DOI: 10.1259/bjr.70.830.9135440. MRI study of hepatic tumours following high intensity focused ultrasound surgery.

MRI study of hepatic tumours following high intensity focused ultrasound surgery.

10.1259/bjr.70.830.9135440

Crossref journal-article

Oxford University Press (OUP)

The British Journal of Radiology (286)

Abstract

High intensity, focused ultrasound has considerable potential as a non-invasive surgical technique, with applications which include the treatment of benign prostatic hyperplasia and the elimination of metastatic disease in the liver. In this study, the use of MRI for treatment planning and subsequent monitoring of ultrasound therapy in the liver has been evaluated. In an experimental model both tumour bearing and normal liver lobes were treated invasively with high intensity focused beam ultrasound surgery. Subsequent changes in the tissue properties were investigated using MRI, in combination with the intravenous contrast agent, Gd-DTPA. The repair of ultrasound damaged tissue was followed until 8 weeks after treatment. The appearance of the MR images was compared with histological sections prepared from parallel experiments. Imaging and histology results showed excellent agreement, illustrating that MRI is well suited to the non-invasive observation of the effects of high intensity focused ultrasound therapy on tissue. Thus, as the clinical potential of ultrasound surgery is realized, MRI, together with the use of contrast agents, will be invaluable both in treatment planning and in monitoring the progress of a treated tumour.

Authors 7

I J Rowland (first)
I Rivens (additional)
L Chen (additional)
C H Lebozer (additional)
D J Collins (additional)
G R ter Haar (additional)
M O Leach (additional)

References 12 Referenced 78

10.3171/jns.1954.11.5.0471
10.1121/1.1908200
{'key': 'p_3', 'first-page': '387', 'volume': '102', 'author': 'Warwick R', 'year': '1968', 'journal-title': 'J Acoust Soc Am'} / J Acoust Soc Am by Warwick R (1968)
10.1121/1.1912979
10.1001/archsurg.1973.01350240053015
10.1001/archsurg.1991.01410320088012
10.1088/0031-9155/36/11/009
{'key': 'p_8', 'volume-title': 'Proc 10th Meeting SMRM 1991:1257', 'author': 'Rowland IJ'} / Proc 10th Meeting SMRM 1991:1257 by Rowland IJ
{'key': 'p_9', 'first-page': '397', 'volume': '47', 'author': 'North SM', 'year': '1982', 'journal-title': 'Immunology'} / Immunology by North SM (1982)
10.1016/0301-5629(93)90019-K
{'key': 'p_11', 'volume-title': 'Quantitative studies of biological damage induced using high intensity focused ultrasound', 'author': 'Rivens IH.', 'year': '1992'} / Quantitative studies of biological damage induced using high intensity focused ultrasound by Rivens IH. (1992)
{'key': 'p_12', 'volume-title': 'Physical principles of medical ultrasonics.', 'author': 'Haar GR.', 'year': '1986'} / Physical principles of medical ultrasonics. by Haar GR. (1986)

Dates

Type	When
Created	11 years, 2 months ago (June 12, 2014, 9:58 p.m.)
Deposited	1 year, 7 months ago (Jan. 12, 2024, 11:18 a.m.)
Indexed	1 month, 2 weeks ago (July 22, 2025, 6:45 a.m.)
Issued	28 years, 7 months ago (Feb. 1, 1997)
Published	28 years, 7 months ago (Feb. 1, 1997)
Published Online	28 years, 7 months ago (Feb. 1, 1997)
Published Print	28 years, 7 months ago (Feb. 1, 1997)

Funders 0

None

BibTeX

@article{Rowland_1997, title={MRI study of hepatic tumours following high intensity focused ultrasound surgery.}, volume={70}, ISSN={0007-1285}, url={http://dx.doi.org/10.1259/bjr.70.830.9135440}, DOI={10.1259/bjr.70.830.9135440}, number={830}, journal={The British Journal of Radiology}, publisher={Oxford University Press (OUP)}, author={Rowland, I J and Rivens, I and Chen, L and Lebozer, C H and Collins, D J and ter Haar, G R and Leach, M O}, year={1997}, month=feb, pages={144–153} }

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