DOI: 10.1371/journal.ppat.1000599. A Cyclic GMP Signalling Module That Regulates Gliding Motility in a Malaria Parasite

A Cyclic GMP Signalling Module That Regulates Gliding Motility in a Malaria Parasite

10.1371/journal.ppat.1000599

Crossref journal-article

Public Library of Science (PLoS)

PLoS Pathogens (340)

Bibliography

Moon, R. W., Taylor, C. J., Bex, C., Schepers, R., Goulding, D., Janse, C. J., Waters, A. P., Baker, D. A., & Billker, O. (2009). A Cyclic GMP Signalling Module That Regulates Gliding Motility in a Malaria Parasite. PLoS Pathogens, 5(9), e1000599.

Authors 9

Robert W. Moon (first)
Cathy J. Taylor (additional)
Claudia Bex (additional)
Rebecca Schepers (additional)
David Goulding (additional)
Chris J. Janse (additional)
Andrew P. Waters (additional)
David A. Baker (additional)
Oliver Billker (additional)

References 56 Referenced 175

10.1016/S0092-8674(00)80511-5 / Cell / TRAP is necessary for gliding motility and infectivity of <italic>Plasmodium</italic> sporozoites. by AA Sultan (1997)
10.1016/S0092-8674(00)81071-5 / Cell / <italic>Toxoplasma</italic> invasion of mammalian cells is powered by the actin cytoskeleton of the parasite. by JM Dobrowolski (1996)
10.1242/jcs.50.1.345 / J Cell Sci / The role of the cytoskeleton in the motility of coccidian sporozoites. by DG Russell (1981)
10.1016/S1471-4922(02)02240-7 / Trends Parasitol / Is <italic>Toxoplasma</italic> egress the first step in invasion? by EF Hoff (2002)
10.1038/nprot.2007.120 / Nat Protoc / Imaging malaria sporozoites in the dermis of the mammalian host. by R Amino (2007)
10.1038/nprot.2007.257 / Nat Protoc / <italic>In vivo</italic> imaging of malaria parasites in the murine liver. by S Thiberge (2007)
10.1038/32667 / Nature / Identification of xanthurenic acid as the putative inducer of malaria development in the mosquito. by O Billker (1998)
10.1111/j.1462-5822.2004.00394.x / Cell Microbiol / Real-time, <italic>in vivo</italic> analysis of malaria ookinete locomotion and mosquito midgut invasion. by D Vlachou (2004)
10.1016/j.tcb.2004.08.002 / Trends Cell Biol / The glideosome: a molecular machine powering motility and host-cell invasion by Apicomplexa. by A Keeley (2004)
10.1074/jbc.M509807200 / J Biol Chem / A conserved molecular motor drives cell invasion and gliding motility across malaria life cycle stages and other apicomplexan parasites. by J Baum (2006)
10.1083/jcb.147.5.937 / J Cell Biol / Conservation of a gliding motility and cell invasion machinery in Apicomplexan parasites. by S Kappe (1999)
10.1016/S1097-2765(03)00113-8 / Mol Cell / Aldolase forms a bridge between cell surface adhesins and the actin cytoskeleton in apicomplexan parasites. by TJ Jewett (2003)
10.1093/emboj/21.9.2149 / Embo J / <italic>Toxoplasma gondii</italic> myosin A and its light chain: a fast, single-headed, plus-end-directed motor. by A Herm-Gotz (2002)
10.1242/jcs.00194 / J Cell Sci / Myosin A tail domain interacting protein (MTIP) localizes to the inner membrane complex of <italic>Plasmodium</italic> sporozoites. by LW Bergman (2003)
10.1083/jcb.200311137 / J Cell Biol / Identification of the membrane receptor of a class XIV myosin in <italic>Toxoplasma gondii</italic>. by E Gaskins (2004)
10.1111/j.1365-2958.2005.05014.x / Molecular Microbiology / A calcium-dependent protein kinase regulates <italic>Plasmodium</italic> ookinete access to the midgut epithelial cell. by T Ishino (2006)
10.1242/jcs.00596 / J Cell Sci / Intracellular calcium stores in <italic>Toxoplasma gondii</italic> govern invasion of host cells. by JL Lovett (2003)
10.1128/IAI.68.6.3667-3673.2000 / Infect Immun / Antibodies against thrombospondin-related anonymous protein do not inhibit <italic>Plasmodium</italic> sporozoite infectivity in vivo. by S Gantt (2000)
10.1038/nrm1679 / Nat Rev Mol Cell Biol / Plants, symbiosis and parasites: a calcium signalling connection. by JF Harper (2005)
10.1111/j.1365-2958.2006.05189.x / Molecular Microbiology / <italic>Plasmodium berghei</italic> calcium-dependent protein kinase 3 is required for ookinete gliding motility and mosquito midgut invasion. by I Siden-Kiamos (2006)
10.1046/j.1365-2958.1997.5671913.x / Mol Microbiol / Participation of myosin in gliding motility and host cell invasion by <italic>Toxoplasma gondii</italic>. by JM Dobrowolski (1997)
10.1074/jbc.M011045200 / J Biol Chem / <italic>Toxoplasma gondii</italic> attachment to host cells is regulated by a calmodulin-like domain protein kinase. by H Kieschnick (2001)
10.1074/jbc.M803129200 / J Biol Chem / The motor complex of <italic>Plasmodium falciparum</italic>: phosphorylation by a calcium-dependent protein kinase. by JL Green (2008)
10.1038/nchembio.87 / Nat Chem Biol / Gene expression signatures and small-molecule compounds link a protein kinase to <italic>Plasmodium falciparum</italic> motility. by N Kato (2008)
{'key': 'ref25', 'article-title': 'Gap45 Phosphorylation Controls Assembly of the <italic>Toxoplasma</italic> Myosin Xiv Complex.', 'author': 'SD Gilk', 'year': '2008', 'journal-title': 'Eukaryot Cell'} / Eukaryot Cell / Gap45 Phosphorylation Controls Assembly of the <italic>Toxoplasma</italic> Myosin Xiv Complex. by SD Gilk (2008)
10.1016/j.ijpara.2003.11.019 / International Journal for Parasitology / A role for coccidian cGMP-dependent protein kinase in motility and invasion. by HI Wiersma (2004)
10.1093/jb/mvj205 / J Biochem (Tokyo) / PbGC{beta} Is Essential for <italic>Plasmodium</italic> Ookinete Motility to Invade Midgut Cell and for Successful Completion of Parasite Life Cycle in Mosquitoes. by M Hirai (2006)
10.1074/jbc.M001021200 / J Biol Chem / Guanylyl cyclase activity associated with putative bifunctional integral membrane proteins in <italic>Plasmodium falciparum</italic>. by DJ Carucci (2000)
10.1371/journal.pbio.0060139 / PLoS Biol / Gametogenesis in Malaria Parasites Is Mediated by the cGMP-Dependent Protein Kinase. by L McRobert (2008)
10.1111/j.1365-2958.2008.06267.x / Molecular Microbiology / Disruption of a <italic>Plasmodium falciparum</italic> cyclic nucleotide phosphodiesterase gene causes aberrant gametogenesis. by CJ Taylor (2008)
10.1093/nar/gkn814 / Nucleic Acids Res / PlasmoDB: a functional genomic database for malaria parasites. by C Aurrecoechea (2009)
10.1016/S0021-9258(18)42609-9 / J Biol Chem / Cyclic nucleotide-binding domains in proteins having diverse functions. by JB Shabb (1992)
10.1126/science.1087025 / Science / Discovery of gene function by expression profiling of the malaria parasite life cycle. by KG Le Roch (2003)
10.1016/j.molbiopara.2005.05.007 / Mol Biochem Parasitol / The <italic>Plasmodium falciparum</italic> sexual development transcriptome: a microarray analysis using ontology-based pattern identification. by JA Young (2005)
10.1093/emboj/18.22.6221 / Embo J / CTRP is essential for mosquito infection by malaria ookinetes. by JT Dessens (1999)
10.1074/jbc.M108393200 / J Biol Chem / Purification and molecular characterization of cGMP-dependent protein kinase from Apicomplexan parasites. A novel chemotherapeutic target. by AM Gurnett (2002)
10.1017/S0031182000056481 / Parasitology / <italic>In vitro</italic> formation of ookinetes and functional maturity of <italic>Plasmodium berghei</italic> gametocytes. by CJ Janse (1985)
10.1016/0020-7519(82)90020-0 / International Journal for Parasitology / Three-dimensional study of the intact cytoskeleton of coccidian sporozoites. by DG Russell (1982)
{'key': 'ref39', 'first-page': '85', 'article-title': 'Cell Biology.', 'author': 'RE Sinden', 'year': '1978'} / Cell Biology. by RE Sinden (1978)
10.1016/S0065-308X(08)60033-0 / Adv Parasitol / Regulation of infectivity of <italic>Plasmodium</italic> to the mosquito vector. by RE Sinden (1996)
10.1371/journal.pbio.0030192 / PLoS Biol / Intravital observation of <italic>Plasmodium berghei</italic> sporozoite infection of the liver. by U Frevert (2005)
10.1093/emboj/18.15.4222 / Embo J / Guanylyl cyclases with the topology of mammalian adenylyl cyclases and an N-terminal P-type ATPase-like domain in <italic>Paramecium</italic>, <italic>Tetrahymena</italic> and <italic>Plasmodium</italic>. by JU Linder (1999)
10.1017/S0031182000046266 / Parasitology / The organisation of the ookinete and observations on nuclear division in oocysts of <italic>Plasmodium berghei</italic>. by EU Canning (1973)
10.1016/j.ijpara.2007.03.005 / Int J Parasitol / Minimum requirements for ookinete to oocyst transformation in <italic>Plasmodium</italic>. by V Carter (2007)
10.1016/S0166-6851(01)00289-4 / Molecular and Biochemical Parasitology / Characterization of the subpellicular network, a filamentous membrane skeletal component in the parasite <italic>Toxoplasma gondii</italic>. by T Mann (2001)
10.1074/jbc.M801302200 / J Biol Chem / IMC1b is a putative membrane skeleton protein involved in cell shape, mechanical strength, motility, and infectivity of malaria ookinetes. by AZ Tremp (2008)
10.1073/pnas.0804738105 / Proc Natl Acad Sci U S A / Compartmentation and compartment-specific regulation of PDE5 by protein kinase G allows selective cGMP-mediated regulation of platelet functions. by LS Wilson (2008)
10.1016/j.ijpara.2008.05.016 / Int J Parasitol / Cyclic nucleotide-specific phosphodiesterases of <italic>Plasmodium falciparum</italic>: PfPDEalpha, a non-essential cGMP-specific PDE that is an integral membrane protein. by L Wentzinger (2008)
10.1016/j.molbiopara.2005.10.020 / Molecular and Biochemical Parasitology / Characterization of <italic>Plasmodium falciparum</italic> cGMP-dependent protein kinase (<italic>Pf</italic>PKG): Antiparasitic activity of a PKG inhibitor. by CA Diaz (2006)
10.1042/BJ20050425 / Biochem J / <italic>Pf</italic>PDE1, a novel cGMP-specific phosphodiesterase from the human malaria parasite <italic>Plasmodium falciparum</italic>. by K Yuasa (2005)
10.1124/pr.58.3.5 / Pharmacol Rev / Cyclic Nucleotide Phosphodiesterases: Molecular Regulation to Clinical Use. by AT Bender (2006)
10.1016/j.chom.2008.02.006 / Cell Host Microbe / A malaria parasite formin regulates actin polymerization and localizes to the parasite-erythrocyte moving junction during invasion. by J Baum (2008)
{'key': 'ref53', 'first-page': '25', 'article-title': 'Maintenance of the <italic>Plasmodium berghei</italic> life cycle.', 'volume': '72', 'author': 'RE Sinden', 'year': '2002', 'journal-title': 'Methods Mol Med'} / Methods Mol Med / Maintenance of the <italic>Plasmodium berghei</italic> life cycle. by RE Sinden (2002)
10.1038/nprot.2006.53 / Nat Protocols / High-efficiency transfection and drug selection of genetically transformed blood stages of the rodent malaria parasite <italic>Plasmodium berghei</italic>. by CJ Janse (2006)
10.1016/S0092-8674(04)00449-0 / Cell / Calcium and a calcium-dependent protein kinase regulate gamete formation and mosquito transmission in a malaria parasite. by O Billker (2004)
10.1016/0076-6879(91)95179-N / Methods Enzymol / Assay of guanylyl cyclase catalytic activity. by SE Domino (1991)

Dates

Type	When
Created	15 years, 11 months ago (Sept. 25, 2009, 8:14 a.m.)
Deposited	3 years, 10 months ago (Oct. 11, 2021, 2:45 a.m.)
Indexed	1 month, 1 week ago (July 20, 2025, 12:10 a.m.)
Issued	15 years, 11 months ago (Sept. 25, 2009)
Published	15 years, 11 months ago (Sept. 25, 2009)
Published Online	15 years, 11 months ago (Sept. 25, 2009)

Funders 0

None

BibTeX

@article{Moon_2009, title={A Cyclic GMP Signalling Module That Regulates Gliding Motility in a Malaria Parasite}, volume={5}, ISSN={1553-7374}, url={http://dx.doi.org/10.1371/journal.ppat.1000599}, DOI={10.1371/journal.ppat.1000599}, number={9}, journal={PLoS Pathogens}, publisher={Public Library of Science (PLoS)}, author={Moon, Robert W. and Taylor, Cathy J. and Bex, Claudia and Schepers, Rebecca and Goulding, David and Janse, Chris J. and Waters, Andrew P. and Baker, David A. and Billker, Oliver}, editor={Sibley, L. David}, year={2009}, month=sep, pages={e1000599} }

JSON

{
  "indexed": {
    "date-parts": [
      [
        2025,
        7,
        20
      ]
    ],
    "date-time": "2025-07-20T04:10:42Z",
    "timestamp": 1752984642633
  },
  "reference-count": 56,
  "publisher": "Public Library of Science (PLoS)",
  "issue": "9",
  "license": [
    {
      "start": {
        "date-parts": [
          [
            2009,
            9,
            25
          ]
        ],
        "date-time": "2009-09-25T00:00:00Z",
        "timestamp": 1253836800000
      },
      "content-version": "unspecified",
      "delay-in-days": 0,
      "URL": "http://creativecommons.org/licenses/by/4.0/"
    }
  ],
  "content-domain": {
    "domain": [
      "www.plospathogens.org"
    ],
    "crossmark-restriction": false
  },
  "DOI": "10.1371/journal.ppat.1000599",
  "type": "journal-article",
  "created": {
    "date-parts": [
      [
        2009,
        9,
        25
      ]
    ],
    "date-time": "2009-09-25T12:14:09Z",
    "timestamp": 1253880849000
  },
  "page": "e1000599",
  "update-policy": "http://dx.doi.org/10.1371/journal.ppat.corrections_policy",
  "source": "Crossref",
  "is-referenced-by-count": 175,
  "title": "A Cyclic GMP Signalling Module That Regulates Gliding Motility in a Malaria Parasite",
  "prefix": "10.1371",
  "volume": "5",
  "author": [
    {
      "given": "Robert W.",
      "family": "Moon",
      "sequence": "first",
      "affiliation": []
    },
    {
      "given": "Cathy J.",
      "family": "Taylor",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "Claudia",
      "family": "Bex",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "Rebecca",
      "family": "Schepers",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "David",
      "family": "Goulding",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "Chris J.",
      "family": "Janse",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "Andrew P.",
      "family": "Waters",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "David A.",
      "family": "Baker",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "Oliver",
      "family": "Billker",
      "sequence": "additional",
      "affiliation": []
    }
  ],
  "member": "340",
  "published-online": {
    "date-parts": [
      [
        2009,
        9,
        25
      ]
    ]
  },
  "reference": [
    {
      "key": "ref1",
      "doi-asserted-by": "crossref",
      "first-page": "511",
      "DOI": "10.1016/S0092-8674(00)80511-5",
      "article-title": "TRAP is necessary for gliding motility and infectivity of <italic>Plasmodium</italic> sporozoites.",
      "volume": "90",
      "author": "AA Sultan",
      "year": "1997",
      "journal-title": "Cell"
    },
    {
      "key": "ref2",
      "doi-asserted-by": "crossref",
      "first-page": "933",
      "DOI": "10.1016/S0092-8674(00)81071-5",
      "article-title": "<italic>Toxoplasma</italic> invasion of mammalian cells is powered by the actin cytoskeleton of the parasite.",
      "volume": "84",
      "author": "JM Dobrowolski",
      "year": "1996",
      "journal-title": "Cell"
    },
    {
      "key": "ref3",
      "doi-asserted-by": "crossref",
      "first-page": "345",
      "DOI": "10.1242/jcs.50.1.345",
      "article-title": "The role of the cytoskeleton in the motility of coccidian sporozoites.",
      "volume": "50",
      "author": "DG Russell",
      "year": "1981",
      "journal-title": "J Cell Sci"
    },
    {
      "key": "ref4",
      "doi-asserted-by": "crossref",
      "first-page": "251",
      "DOI": "10.1016/S1471-4922(02)02240-7",
      "article-title": "Is <italic>Toxoplasma</italic> egress the first step in invasion?",
      "volume": "18",
      "author": "EF Hoff",
      "year": "2002",
      "journal-title": "Trends Parasitol"
    },
    {
      "key": "ref5",
      "doi-asserted-by": "crossref",
      "first-page": "1705",
      "DOI": "10.1038/nprot.2007.120",
      "article-title": "Imaging malaria sporozoites in the dermis of the mammalian host.",
      "volume": "2",
      "author": "R Amino",
      "year": "2007",
      "journal-title": "Nat Protoc"
    },
    {
      "key": "ref6",
      "doi-asserted-by": "crossref",
      "first-page": "1811",
      "DOI": "10.1038/nprot.2007.257",
      "article-title": "<italic>In vivo</italic> imaging of malaria parasites in the murine liver.",
      "volume": "2",
      "author": "S Thiberge",
      "year": "2007",
      "journal-title": "Nat Protoc"
    },
    {
      "key": "ref7",
      "doi-asserted-by": "crossref",
      "first-page": "289",
      "DOI": "10.1038/32667",
      "article-title": "Identification of xanthurenic acid as the putative inducer of malaria development in the mosquito.",
      "volume": "392",
      "author": "O Billker",
      "year": "1998",
      "journal-title": "Nature"
    },
    {
      "key": "ref8",
      "doi-asserted-by": "crossref",
      "first-page": "671",
      "DOI": "10.1111/j.1462-5822.2004.00394.x",
      "article-title": "Real-time, <italic>in vivo</italic> analysis of malaria ookinete locomotion and mosquito midgut invasion.",
      "volume": "6",
      "author": "D Vlachou",
      "year": "2004",
      "journal-title": "Cell Microbiol"
    },
    {
      "key": "ref9",
      "doi-asserted-by": "crossref",
      "first-page": "528",
      "DOI": "10.1016/j.tcb.2004.08.002",
      "article-title": "The glideosome: a molecular machine powering motility and host-cell invasion by Apicomplexa.",
      "volume": "14",
      "author": "A Keeley",
      "year": "2004",
      "journal-title": "Trends Cell Biol"
    },
    {
      "key": "ref10",
      "doi-asserted-by": "crossref",
      "first-page": "5197",
      "DOI": "10.1074/jbc.M509807200",
      "article-title": "A conserved molecular motor drives cell invasion and gliding motility across malaria life cycle stages and other apicomplexan parasites.",
      "volume": "281",
      "author": "J Baum",
      "year": "2006",
      "journal-title": "J Biol Chem"
    },
    {
      "key": "ref11",
      "doi-asserted-by": "crossref",
      "first-page": "937",
      "DOI": "10.1083/jcb.147.5.937",
      "article-title": "Conservation of a gliding motility and cell invasion machinery in Apicomplexan parasites.",
      "volume": "147",
      "author": "S Kappe",
      "year": "1999",
      "journal-title": "J Cell Biol"
    },
    {
      "key": "ref12",
      "doi-asserted-by": "crossref",
      "first-page": "885",
      "DOI": "10.1016/S1097-2765(03)00113-8",
      "article-title": "Aldolase forms a bridge between cell surface adhesins and the actin cytoskeleton in apicomplexan parasites.",
      "volume": "11",
      "author": "TJ Jewett",
      "year": "2003",
      "journal-title": "Mol Cell"
    },
    {
      "key": "ref13",
      "doi-asserted-by": "crossref",
      "first-page": "2149",
      "DOI": "10.1093/emboj/21.9.2149",
      "article-title": "<italic>Toxoplasma gondii</italic> myosin A and its light chain: a fast, single-headed, plus-end-directed motor.",
      "volume": "21",
      "author": "A Herm-Gotz",
      "year": "2002",
      "journal-title": "Embo J"
    },
    {
      "key": "ref14",
      "doi-asserted-by": "crossref",
      "first-page": "39",
      "DOI": "10.1242/jcs.00194",
      "article-title": "Myosin A tail domain interacting protein (MTIP) localizes to the inner membrane complex of <italic>Plasmodium</italic> sporozoites.",
      "volume": "116",
      "author": "LW Bergman",
      "year": "2003",
      "journal-title": "J Cell Sci"
    },
    {
      "key": "ref15",
      "doi-asserted-by": "crossref",
      "first-page": "383",
      "DOI": "10.1083/jcb.200311137",
      "article-title": "Identification of the membrane receptor of a class XIV myosin in <italic>Toxoplasma gondii</italic>.",
      "volume": "165",
      "author": "E Gaskins",
      "year": "2004",
      "journal-title": "J Cell Biol"
    },
    {
      "key": "ref16",
      "doi-asserted-by": "crossref",
      "first-page": "1175",
      "DOI": "10.1111/j.1365-2958.2005.05014.x",
      "article-title": "A calcium-dependent protein kinase regulates <italic>Plasmodium</italic> ookinete access to the midgut epithelial cell.",
      "volume": "59",
      "author": "T Ishino",
      "year": "2006",
      "journal-title": "Molecular Microbiology"
    },
    {
      "key": "ref17",
      "doi-asserted-by": "crossref",
      "first-page": "3009",
      "DOI": "10.1242/jcs.00596",
      "article-title": "Intracellular calcium stores in <italic>Toxoplasma gondii</italic> govern invasion of host cells.",
      "volume": "116",
      "author": "JL Lovett",
      "year": "2003",
      "journal-title": "J Cell Sci"
    },
    {
      "key": "ref18",
      "doi-asserted-by": "crossref",
      "first-page": "3667",
      "DOI": "10.1128/IAI.68.6.3667-3673.2000",
      "article-title": "Antibodies against thrombospondin-related anonymous protein do not inhibit <italic>Plasmodium</italic> sporozoite infectivity in vivo.",
      "volume": "68",
      "author": "S Gantt",
      "year": "2000",
      "journal-title": "Infect Immun"
    },
    {
      "key": "ref19",
      "doi-asserted-by": "crossref",
      "first-page": "555",
      "DOI": "10.1038/nrm1679",
      "article-title": "Plants, symbiosis and parasites: a calcium signalling connection.",
      "volume": "6",
      "author": "JF Harper",
      "year": "2005",
      "journal-title": "Nat Rev Mol Cell Biol"
    },
    {
      "key": "ref20",
      "doi-asserted-by": "crossref",
      "first-page": "1355",
      "DOI": "10.1111/j.1365-2958.2006.05189.x",
      "article-title": "<italic>Plasmodium berghei</italic> calcium-dependent protein kinase 3 is required for ookinete gliding motility and mosquito midgut invasion.",
      "volume": "60",
      "author": "I Siden-Kiamos",
      "year": "2006",
      "journal-title": "Molecular Microbiology"
    },
    {
      "key": "ref21",
      "doi-asserted-by": "crossref",
      "first-page": "163",
      "DOI": "10.1046/j.1365-2958.1997.5671913.x",
      "article-title": "Participation of myosin in gliding motility and host cell invasion by <italic>Toxoplasma gondii</italic>.",
      "volume": "26",
      "author": "JM Dobrowolski",
      "year": "1997",
      "journal-title": "Mol Microbiol"
    },
    {
      "key": "ref22",
      "doi-asserted-by": "crossref",
      "first-page": "12369",
      "DOI": "10.1074/jbc.M011045200",
      "article-title": "<italic>Toxoplasma gondii</italic> attachment to host cells is regulated by a calmodulin-like domain protein kinase.",
      "volume": "276",
      "author": "H Kieschnick",
      "year": "2001",
      "journal-title": "J Biol Chem"
    },
    {
      "key": "ref23",
      "doi-asserted-by": "crossref",
      "first-page": "30980",
      "DOI": "10.1074/jbc.M803129200",
      "article-title": "The motor complex of <italic>Plasmodium falciparum</italic>: phosphorylation by a calcium-dependent protein kinase.",
      "volume": "283",
      "author": "JL Green",
      "year": "2008",
      "journal-title": "J Biol Chem"
    },
    {
      "key": "ref24",
      "doi-asserted-by": "crossref",
      "first-page": "347",
      "DOI": "10.1038/nchembio.87",
      "article-title": "Gene expression signatures and small-molecule compounds link a protein kinase to <italic>Plasmodium falciparum</italic> motility.",
      "volume": "4",
      "author": "N Kato",
      "year": "2008",
      "journal-title": "Nat Chem Biol"
    },
    {
      "key": "ref25",
      "article-title": "Gap45 Phosphorylation Controls Assembly of the <italic>Toxoplasma</italic> Myosin Xiv Complex.",
      "author": "SD Gilk",
      "year": "2008",
      "journal-title": "Eukaryot Cell"
    },
    {
      "key": "ref26",
      "doi-asserted-by": "crossref",
      "first-page": "369",
      "DOI": "10.1016/j.ijpara.2003.11.019",
      "article-title": "A role for coccidian cGMP-dependent protein kinase in motility and invasion.",
      "volume": "34",
      "author": "HI Wiersma",
      "year": "2004",
      "journal-title": "International Journal for Parasitology"
    },
    {
      "key": "ref27",
      "doi-asserted-by": "crossref",
      "first-page": "747",
      "DOI": "10.1093/jb/mvj205",
      "article-title": "PbGC{beta} Is Essential for <italic>Plasmodium</italic> Ookinete Motility to Invade Midgut Cell and for Successful Completion of Parasite Life Cycle in Mosquitoes.",
      "volume": "140",
      "author": "M Hirai",
      "year": "2006",
      "journal-title": "J Biochem (Tokyo)"
    },
    {
      "key": "ref28",
      "doi-asserted-by": "crossref",
      "first-page": "22147",
      "DOI": "10.1074/jbc.M001021200",
      "article-title": "Guanylyl cyclase activity associated with putative bifunctional integral membrane proteins in <italic>Plasmodium falciparum</italic>.",
      "volume": "275",
      "author": "DJ Carucci",
      "year": "2000",
      "journal-title": "J Biol Chem"
    },
    {
      "key": "ref29",
      "doi-asserted-by": "crossref",
      "first-page": "e139",
      "DOI": "10.1371/journal.pbio.0060139",
      "article-title": "Gametogenesis in Malaria Parasites Is Mediated by the cGMP-Dependent Protein Kinase.",
      "volume": "6",
      "author": "L McRobert",
      "year": "2008",
      "journal-title": "PLoS Biol"
    },
    {
      "key": "ref30",
      "doi-asserted-by": "crossref",
      "first-page": "110",
      "DOI": "10.1111/j.1365-2958.2008.06267.x",
      "article-title": "Disruption of a <italic>Plasmodium falciparum</italic> cyclic nucleotide phosphodiesterase gene causes aberrant gametogenesis.",
      "volume": "69",
      "author": "CJ Taylor",
      "year": "2008",
      "journal-title": "Molecular Microbiology"
    },
    {
      "key": "ref31",
      "doi-asserted-by": "crossref",
      "first-page": "D539",
      "DOI": "10.1093/nar/gkn814",
      "article-title": "PlasmoDB: a functional genomic database for malaria parasites.",
      "volume": "37",
      "author": "C Aurrecoechea",
      "year": "2009",
      "journal-title": "Nucleic Acids Res"
    },
    {
      "key": "ref32",
      "doi-asserted-by": "crossref",
      "first-page": "5723",
      "DOI": "10.1016/S0021-9258(18)42609-9",
      "article-title": "Cyclic nucleotide-binding domains in proteins having diverse functions.",
      "volume": "267",
      "author": "JB Shabb",
      "year": "1992",
      "journal-title": "J Biol Chem"
    },
    {
      "key": "ref33",
      "doi-asserted-by": "crossref",
      "first-page": "1503",
      "DOI": "10.1126/science.1087025",
      "article-title": "Discovery of gene function by expression profiling of the malaria parasite life cycle.",
      "volume": "301",
      "author": "KG Le Roch",
      "year": "2003",
      "journal-title": "Science"
    },
    {
      "key": "ref34",
      "doi-asserted-by": "crossref",
      "first-page": "67",
      "DOI": "10.1016/j.molbiopara.2005.05.007",
      "article-title": "The <italic>Plasmodium falciparum</italic> sexual development transcriptome: a microarray analysis using ontology-based pattern identification.",
      "volume": "143",
      "author": "JA Young",
      "year": "2005",
      "journal-title": "Mol Biochem Parasitol"
    },
    {
      "key": "ref35",
      "doi-asserted-by": "crossref",
      "first-page": "6221",
      "DOI": "10.1093/emboj/18.22.6221",
      "article-title": "CTRP is essential for mosquito infection by malaria ookinetes.",
      "volume": "18",
      "author": "JT Dessens",
      "year": "1999",
      "journal-title": "Embo J"
    },
    {
      "key": "ref36",
      "doi-asserted-by": "crossref",
      "first-page": "15913",
      "DOI": "10.1074/jbc.M108393200",
      "article-title": "Purification and molecular characterization of cGMP-dependent protein kinase from Apicomplexan parasites. A novel chemotherapeutic target.",
      "volume": "277",
      "author": "AM Gurnett",
      "year": "2002",
      "journal-title": "J Biol Chem"
    },
    {
      "key": "ref37",
      "doi-asserted-by": "crossref",
      "first-page": "19",
      "DOI": "10.1017/S0031182000056481",
      "article-title": "<italic>In vitro</italic> formation of ookinetes and functional maturity of <italic>Plasmodium berghei</italic> gametocytes.",
      "volume": "91",
      "author": "CJ Janse",
      "year": "1985",
      "journal-title": "Parasitology"
    },
    {
      "key": "ref38",
      "doi-asserted-by": "crossref",
      "first-page": "221",
      "DOI": "10.1016/0020-7519(82)90020-0",
      "article-title": "Three-dimensional study of the intact cytoskeleton of coccidian sporozoites.",
      "volume": "12",
      "author": "DG Russell",
      "year": "1982",
      "journal-title": "International Journal for Parasitology"
    },
    {
      "key": "ref39",
      "first-page": "85",
      "article-title": "Cell Biology.",
      "author": "RE Sinden",
      "year": "1978"
    },
    {
      "key": "ref40",
      "doi-asserted-by": "crossref",
      "first-page": "53",
      "DOI": "10.1016/S0065-308X(08)60033-0",
      "article-title": "Regulation of infectivity of <italic>Plasmodium</italic> to the mosquito vector.",
      "volume": "38",
      "author": "RE Sinden",
      "year": "1996",
      "journal-title": "Adv Parasitol"
    },
    {
      "key": "ref41",
      "doi-asserted-by": "crossref",
      "first-page": "e192",
      "DOI": "10.1371/journal.pbio.0030192",
      "article-title": "Intravital observation of <italic>Plasmodium berghei</italic> sporozoite infection of the liver.",
      "volume": "3",
      "author": "U Frevert",
      "year": "2005",
      "journal-title": "PLoS Biol"
    },
    {
      "key": "ref42",
      "doi-asserted-by": "crossref",
      "first-page": "4222",
      "DOI": "10.1093/emboj/18.15.4222",
      "article-title": "Guanylyl cyclases with the topology of mammalian adenylyl cyclases and an N-terminal P-type ATPase-like domain in <italic>Paramecium</italic>, <italic>Tetrahymena</italic> and <italic>Plasmodium</italic>.",
      "volume": "18",
      "author": "JU Linder",
      "year": "1999",
      "journal-title": "Embo J"
    },
    {
      "key": "ref43",
      "doi-asserted-by": "crossref",
      "first-page": "29",
      "DOI": "10.1017/S0031182000046266",
      "article-title": "The organisation of the ookinete and observations on nuclear division in oocysts of <italic>Plasmodium berghei</italic>.",
      "volume": "67",
      "author": "EU Canning",
      "year": "1973",
      "journal-title": "Parasitology"
    },
    {
      "key": "ref44",
      "doi-asserted-by": "crossref",
      "first-page": "1221",
      "DOI": "10.1016/j.ijpara.2007.03.005",
      "article-title": "Minimum requirements for ookinete to oocyst transformation in <italic>Plasmodium</italic>.",
      "volume": "37",
      "author": "V Carter",
      "year": "2007",
      "journal-title": "Int J Parasitol"
    },
    {
      "key": "ref45",
      "doi-asserted-by": "crossref",
      "first-page": "257",
      "DOI": "10.1016/S0166-6851(01)00289-4",
      "article-title": "Characterization of the subpellicular network, a filamentous membrane skeletal component in the parasite <italic>Toxoplasma gondii</italic>.",
      "volume": "115",
      "author": "T Mann",
      "year": "2001",
      "journal-title": "Molecular and Biochemical Parasitology"
    },
    {
      "key": "ref46",
      "doi-asserted-by": "crossref",
      "first-page": "27604",
      "DOI": "10.1074/jbc.M801302200",
      "article-title": "IMC1b is a putative membrane skeleton protein involved in cell shape, mechanical strength, motility, and infectivity of malaria ookinetes.",
      "volume": "283",
      "author": "AZ Tremp",
      "year": "2008",
      "journal-title": "J Biol Chem"
    },
    {
      "key": "ref47",
      "doi-asserted-by": "crossref",
      "first-page": "13650",
      "DOI": "10.1073/pnas.0804738105",
      "article-title": "Compartmentation and compartment-specific regulation of PDE5 by protein kinase G allows selective cGMP-mediated regulation of platelet functions.",
      "volume": "105",
      "author": "LS Wilson",
      "year": "2008",
      "journal-title": "Proc Natl Acad Sci U S A"
    },
    {
      "key": "ref48",
      "doi-asserted-by": "crossref",
      "first-page": "1625",
      "DOI": "10.1016/j.ijpara.2008.05.016",
      "article-title": "Cyclic nucleotide-specific phosphodiesterases of <italic>Plasmodium falciparum</italic>: PfPDEalpha, a non-essential cGMP-specific PDE that is an integral membrane protein.",
      "volume": "38",
      "author": "L Wentzinger",
      "year": "2008",
      "journal-title": "Int J Parasitol"
    },
    {
      "key": "ref49",
      "doi-asserted-by": "crossref",
      "first-page": "78",
      "DOI": "10.1016/j.molbiopara.2005.10.020",
      "article-title": "Characterization of <italic>Plasmodium falciparum</italic> cGMP-dependent protein kinase (<italic>Pf</italic>PKG): Antiparasitic activity of a PKG inhibitor.",
      "volume": "146",
      "author": "CA Diaz",
      "year": "2006",
      "journal-title": "Molecular and Biochemical Parasitology"
    },
    {
      "key": "ref50",
      "doi-asserted-by": "crossref",
      "first-page": "221",
      "DOI": "10.1042/BJ20050425",
      "article-title": "<italic>Pf</italic>PDE1, a novel cGMP-specific phosphodiesterase from the human malaria parasite <italic>Plasmodium falciparum</italic>.",
      "volume": "392",
      "author": "K Yuasa",
      "year": "2005",
      "journal-title": "Biochem J"
    },
    {
      "key": "ref51",
      "doi-asserted-by": "crossref",
      "first-page": "488",
      "DOI": "10.1124/pr.58.3.5",
      "article-title": "Cyclic Nucleotide Phosphodiesterases: Molecular Regulation to Clinical Use.",
      "volume": "58",
      "author": "AT Bender",
      "year": "2006",
      "journal-title": "Pharmacol Rev"
    },
    {
      "key": "ref52",
      "doi-asserted-by": "crossref",
      "first-page": "188",
      "DOI": "10.1016/j.chom.2008.02.006",
      "article-title": "A malaria parasite formin regulates actin polymerization and localizes to the parasite-erythrocyte moving junction during invasion.",
      "volume": "3",
      "author": "J Baum",
      "year": "2008",
      "journal-title": "Cell Host Microbe"
    },
    {
      "key": "ref53",
      "first-page": "25",
      "article-title": "Maintenance of the <italic>Plasmodium berghei</italic> life cycle.",
      "volume": "72",
      "author": "RE Sinden",
      "year": "2002",
      "journal-title": "Methods Mol Med"
    },
    {
      "key": "ref54",
      "doi-asserted-by": "crossref",
      "first-page": "346",
      "DOI": "10.1038/nprot.2006.53",
      "article-title": "High-efficiency transfection and drug selection of genetically transformed blood stages of the rodent malaria parasite <italic>Plasmodium berghei</italic>.",
      "volume": "1",
      "author": "CJ Janse",
      "year": "2006",
      "journal-title": "Nat Protocols"
    },
    {
      "key": "ref55",
      "doi-asserted-by": "crossref",
      "first-page": "503",
      "DOI": "10.1016/S0092-8674(04)00449-0",
      "article-title": "Calcium and a calcium-dependent protein kinase regulate gamete formation and mosquito transmission in a malaria parasite.",
      "volume": "117",
      "author": "O Billker",
      "year": "2004",
      "journal-title": "Cell"
    },
    {
      "key": "ref56",
      "doi-asserted-by": "crossref",
      "first-page": "345",
      "DOI": "10.1016/0076-6879(91)95179-N",
      "article-title": "Assay of guanylyl cyclase catalytic activity.",
      "volume": "195",
      "author": "SE Domino",
      "year": "1991",
      "journal-title": "Methods Enzymol"
    }
  ],
  "container-title": "PLoS Pathogens",
  "original-title": [],
  "language": "en",
  "link": [
    {
      "URL": "http://dx.plos.org/10.1371/journal.ppat.1000599",
      "content-type": "unspecified",
      "content-version": "vor",
      "intended-application": "similarity-checking"
    }
  ],
  "deposited": {
    "date-parts": [
      [
        2021,
        10,
        11
      ]
    ],
    "date-time": "2021-10-11T06:45:36Z",
    "timestamp": 1633934736000
  },
  "score": 1,
  "resource": {
    "primary": {
      "URL": "https://dx.plos.org/10.1371/journal.ppat.1000599"
    }
  },
  "subtitle": [],
  "editor": [
    {
      "given": "L. David",
      "family": "Sibley",
      "sequence": "first",
      "affiliation": []
    }
  ],
  "short-title": [],
  "issued": {
    "date-parts": [
      [
        2009,
        9,
        25
      ]
    ]
  },
  "references-count": 56,
  "journal-issue": {
    "issue": "9",
    "published-online": {
      "date-parts": [
        [
          2009,
          9,
          25
        ]
      ]
    }
  },
  "URL": "http://dx.doi.org/10.1371/journal.ppat.1000599",
  "relation": {},
  "ISSN": [
    "1553-7374"
  ],
  "subject": [],
  "container-title-short": "PLoS Pathog",
  "published": {
    "date-parts": [
      [
        2009,
        9,
        25
      ]
    ]
  }
}