DOI: 10.1523/jneurosci.07-01-00201.1987. Collapse of growth cone structure on contact with specific neurites in culture

Collapse of growth cone structure on contact with specific neurites in culture

10.1523/jneurosci.07-01-00201.1987

Crossref journal-article

Society for Neuroscience

The Journal of Neuroscience (393)

Abstract

We have studied the morphology of embryonic chick retinal and sympathetic growth cones as they meet retinal and sympathetic neurites grown in culture. Growth cones preserve their normal morphology and ability to locomote when retinal growth cones contact retinal neurites or when sympathetic growth cones contact sympathetic neurites. Growth cones collapse and their motility ceases when retinal growth cones contact sympathetic neurites or when sympathetic growth cones contact retinal neurites. Collapse was never observed before a growth cone touched a neurite. As a growth cone collapses, the neurite it leads retracts. After a brief pause, a new growth cone is organized and extension recommences. These results suggest that contact-mediated inhibition of locomotion could play a role in growth cone guidance.

Bibliography

Kapfhammer, J., & Raper, J. (1987). Collapse of growth cone structure on contact with specific neurites in culture. The Journal of Neuroscience, 7(1), 201â212.

Authors 2

JP Kapfhammer (first)
JA Raper (additional)

References 0 Referenced 220

None

Dates

Type	When
Created	7 years, 5 months ago (March 30, 2018, 3:30 p.m.)
Deposited	2 years, 4 months ago (April 18, 2023, 9:43 a.m.)
Indexed	2 days, 18 hours ago (Sept. 3, 2025, 6:46 a.m.)
Issued	38 years, 8 months ago (Jan. 1, 1987)
Published	38 years, 8 months ago (Jan. 1, 1987)
Published Online	38 years, 8 months ago (Jan. 1, 1987)
Published Print	38 years, 8 months ago (Jan. 1, 1987)

Funders 0

None

BibTeX

@article{Kapfhammer_1987, title={Collapse of growth cone structure on contact with specific neurites in culture}, volume={7}, ISSN={1529-2401}, url={http://dx.doi.org/10.1523/jneurosci.07-01-00201.1987}, DOI={10.1523/jneurosci.07-01-00201.1987}, number={1}, journal={The Journal of Neuroscience}, publisher={Society for Neuroscience}, author={Kapfhammer, JP and Raper, JA}, year={1987}, month=jan, pages={201–212} }

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