DOI: 10.1557/jmr.2004.19.2.623. Discrete-element method application to mixing and segregation model in industrial blending system

Discrete-element method application to mixing and segregation model in industrial blending system

10.1557/jmr.2004.19.2.623

Crossref journal-article

Springer Science and Business Media LLC

Journal of Materials Research (297)

Abstract

In the pharmaceutical industries, mixing is a critical process. Pharmaceutical products consist of various components, including active ingredient and excipient. After mixing, we should get a homogeneous mixture to ensure the quality of the final products, such as tablets or capsules. For that reason, segregation is an unwanted phenomena in the mixing process. In this study, discrete-element method (DEM) was applied to investigate the mechanism of segregation in a rotating cylinder; basic equipment for powder mixing. In addition, segregation of particles in a rotating cylinder is a very interesting phenomenon and has captured the curiosity of not only industrial engineers, but also physicists. DEM can simulate segregation in a rotating cylinder three-dimensionally. In particular, radial segregation, which was quickly observed, was quantified by computing the granular temperature of the system. Furthermore, particle migration in axial direction, which may be the source of axial segregation, was also shown by the DEM simulation.

Bibliography

Yamane, K. (2004). Discrete-element method application to mixing and segregation model in industrial blending system. Journal of Materials Research, 19(2), 623â627.

Authors 1

Kenji Yamane (first)

References 13 Referenced 17

10.1103/PhysRevLett.84.266
{'key': 'S0884291400086568_ref011', 'first-page': '47', 'volume': '12', 'author': 'Cundall', 'year': '1976', 'journal-title': 'Geotechnique'} / Geotechnique by Cundall (1976)
10.1063/1.869858
10.1016/0032-5910(92)88030-L
10.1103/PhysRevE.52.4393
10.1103/PhysRevLett.73.644
{'key': 'S0884291400086568_ref005', 'first-page': '255', 'author': 'Savage', 'year': '1993', 'journal-title': 'Disorder and Granular Media,'} / Disorder and Granular Media, by Savage (1993)
10.1016/0009-2509(94)E0086-6
10.1063/1.858665
{'key': 'S0884291400086568_ref001', 'first-page': '600', 'volume': '18', 'author': 'Oyama', 'year': '1939', 'journal-title': 'Bull. Inst. Phys. Chem. Rep. (Tokyo)'} / Bull. Inst. Phys. Chem. Rep. (Tokyo) by Oyama (1939)
{'key': 'S0884291400086568_ref006', 'first-page': 'T114', 'volume': '47', 'author': 'Bridgwater', 'year': '1989', 'journal-title': 'Trans. Inst. Chem. Eng.'} / Trans. Inst. Chem. Eng. by Bridgwater (1989)
10.1103/PhysRevLett.78.50
{'key': 'S0884291400086568_ref004', 'first-page': '823', 'volume': '7', 'author': 'Donald', 'year': '1962', 'journal-title': 'Br. Chem. Eng.'} / Br. Chem. Eng. by Donald (1962)

Dates

Type	When
Created	19 years, 10 months ago (Oct. 19, 2005, 12:54 p.m.)
Deposited	4 years, 6 months ago (Feb. 24, 2021, 3:18 p.m.)
Indexed	3 months, 1 week ago (May 16, 2025, 1:23 a.m.)
Issued	21 years, 6 months ago (Feb. 1, 2004)
Published	21 years, 6 months ago (Feb. 1, 2004)
Published Online	14 years, 5 months ago (March 3, 2011)
Published Print	21 years, 6 months ago (Feb. 1, 2004)

Funders 0

None

BibTeX

@article{Yamane_2004, title={Discrete-element method application to mixing and segregation model in industrial blending system}, volume={19}, ISSN={2044-5326}, url={http://dx.doi.org/10.1557/jmr.2004.19.2.623}, DOI={10.1557/jmr.2004.19.2.623}, number={2}, journal={Journal of Materials Research}, publisher={Springer Science and Business Media LLC}, author={Yamane, Kenji}, year={2004}, month=feb, pages={623–627} }

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