DOI: 10.18388/abp.2002_3797. Indocyanine green as a prospective sensitizer for photodynamic therapy of melanomas.

Indocyanine green as a prospective sensitizer for photodynamic therapy of melanomas.

10.18388/abp.2002_3797

Crossref journal-article

Frontiers Media SA

Acta Biochimica Polonica (1965)

Abstract

Spectroscopic, photochemical and biological properties of indocyanine green (ICG) are presented. Light over 800 nm is effectively absorbed by ICG. This property as well as photochemical behaviour of ICG make it a very suitable dye for photodynamic treatment of melanoma cells. Cytotoxicity of ICG itself and the effect of photodynamic therapy (PDT) were evaluated by following the growth of human (SKMEL 188) and mouse (S91) melanoma cells. The surviving fraction of the cells irradiated (lambda(ex) = 830 nm) vs non-irradiated, treated with the same dose of ICG, is significantly decreased (5- to 10-fold). These results show that ICG is a very promising dye for photodynamic therapy of melanomas.

Bibliography

Urbanska, K., Romanowska-Dixon, B., Matuszak, Z., Oszajca, J., Nowak-Sliwinska, P., & Stochel, G. (2002). Indocyanine green as a prospective sensitizer for photodynamic therapy of melanomas. Acta Biochimica Polonica, 49(2), 387â391.

Authors 6

Krystyna Urbanska (first)
Bozena Romanowska-Dixon (additional)
Zenon Matuszak (additional)
Janusz Oszajca (additional)
Patrycja Nowak-Sliwinska (additional)
Grazyna Stochel (additional)

References 0 Referenced 126

None

Dates

Type	When
Created	5 years, 8 months ago (Dec. 12, 2019, 3:50 p.m.)
Deposited	1 year, 3 months ago (May 29, 2024, 9:46 a.m.)
Indexed	4 days, 5 hours ago (Aug. 29, 2025, 6:47 a.m.)
Issued	23 years, 2 months ago (June 30, 2002)
Published	23 years, 2 months ago (June 30, 2002)
Published Online	23 years, 2 months ago (June 30, 2002)

Funders 0

None

BibTeX

@article{Urbanska_2002, title={Indocyanine green as a prospective sensitizer for photodynamic therapy of melanomas.}, volume={49}, ISSN={0001-527X}, url={http://dx.doi.org/10.18388/abp.2002_3797}, DOI={10.18388/abp.2002_3797}, number={2}, journal={Acta Biochimica Polonica}, publisher={Frontiers Media SA}, author={Urbanska, Krystyna and Romanowska-Dixon, Bozena and Matuszak, Zenon and Oszajca, Janusz and Nowak-Sliwinska, Patrycja and Stochel, Grazyna}, year={2002}, month=jun, pages={387–391} }

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