DOI: 10.1593/neo.07103. Molecular Characterization of TMPRSS2-ERG Gene Fusion in the NCI-H660 Prostate Cancer Cell Line: A New Perspective for an Old Model

Molecular Characterization of TMPRSS2-ERG Gene Fusion in the NCI-H660 Prostate Cancer Cell Line: A New Perspective for an Old Model

10.1593/neo.07103

Crossref journal-article

Elsevier BV

Neoplasia (78)

Bibliography

Mertz, K. D., Setlur, S. R., Dhanasekaran, S. M., Demichelis, F., Perner, S., Tomlins, S., Tchinda, J., Laxman, B., Vessella, R. L., Beroukhimt, R., Lee, C., Chinnaiyan, A. M., & Rubin, M. A. (2007). Molecular Characterization of TMPRSS2-ERG Gene Fusion in the NCI-H660 Prostate Cancer Cell Line: A New Perspective for an Old Model. Neoplasia, 9(3), 200-IN3.

Authors 13

Kirsten D. Mertz (first)
Sunita R. Setlur (additional)
Saravana M. Dhanasekaran (additional)
Francesca Demichelis (additional)
Sven Perner (additional)
Scott Tomlins (additional)
Joëlle Tchinda (additional)
Bharathi Laxman (additional)
Robert L. Vessella (additional)
Rameen Beroukhimt (additional)
Charles Lee (additional)
Arul M. Chinnaiyan (additional)
Mark A. Rubin (additional)

References 21 Referenced 115

10.1126/science.1117679 / Science / Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer by Tomlins (2005)
10.1158/0008-5472.CAN-06-0168 / Cancer Res / TMPRSS2.ETV4 gene fusions define a third molecular subtype of prostate cancer by Tomlins (2006)
10.1158/0008-5472.CAN-06-1482 / Cancer Res / TMPRSS2.ERG fusion-associated deletions provide insight into the heterogeneity of prostate cancer by Perner (2006)
{'key': '10.1593/neo.07103_bib4', 'article-title': 'TMPRSS2.ERG gene fusion associated with lethal prostate cancer', 'volume': '2007 Jan 22', 'author': 'Demichelis', 'year': '2007', 'journal-title': 'Oncogene'} / Oncogene / TMPRSS2.ERG gene fusion associated with lethal prostate cancer by Demichelis (2007)
{'key': '10.1593/neo.07103_bib5', 'first-page': '163', 'article-title': 'VCaP, a cell-based model system of human prostate cancer', 'volume': '15', 'author': 'Korenchuk', 'year': '2001', 'journal-title': 'In Vivo'} / In Vivo / VCaP, a cell-based model system of human prostate cancer by Korenchuk (2001)
10.1016/j.urology.2005.10.055 / Urology / Prognostic factors in lymph node-positive prostate cancer by Hofer (2006)
{'key': '10.1593/neo.07103_bib7', 'first-page': '1038', 'article-title': 'Rapid ("warm") autopsy study for procurement of metastatic prostate cancer', 'volume': '6', 'author': 'Rubin', 'year': '2000', 'journal-title': 'Clin Cancer Res'} / Clin Cancer Res / Rapid ("warm") autopsy study for procurement of metastatic prostate cancer by Rubin (2000)
10.1158/0008-5472.CAN-04-2442 / Cancer Res / Androgen-independent prostate cancer is a heterogeneous group of diseases: lessons from a Rapid Autopsy Program by Shah (2004)
10.1158/0008-5472.CAN-06-1966 / Cancer Res / Expression of variant TMPRSS2/ERG fusion messenger RNAs is associated with aggressive prostate cancer by Wang (2006)
10.1186/gb-2002-3-7-research0034 / Genome Biol / Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes by Vandesompele (2002)
10.1038/ng1416 / Nat Genet / Detection of large-scale variation in the human genome by lafrate (2004)
10.1038/nbt869 / Nat Biotechnol / Large-scale genotyping of complex DNA by Kennedy (2003)
10.1093/bioinformatics/bth069 / Bioinformatics / dChipSNP: significance curve and clustering of SNP-array-based lossof-heterozygosity data by Lin (2004)
10.1073/pnas.98.1.31 / Proc Natl Acad Sci USA / Model-based analysis of oligonucleotide arrays: expression index computation and outlier detection by Li (2001)
{'key': '10.1593/neo.07103_bib15', 'first-page': '2913', 'article-title': 'Establishment and identification of small cell lung cancer cell lines having classic and variant features', 'volume': '45', 'author': 'Carney', 'year': '1985', 'journal-title': 'Cancer Res'} / Cancer Res / Establishment and identification of small cell lung cancer cell lines having classic and variant features by Carney (1985)
10.1093/jnci/81.16.1223 / J Natl Cancer Inst / Retention of chromosome 3 in extrapulmonary small cell cancer shown by molecular and cytogenetic studies by Johnson (1989)
{'key': '10.1593/neo.07103_bib17', 'first-page': '225', 'article-title': 'Molecular genetic characterization of neuroendocrine lung cancer cell lines', 'volume': '15', 'author': 'Lai', 'year': '1995', 'journal-title': 'Anticancer Res'} / Anticancer Res / Molecular genetic characterization of neuroendocrine lung cancer cell lines by Lai (1995)
10.1002/pros.10290 / Prostate / Molecular characterization of human prostate carcinoma cell lines by van Bokhoven (2003)
{'key': '10.1593/neo.07103_bib19', 'first-page': '4180', 'article-title': 'Prostate-localized and androgen-regulated expression of the membrane-bound serine protease TMPRSS2', 'volume': '59', 'author': 'Lin', 'year': '1999', 'journal-title': 'Cancer Res'} / Cancer Res / Prostate-localized and androgen-regulated expression of the membrane-bound serine protease TMPRSS2 by Lin (1999)
10.1158/0008-5472.CAN-06-1871 / Cancer Res / TMPRSS2.ERG fusion by translocation or interstitial deletion is highly relevant in androgen-dependent prostate cancer, but is bypassed in late-stage androgen receptor-negative prostate cancer by Hermans (2006)
{'key': '10.1593/neo.07103_bib21', 'article-title': 'Diversity of TMPRSS2-ERG fusion transcripts in the human prostate', 'author': 'Clark', 'year': '2006', 'journal-title': 'Oncogene'} / Oncogene / Diversity of TMPRSS2-ERG fusion transcripts in the human prostate by Clark (2006)

Dates

Type	When
Created	18 years, 5 months ago (March 24, 2007, 8:11 a.m.)
Deposited	6 years, 7 months ago (Jan. 8, 2019, 6:29 a.m.)
Indexed	1 month, 1 week ago (July 25, 2025, 6:08 a.m.)
Issued	18 years, 6 months ago (March 1, 2007)
Published	18 years, 6 months ago (March 1, 2007)
Published Print	18 years, 6 months ago (March 1, 2007)

Funders 0

None

BibTeX

@article{Mertz_2007, title={Molecular Characterization of TMPRSS2-ERG Gene Fusion in the NCI-H660 Prostate Cancer Cell Line: A New Perspective for an Old Model}, volume={9}, ISSN={1476-5586}, url={http://dx.doi.org/10.1593/neo.07103}, DOI={10.1593/neo.07103}, number={3}, journal={Neoplasia}, publisher={Elsevier BV}, author={Mertz, Kirsten D. and Setlur, Sunita R. and Dhanasekaran, Saravana M. and Demichelis, Francesca and Perner, Sven and Tomlins, Scott and Tchinda, Joëlle and Laxman, Bharathi and Vessella, Robert L. and Beroukhimt, Rameen and Lee, Charles and Chinnaiyan, Arul M. and Rubin, Mark A.}, year={2007}, month=mar, pages={200-IN3} }

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