Abstract
AbstractThere is increasing evidence that atherosclerosis is a chronic inflammatory disorder resulting from a combination of processes, and that acute exacerbations of this inflammation are associated with the acute coronary syndromes such as myocardial infarction and unstable angina. Measurement of the serum level of acute phase proteins, such as C-reactive protein and serum amyloid A protein, has been used to predict the risk of acute events in patients with atherosclerosis. Prospective studies have shown that higher serum acute phase protein levels, often within the reference range, are associated with increased risk of myocardial infarction (MI), stroke or peripheral vascular disease and predict risk of infarction and death among high-risk patients. These observations have important implications for the assessment of patients and for treatment.
References
88
Referenced
62
{'key': 'p_1', 'first-page': '298', 'volume': '41', 'author': 'von den Velden R', 'year': '1914', 'journal-title': 'Dtsch. Arch J Klin Med'}
/ Dtsch. Arch J Klin Med by von den Velden R (1914){'key': 'p_2', 'first-page': '1', 'volume': '55', 'author': 'Fahraeus R', 'year': '1921', 'journal-title': 'Acta Med Scand'}
/ Acta Med Scand by Fahraeus R (1921)10.1084/jem.52.4.561
10.1093/infdis/53.1.89
/ J Infect Dis by Ash R (1933)10.1084/jem.73.2.173
10.1084/jem.73.2.191
10.1016/0167-5699(94)90138-4
10.1016/0167-5699(94)90137-6
10.1136/jcp.36.2.203
10.1136/ard.50.10.677
10.1136/jcp.38.3.312
10.1136/bmj.289.6454.1249
10.1016/0009-8981(85)90133-0
10.4049/jimmunol.130.2.885
/ J Immunol by Mortensen RF (1983)10.1038/278259a0
10.1038/362801a0
10.1161/01.CIR.91.11.2844
/ Circulation by Libby P (1995){'key': 'p_18', 'first-page': '1241', 'volume': '21', 'author': 'Barath P', 'year': '1989', 'journal-title': 'Am J Cardiol'}
/ Am J Cardiol by Barath P (1989)10.1161/01.CIR.94.11.2787
/ Circulation by Kaartinen M (1996)10.1161/01.CIR.90.2.694
/ Circulation by Vaddi K (1994)10.1016/S0002-8703(96)90383-X
10.1016/S0140-6736(97)09032-6
10.1161/01.CIR.79.3.549
/ Circulation by Mehta J (1989)10.1056/NEJM197406062902302
/ N Engl J Med by Friedman GD (1974)10.1055/s-0038-1660101
/ Thromb Haemost by Lowe GD (1985)10.1161/01.CIR.94.5.874
/ Circulation by Biasucci LM (1996){'key': 'p_27', 'first-page': '322', 'author': 'Toss H', 'year': '1996', 'journal-title': 'Circulation'}
/ Circulation by Toss H (1996)10.1136/hrt.66.6.425
10.1161/01.CIR.88.2.358
/ Circulation by Mazzone A (1993)10.1016/0735-1097(90)92826-N
/ J Am Coll Cardiol by Dinermain JL (1990)10.1016/0735-1097(95)00524-2
10.1161/01.CIR.86.3.790
/ Circulation by Serneri GG (1992)10.1016/S0735-1097(98)00410-0
10.1161/01.CIR.98.22.2370
/ Circulation by Liuzzo G (1998)10.1161/01.CIR.94.10.2373
/ Circulation by Liuzzo G (1996)10.1016/S0002-9149(97)89141-2
10.1161/01.CIR.94.5.872
/ Circulation by Buja LM (1996)10.1001/archinte.1911.00060080033004
/ Arch Intern Med by Frothingham C (1911)10.1001/jama.1921.02630110008002
/ JAMA by Ophuls W (1921)10.1084/jem.148.1.335
10.1136/hrt.50.2.127
10.1056/NEJM198405033101801
/ N Eng J Med by Davies MJ (1984){'key': 'p_44', 'first-page': '514', 'author': 'Buffon A', 'year': '1996', 'journal-title': 'Circulation'}
/ Circulation by Buffon A (1996)10.1161/01.CIR.92.12.3397
/ Circulation by Grayston JT (1995)10.1093/infdis/167.4.841
/ J Infect Dis by Kuo CC (1993)10.1016/0735-1097(96)00055-1
10.1002/jmv.1890420213
{'key': 'p_49', 'first-page': '739', 'volume': '140', 'author': 'Wu TC', 'year': '1992', 'journal-title': 'Am J Pathol'}
/ Am J Pathol by Wu TC (1992)10.1093/qjmed/89.10.727
/ Q J Med by Cook PJ (1996)10.1161/01.CIR.96.11.4095
/ Circulation by Libby P (1997)10.1016/S0140-6736(88)90741-6
10.1016/0021-9150(94)05480-7
10.1016/S0140-6736(87)90888-9
10.1161/01.CIR.94.5.922
/ Circulation by Nieto FJ (1996)10.1172/JCI119136
10.1097/00007890-199609150-00020
10.1136/hrt.71.5.437
10.1136/bmj.311.7007.711
/ BMJ by Patel P (1995)10.1136/hrt.74.5.497
10.1161/01.CIR.97.17.1675
/ Circulation by Pasceri V (1998)10.1136/bmj.312.7038.1061
/ BMJ by Mendall MA (1996)10.1093/cvr/28.9.1301
10.1136/hrt.47.3.239
10.1172/JCI108932
10.1111/j.0954-6820.1986.tb02769.x
/ Acta Med Scand by Marhaug G (1986)10.1136/jcp.41.12.1263
10.1136/jcp.39.6.635
10.1016/0009-8981(89)90063-6
10.1161/01.ATV.9.3.362
/ Arteriosclerosis by Juhan-Vague I (1989)10.1136/hrt.47.3.239
10.1016/0002-9149(90)90079-G
10.1056/NEJM199408183310701
10.1056/NEJM199503093321003
10.1016/S0140-6736(96)07591-5
10.1016/S0735-1097(98)00136-3
{'key': 'p_77', 'first-page': '493', 'author': 'Ferreiros E', 'year': '1998', 'journal-title': 'Circulation'}
/ Circulation by Ferreiros E (1998){'key': 'p_78', 'first-page': '493', 'author': 'Morrow DA', 'year': '1998', 'journal-title': 'Circulation'}
/ Circulation by Morrow DA (1998)10.1016/S0002-9149(98)00458-5
10.1136/bmj.312.7038.1061
/ BMJ by Mendall MA (1996)10.1093/oxfordjournals.aje.a008963
/ Am J Epidemiol by Kuller L (1996)10.1056/NEJM199704033361401
10.1161/01.CIR.97.5.425
/ Circulation by Ridker PM (1998)10.1161/01.CIR.97.20.2007
/ Circulation by Ridker PM (1998){'key': 'p_85', 'first-page': '99', 'author': 'Koenig W', 'year': '1997', 'journal-title': 'Circulation'}
/ Circulation by Koenig W (1997)10.1161/01.ATV.17.6.1121
/ Arterioscler Thromb Vasc Biol by Tracy R (1997)10.1161/01.CIR.98.9.839
/ Circulation by Ridker PM (1998)10.1177/000456329803500607
/ Ann Clin Biochem by Ledue TB (1998)10.1161/01.CIR.98.8.731
/ Circulation by Ridker PM (1998)
Dates
Type | When |
---|---|
Created | 20 years, 10 months ago (Oct. 13, 2004, 7:19 a.m.) |
Deposited | 2 years, 4 months ago (April 29, 2023, 11:03 a.m.) |
Indexed | 3 months ago (May 27, 2025, 12:29 a.m.) |
Issued | 26 years, 4 months ago (May 1, 1999) |
Published | 26 years, 4 months ago (May 1, 1999) |
Published Online | 20 years, 3 months ago (June 1, 2005) |
Published Print | 26 years, 4 months ago (May 1, 1999) |
@article{Whicher_1999, title={Inflammation, the Acute Phase Response and Atherosclerosis}, volume={37}, ISSN={1434-6621}, url={http://dx.doi.org/10.1515/cclm.1999.080}, DOI={10.1515/cclm.1999.080}, number={5}, journal={cclm}, publisher={Walter de Gruyter GmbH}, author={Whicher, John and Biasucci, Luigi and Rifai, Nader}, year={1999}, month=may, pages={495–503} }