The Role of Vitamin D in Cancer Prevention
10.2105/ajph.2004.045260
Crossref journal-article
American Public Health Association
American Journal of Public Health (844)
Abstract

Vitamin D status differs by latitude and race, with residents of the northeastern United States and individuals with more skin pigmentation being at increased risk of deficiency. A PubMed database search yielded 63 observational studies of vitamin D status in relation to cancer risk, including 30 of colon, 13 of breast, 26 of prostate, and 7 of ovarian cancer, and several that assessed the association of vitamin D receptor genotype with cancer risk.The majority of studies found a protective relationship between sufficient vitamin D status and lower risk of cancer. The evidence suggests that efforts to improve vitamin D status, for example by vitamin D supplementation, could reduce cancer incidence and mortality at low cost, with few or no adverse effects.

Bibliography

Garland, C. F., Garland, F. C., Gorham, E. D., Lipkin, M., Newmark, H., Mohr, S. B., & Holick, M. F. (2006). The Role of Vitamin D in Cancer Prevention. American Journal of Public Health, 96(2), 252–261.

Authors 7
  1. Cedric F. Garland (first)
  2. Frank C. Garland (additional)
  3. Edward D. Gorham (additional)
  4. Martin Lipkin (additional)
  5. Harold Newmark (additional)
  6. Sharif B. Mohr (additional)
  7. Michael F. Holick (additional)
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Dates
Type When
Created 19 years, 8 months ago (Dec. 27, 2005, 8:34 p.m.)
Deposited 1 year, 6 months ago (Feb. 1, 2024, 6:16 p.m.)
Indexed 18 hours, 55 minutes ago (Aug. 28, 2025, 8:17 a.m.)
Issued 19 years, 6 months ago (Feb. 1, 2006)
Published 19 years, 6 months ago (Feb. 1, 2006)
Published Print 19 years, 6 months ago (Feb. 1, 2006)
Funders 0

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@article{Garland_2006, title={The Role of Vitamin D in Cancer Prevention}, volume={96}, ISSN={1541-0048}, url={http://dx.doi.org/10.2105/ajph.2004.045260}, DOI={10.2105/ajph.2004.045260}, number={2}, journal={American Journal of Public Health}, publisher={American Public Health Association}, author={Garland, Cedric F. and Garland, Frank C. and Gorham, Edward D. and Lipkin, Martin and Newmark, Harold and Mohr, Sharif B. and Holick, Michael F.}, year={2006}, month=feb, pages={252–261} }