cerebral arterial spasm. by Kuwayama (1972)
{'key': 'b16', 'series-title': 'The effect of cyclic AMP on cerebral vasospasm.', 'author': 'Peterson'} / The effect of cyclic AMP on cerebral vasospasm. by Peterson
{'key': 'b17', 'series-title': 'Pharmacol Rev', 'first-page': '197', 'article-title': 'Vascular smooth muscle. I. Normal structure, pathology, biochemistry, and biophysics.', 'volume': '20', 'author': 'Somlyo', 'year': '1968'} / Pharmacol Rev / Vascular smooth muscle. I. Normal structure, pathology, biochemistry, and biophysics. by Somlyo (1968)
{'key': 'b18', 'series-title': 'Pharmacol Rev', 'first-page': '249', 'article-title': 'Vascular smooth muscle. II. Pharmacology of normal and hypertensive vessels.', 'volume': '22', 'author': 'Somlyo', 'year': '1970'} / Pharmacol Rev / Vascular smooth muscle. II. Pharmacology of normal and hypertensive vessels. by Somlyo (1970)
{'key': 'b19', 'series-title': 'J Pharmacol Exp Ther', 'first-page': '129', 'article-title': 'Electromechanical and pharmacomechanical coupling in vascular smooth muscle.', 'volume': '159', 'author': 'Somlyo', 'year': '1968'} / J Pharmacol Exp Ther / Electromechanical and pharmacomechanical coupling in vascular smooth muscle. by Somlyo (1968)
{'key': 'b20', 'series-title': 'Mayo Clin Proc', 'first-page': '127', 'article-title': 'The cerebral autonomie nervous system: a proposed physiologic function and pathophysiologic response in subarachnoid hemorrhage and in focal cerebral ischemia.', 'volume': '48', 'author': 'Sundt', 'year': '1973'} / Mayo Clin Proc / The cerebral autonomie nervous system: a proposed physiologic function and pathophysiologic response in subarachnoid hemorrhage and in focal cerebral ischemia. by Sundt (1973)
10.3171/jns.1973.38.5.0557 / J Neurosurg / Treatment of cerebral vasospasm from subarachnoid hemorrhage with isoproterenol and lidocaine hydrochloride. by Sundt (1973)
10.1161/01.CIR.37.2.279 / Circulation / Some aspects of the biological role of adenosine 3′,5′-monophosphate (cyclic AMP). by Sutherland (1968)
10.1161/01.RES.21.4.525 / Circ Res / A method for studying isolated resistance vessels from rabbit mesentery and brain and their responses to drugs. by Uchida (1967)

Dates

Type	When
Created	16 years, 3 months ago (May 7, 2009, 10:56 a.m.)
Deposited	3 years, 1 month ago (July 10, 2022, 7:31 p.m.)
Indexed	11 months, 3 weeks ago (Sept. 9, 2024, 4:31 a.m.)
Issued	51 years ago (Sept. 1, 1974)
Published	51 years ago (Sept. 1, 1974)
Published Print	51 years ago (Sept. 1, 1974)

Funders 0

None

BibTeX

@article{Smigiel_1974, title={Comparative effectiveness of alpha-blockade and beta-stimulation in modifying experimental basilar arterial spasm}, volume={41}, ISSN={0022-3085}, url={http://dx.doi.org/10.3171/jns.1974.41.3.0300}, DOI={10.3171/jns.1974.41.3.0300}, number={3}, journal={Journal of Neurosurgery}, publisher={Journal of Neurosurgery Publishing Group (JNSPG)}, author={Smigiel, Mitchell R. and Sundt, Thoralf M.}, year={1974}, month=sep, pages={300–305} }

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