DOI: 10.1259/bjr.72.863.10700822. Positron emission tomography in breast cancer: a clinicopathological correlation of results.

Positron emission tomography in breast cancer: a clinicopathological correlation of results.

10.1259/bjr.72.863.10700822

Crossref journal-article

Oxford University Press (OUP)

The British Journal of Radiology (286)

Abstract

We conducted a retrospective study to evaluate the sensitivity, specificity and accuracy of positron emission tomography (PET) scans in 109 patients with primary recurrent or metastatic breast cancer. All patients had a PET scan, X-ray or CT scan of the chest, an ultrasound or CT scan of the liver and a bone scan. Mammography was available for 86 patients. Correlation between the PET scan result and histological findings were made. The sensitivity, specificity and accuracy of the PET scan were calculated for both the primary tumour (T) and lymph nodes (N). In patients with metastasis (M) the accuracy of the PET scan was compared with other imaging modalities. Histological results of the site in question were available in only 105 patients. Information for the primary tumour was available for 93 patients and for nodes in 74. The PET scan was accurate in 89.2% for (T), with 3.2% false positive and 7.6% false negative. For (N) the PET scan was accurate in 90.5% with 9.5% false negative. In the 86 patients who underwent both mammography and PET scanning, the PET scan was more accurate in 89.5% versus 72% (p = 0.0003). In the 19 patients with metastasis, the PET scan was in agreement with other imaging modalities in 100% of cases. PET scanning is the only non-invasive imaging procedure that will detect tumours in the breast, lymph nodes, lung, liver, bone and bone marrow with high sensitivity, specificity and accuracy. It is a valuable tool in the management of patients in all stages of breast cancer for diagnosis, staging and following treatment response.

Bibliography

Rostom, A. Y., Powe, J., Kandil, A., Ezzat, A., Bakheet, S., el-Khwsky, F., el-Hussainy, G., Sorbris, R., & Sjoklint, O. (1999). Positron emission tomography in breast cancer: a clinicopathological correlation of results. The British Journal of Radiology, 72(863), 1064â1068.

Authors 9

A Y Rostom (first)
J Powe (additional)
A Kandil (additional)
A Ezzat (additional)
S Bakheet (additional)
F el-Khwsky (additional)
G el-Hussainy (additional)
R Sorbris (additional)
O Sjoklint (additional)

References 10 Referenced 53

10.1016/S0936-6555(05)80033-0
10.1200/JCO.1993.11.11.2101 / J Clin Oncol by Wahl RL (1993)
10.1126/science.123.3191.309
10.1007/BF01249621
10.1002/1097-0142(19931115)72:10<2979::AID-CNCR2820721020>3.0.CO;2-X
{'key': 'p_6', 'first-page': '4', 'volume': '39', 'author': 'Crippa F', 'year': '1998', 'journal-title': 'J Nucl Med'} / J Nucl Med by Crippa F (1998)
10.1016/S0009-9260(87)80394-X
{'key': 'p_8', 'volume-title': 'Breast cancer treatment, cosmetic result.', 'author': 'Fowble B', 'year': '1991'} / Breast cancer treatment, cosmetic result. by Fowble B (1991)
10.1200/JCO.1995.13.6.1470 / J Clin Oncol by Jansson T (1995)
10.1016/S0140-6736(97)24051-1

Dates

Type	When
Created	11 years, 2 months ago (June 12, 2014, 10:08 p.m.)
Deposited	1 year, 7 months ago (Jan. 12, 2024, 11:23 a.m.)
Indexed	1 year, 7 months ago (Jan. 12, 2024, 7:15 p.m.)
Issued	25 years, 10 months ago (Nov. 1, 1999)
Published	25 years, 10 months ago (Nov. 1, 1999)
Published Online	11 years, 3 months ago (May 29, 2014)
Published Print	25 years, 10 months ago (Nov. 1, 1999)

Funders 0

None

BibTeX

@article{Rostom_1999, title={Positron emission tomography in breast cancer: a clinicopathological correlation of results.}, volume={72}, ISSN={0007-1285}, url={http://dx.doi.org/10.1259/bjr.72.863.10700822}, DOI={10.1259/bjr.72.863.10700822}, number={863}, journal={The British Journal of Radiology}, publisher={Oxford University Press (OUP)}, author={Rostom, A Y and Powe, J and Kandil, A and Ezzat, A and Bakheet, S and el-Khwsky, F and el-Hussainy, G and Sorbris, R and Sjoklint, O}, year={1999}, month=nov, pages={1064–1068} }

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