DOI: 10.1371/journal.pbio.0020137. Noise Minimization in Eukaryotic Gene Expression

Noise Minimization in Eukaryotic Gene Expression

10.1371/journal.pbio.0020137

Crossref journal-article

Public Library of Science (PLoS)

PLoS Biology (340)

Bibliography

Fraser, H. B., Hirsh, A. E., Giaever, G., Kumm, J., & Eisen, M. B. (2004). Noise Minimization in Eukaryotic Gene Expression. PLoS Biology, 2(6), e137.

Authors 5

Hunter B Fraser (first)
Aaron E Hirsh (additional)
Guri Giaever (additional)
Jochen Kumm (additional)
Michael B Eisen (additional)

References 23 Referenced 345

10.1073/pnas.0635171100 / Proc Natl Acad Sci U S A / Genome-wide analysis of mRNA translation profiles in Saccharomyces cerevisiae. (2003)
10.1093/genetics/149.4.1633 / Genetics / Stochastic kinetic analysis of developmental pathway bifurcation in phage lambda-infected Escherichia coli cells. (1998)
10.1038/35002258 / Nature / Circadian clocks limited by noise. (2000)
10.1016/0022-5193(78)90326-0 / J Theor Biol / A model for the statistical fluctuations of protein numbers in a microbial population. (1978)
10.1038/nature01546 / Nature / Noise in eukaryotic gene expression. (2003)
10.1126/science.1070919 / Science / Stochastic gene expression in a single cell. (2002)
10.1126/science.1068696 / Science / Evolutionary rate in the protein interaction network. (2002)
10.1038/415141a / Nature / Functional organization of the yeast proteome by systematic analysis of protein complexes. (2002)
10.1073/pnas.0307490100 / Proc Natl Acad Sci U S A / Chemogenomic profiling: Identifying the functional interactions of small molecules in yeast. (2004)
10.1016/S1369-5274(00)00253-8 / Curr Opin Microbiol / Playing Dr. Jekyll and Mr. Hyde: Combined mechanisms of phase variation in bacteria. (2001)
10.1038/35082561 / Nature / Protein dispensability and rate of evolution. (2001)
10.1038/421497a / Nature / Genomic function: Rate of evolution and gene dispensability [discussion]. (2003)
10.1038/415180a / Nature / Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. (2002)
10.1038/35075138 / Nature / Lethality and centrality in protein networks. (2001)
10.1101/gr.87702 / Genome Res / Essential genes are more evolutionarily conserved than are nonessential genes in bacteria. (2002)
10.1038/ng869 / Nat Genet / Regulation of noise in the expression of a single gene. (2002)
10.1093/genetics/158.2.927 / Genetics / Highly expressed genes in yeast evolve slowly. (2001)
10.1038/421496b / Nature / Genomic function: Rate of evolution and gene dispensability. (2003)
10.1038/nature01771 / Nature / Dosage sensitivity and the evolution of gene families in yeast. (2003)
{'key': 'pbio-0020137-Sokal1', 'article-title': 'Biometry.', 'year': '1994'} / Biometry. (1994)
{'key': 'pbio-0020137-Thattai1', 'first-page': '8614', 'article-title': 'Intrinsic noise in gene regulatory networks.', 'volume': '98', 'year': '2000', 'journal-title': 'Proc Natl Acad Sci U S A'} / Proc Natl Acad Sci U S A / Intrinsic noise in gene regulatory networks. (2000)
10.1038/nature750 / Nature / Comparative assessment of large-scale data sets of protein–protein interactions. (2002)
10.1073/pnas.092538799 / Proc Natl Acad Sci U S A / Precision and functional specificity in mRNA decay. (2002)

Dates

Type	When
Created	21 years, 4 months ago (April 26, 2004, 5:07 p.m.)
Deposited	4 years, 2 months ago (June 16, 2021, 5:50 p.m.)
Indexed	1 month, 1 week ago (July 14, 2025, 11:17 p.m.)
Issued	21 years, 4 months ago (April 27, 2004)
Published	21 years, 4 months ago (April 27, 2004)
Published Online	21 years, 4 months ago (April 27, 2004)

Funders 0

None

BibTeX

@article{Fraser_2004, title={Noise Minimization in Eukaryotic Gene Expression}, volume={2}, ISSN={1545-7885}, url={http://dx.doi.org/10.1371/journal.pbio.0020137}, DOI={10.1371/journal.pbio.0020137}, number={6}, journal={PLoS Biology}, publisher={Public Library of Science (PLoS)}, author={Fraser, Hunter B and Hirsh, Aaron E and Giaever, Guri and Kumm, Jochen and Eisen, Michael B}, editor={Ken Wolfe}, year={2004}, month=apr, pages={e137} }

JSON

{
  "indexed": {
    "date-parts": [
      [
        2025,
        7,
        15
      ]
    ],
    "date-time": "2025-07-15T03:17:37Z",
    "timestamp": 1752549457865
  },
  "reference-count": 23,
  "publisher": "Public Library of Science (PLoS)",
  "issue": "6",
  "license": [
    {
      "start": {
        "date-parts": [
          [
            2004,
            4,
            27
          ]
        ],
        "date-time": "2004-04-27T00:00:00Z",
        "timestamp": 1083024000000
      },
      "content-version": "unspecified",
      "delay-in-days": 0,
      "URL": "http://creativecommons.org/licenses/by/4.0/"
    }
  ],
  "content-domain": {
    "domain": [
      "www.plosbiology.org"
    ],
    "crossmark-restriction": false
  },
  "DOI": "10.1371/journal.pbio.0020137",
  "type": "journal-article",
  "created": {
    "date-parts": [
      [
        2004,
        4,
        26
      ]
    ],
    "date-time": "2004-04-26T21:07:30Z",
    "timestamp": 1083013650000
  },
  "page": "e137",
  "update-policy": "http://dx.doi.org/10.1371/journal.pbio.corrections_policy",
  "source": "Crossref",
  "is-referenced-by-count": 345,
  "title": "Noise Minimization in Eukaryotic Gene Expression",
  "prefix": "10.1371",
  "volume": "2",
  "author": [
    {
      "given": "Hunter B",
      "family": "Fraser",
      "sequence": "first",
      "affiliation": []
    },
    {
      "given": "Aaron E",
      "family": "Hirsh",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "Guri",
      "family": "Giaever",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "Jochen",
      "family": "Kumm",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "Michael B",
      "family": "Eisen",
      "sequence": "additional",
      "affiliation": []
    }
  ],
  "member": "340",
  "published-online": {
    "date-parts": [
      [
        2004,
        4,
        27
      ]
    ]
  },
  "reference": [
    {
      "key": "pbio-0020137-Arava1",
      "doi-asserted-by": "crossref",
      "first-page": "3889",
      "DOI": "10.1073/pnas.0635171100",
      "article-title": "Genome-wide analysis of mRNA translation profiles in Saccharomyces cerevisiae.",
      "volume": "100",
      "year": "2003",
      "journal-title": "Proc Natl Acad Sci U S A"
    },
    {
      "key": "pbio-0020137-Arkin1",
      "doi-asserted-by": "crossref",
      "first-page": "1633",
      "DOI": "10.1093/genetics/149.4.1633",
      "article-title": "Stochastic kinetic analysis of developmental pathway bifurcation in phage lambda-infected Escherichia coli cells.",
      "volume": "149",
      "year": "1998",
      "journal-title": "Genetics"
    },
    {
      "key": "pbio-0020137-Barkai1",
      "doi-asserted-by": "crossref",
      "first-page": "267",
      "DOI": "10.1038/35002258",
      "article-title": "Circadian clocks limited by noise.",
      "volume": "403",
      "year": "2000",
      "journal-title": "Nature"
    },
    {
      "key": "pbio-0020137-Berg1",
      "doi-asserted-by": "crossref",
      "first-page": "587",
      "DOI": "10.1016/0022-5193(78)90326-0",
      "article-title": "A model for the statistical fluctuations of protein numbers in a microbial population.",
      "volume": "71",
      "year": "1978",
      "journal-title": "J Theor Biol"
    },
    {
      "key": "pbio-0020137-Blake1",
      "doi-asserted-by": "crossref",
      "first-page": "633",
      "DOI": "10.1038/nature01546",
      "article-title": "Noise in eukaryotic gene expression.",
      "volume": "422",
      "year": "2003",
      "journal-title": "Nature"
    },
    {
      "key": "pbio-0020137-Elowitz1",
      "doi-asserted-by": "crossref",
      "first-page": "1183",
      "DOI": "10.1126/science.1070919",
      "article-title": "Stochastic gene expression in a single cell.",
      "volume": "297",
      "year": "2002",
      "journal-title": "Science"
    },
    {
      "key": "pbio-0020137-Fraser1",
      "doi-asserted-by": "crossref",
      "first-page": "750",
      "DOI": "10.1126/science.1068696",
      "article-title": "Evolutionary rate in the protein interaction network.",
      "volume": "296",
      "year": "2002",
      "journal-title": "Science"
    },
    {
      "key": "pbio-0020137-Gavin1",
      "doi-asserted-by": "crossref",
      "first-page": "141",
      "DOI": "10.1038/415141a",
      "article-title": "Functional organization of the yeast proteome by systematic analysis of protein complexes.",
      "volume": "415",
      "year": "2002",
      "journal-title": "Nature"
    },
    {
      "key": "pbio-0020137-Giaever1",
      "doi-asserted-by": "crossref",
      "first-page": "793",
      "DOI": "10.1073/pnas.0307490100",
      "article-title": "Chemogenomic profiling: Identifying the functional interactions of small molecules in yeast.",
      "volume": "101",
      "year": "2004",
      "journal-title": "Proc Natl Acad Sci U S A"
    },
    {
      "key": "pbio-0020137-Hallet1",
      "doi-asserted-by": "crossref",
      "first-page": "570",
      "DOI": "10.1016/S1369-5274(00)00253-8",
      "article-title": "Playing Dr. Jekyll and Mr. Hyde: Combined mechanisms of phase variation in bacteria.",
      "volume": "4",
      "year": "2001",
      "journal-title": "Curr Opin Microbiol"
    },
    {
      "key": "pbio-0020137-Hirsh1",
      "doi-asserted-by": "crossref",
      "first-page": "1046",
      "DOI": "10.1038/35082561",
      "article-title": "Protein dispensability and rate of evolution.",
      "volume": "411",
      "year": "2001",
      "journal-title": "Nature"
    },
    {
      "key": "pbio-0020137-Hirsh2",
      "doi-asserted-by": "crossref",
      "first-page": "497",
      "DOI": "10.1038/421497a",
      "article-title": "Genomic function: Rate of evolution and gene dispensability [discussion].",
      "volume": "421",
      "year": "2003",
      "journal-title": "Nature"
    },
    {
      "key": "pbio-0020137-Ho1",
      "doi-asserted-by": "crossref",
      "first-page": "180",
      "DOI": "10.1038/415180a",
      "article-title": "Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry.",
      "volume": "415",
      "year": "2002",
      "journal-title": "Nature"
    },
    {
      "key": "pbio-0020137-Jeong1",
      "doi-asserted-by": "crossref",
      "first-page": "41",
      "DOI": "10.1038/35075138",
      "article-title": "Lethality and centrality in protein networks.",
      "volume": "411",
      "year": "2001",
      "journal-title": "Nature"
    },
    {
      "key": "pbio-0020137-Jordan1",
      "doi-asserted-by": "crossref",
      "first-page": "962",
      "DOI": "10.1101/gr.87702",
      "article-title": "Essential genes are more evolutionarily conserved than are nonessential genes in bacteria.",
      "volume": "12",
      "year": "2002",
      "journal-title": "Genome Res"
    },
    {
      "key": "pbio-0020137-Ozbudak1",
      "doi-asserted-by": "crossref",
      "first-page": "69",
      "DOI": "10.1038/ng869",
      "article-title": "Regulation of noise in the expression of a single gene.",
      "volume": "31",
      "year": "2002",
      "journal-title": "Nat Genet"
    },
    {
      "key": "pbio-0020137-Pal1",
      "doi-asserted-by": "crossref",
      "first-page": "927",
      "DOI": "10.1093/genetics/158.2.927",
      "article-title": "Highly expressed genes in yeast evolve slowly.",
      "volume": "158",
      "year": "2001",
      "journal-title": "Genetics"
    },
    {
      "key": "pbio-0020137-Pal2",
      "doi-asserted-by": "crossref",
      "first-page": "496",
      "DOI": "10.1038/421496b",
      "article-title": "Genomic function: Rate of evolution and gene dispensability.",
      "volume": "421",
      "year": "2003",
      "journal-title": "Nature"
    },
    {
      "key": "pbio-0020137-Papp1",
      "doi-asserted-by": "crossref",
      "first-page": "194",
      "DOI": "10.1038/nature01771",
      "article-title": "Dosage sensitivity and the evolution of gene families in yeast.",
      "volume": "424",
      "year": "2003",
      "journal-title": "Nature"
    },
    {
      "key": "pbio-0020137-Sokal1",
      "article-title": "Biometry.",
      "year": "1994"
    },
    {
      "key": "pbio-0020137-Thattai1",
      "first-page": "8614",
      "article-title": "Intrinsic noise in gene regulatory networks.",
      "volume": "98",
      "year": "2000",
      "journal-title": "Proc Natl Acad Sci U S A"
    },
    {
      "key": "pbio-0020137-von1",
      "doi-asserted-by": "crossref",
      "first-page": "399",
      "DOI": "10.1038/nature750",
      "article-title": "Comparative assessment of large-scale data sets of protein\u2013protein interactions.",
      "volume": "417",
      "year": "2002",
      "journal-title": "Nature"
    },
    {
      "key": "pbio-0020137-Wang1",
      "doi-asserted-by": "crossref",
      "first-page": "5860",
      "DOI": "10.1073/pnas.092538799",
      "article-title": "Precision and functional specificity in mRNA decay.",
      "volume": "99",
      "year": "2002",
      "journal-title": "Proc Natl Acad Sci U S A"
    }
  ],
  "container-title": "PLoS Biology",
  "original-title": [],
  "language": "en",
  "link": [
    {
      "URL": "https://dx.plos.org/10.1371/journal.pbio.0020137",
      "content-type": "unspecified",
      "content-version": "vor",
      "intended-application": "similarity-checking"
    }
  ],
  "deposited": {
    "date-parts": [
      [
        2021,
        6,
        16
      ]
    ],
    "date-time": "2021-06-16T21:50:02Z",
    "timestamp": 1623880202000
  },
  "score": 1,
  "resource": {
    "primary": {
      "URL": "https://dx.plos.org/10.1371/journal.pbio.0020137"
    }
  },
  "subtitle": [],
  "editor": [
    {
      "family": "Ken Wolfe",
      "sequence": "first",
      "affiliation": []
    }
  ],
  "short-title": [],
  "issued": {
    "date-parts": [
      [
        2004,
        4,
        27
      ]
    ]
  },
  "references-count": 23,
  "journal-issue": {
    "issue": "6",
    "published-online": {
      "date-parts": [
        [
          2004,
          4,
          27
        ]
      ]
    }
  },
  "URL": "http://dx.doi.org/10.1371/journal.pbio.0020137",
  "relation": {},
  "ISSN": [
    "1545-7885"
  ],
  "subject": [],
  "container-title-short": "PLoS Biol",
  "published": {
    "date-parts": [
      [
        2004,
        4,
        27
      ]
    ]
  }
}