Abstract
Benzo[a]pyrene-7,8-diol-9,10 epoxide (BPDE)-DNA adducts have been analyzed by surface-enhanced Raman scattering (SERS) spectrometry. BPDE is the ultimate carcinogenic metabolite of benzo[a]pyrene. The SERS measurements were performed with the use of a silver-coated cellulose material as the SERS-active substrate. The acid hydrolyzed products of BPDE-DNA adducts, DNA, and the BP-tetrols were also analyzed by SERS. The results indicate that SERS has great promise as a tool for detecting BPDE-DNA adducts in biological samples.
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Dates
Type | When |
---|---|
Created | 20 years, 1 month ago (July 13, 2005, 9:31 p.m.) |
Deposited | 5 months, 3 weeks ago (March 10, 2025, 3:06 p.m.) |
Indexed | 2 months, 2 weeks ago (June 16, 2025, 7:05 p.m.) |
Issued | 38 years, 4 months ago (May 1, 1987) |
Published | 38 years, 4 months ago (May 1, 1987) |
Published Online | 38 years, 4 months ago (May 1, 1987) |
Published Print | 38 years, 4 months ago (May 1, 1987) |
@article{Vo_Dinh_1987, title={Surface-Enhanced Raman Analysis of Benzo[A]Pyrene-DNA Adducts on Silver-Coated Cellulose Substrates}, volume={41}, ISSN={1943-3530}, url={http://dx.doi.org/10.1366/0003702874448616}, DOI={10.1366/0003702874448616}, number={4}, journal={Applied Spectroscopy}, publisher={SAGE Publications}, author={Vo-Dinh, Tuan and Uziel, Mayo and Morrison, Alan L.}, year={1987}, month=may, pages={605–610} }