DOI: 10.1242/jcs.110.24.3043. The AMF-R tubule is a smooth ilimaquinone-sensitive subdomain of the endoplasmic reticulum

The AMF-R tubule is a smooth ilimaquinone-sensitive subdomain of the endoplasmic reticulum

10.1242/jcs.110.24.3043

Crossref journal-article

The Company of Biologists

Journal of Cell Science (237)

Abstract

ABSTRACT Autocrine motility factor receptor (AMF-R) is a marker for a distinct smooth membranous tubule. Ilimaquinone (IQ) is a sea sponge metabolite which induces the complete vesiculation of the Golgi apparatus and we show here that the addition of IQ to MDCK cells also results in the disruption of the AMF-R tubule. By immunofluorescence microscopy, the resultant punctate AMF-R label resembles the products of IQ-mediated vesiculation of the trans-Golgi network, however, the two labels can be distinguished by confocal microscopy. AMF-R tubule fragmentation occurs after nocodazole or taxol treatment of the cells demonstrating that the action of IQ on AMF-R tubules is not related to the ability of IQ to depolymerize microtubules. IQ activity is therefore not Golgi-specific. Electron microscopy of IQ-treated cells reveals that AMF-R is distributed to fenestrated networks of narrow interconnected tubules which are distinguishable from the uniform Golgi-derived vesicles and morphologically equivalent to smooth ER. Distinct fenestrations are visible in incompletely fragmented tubules which may represent intermediates in the fragmentation process. Smooth AMF-R labeled tubules exhibit continuity with rough ER cisternae and IQ selectively targets smooth and not rough ER. AMF-R tubules can be distinguished from the intermediate compartment labeled for ERGIC-53 by confocal microscopy and thus constitute a distinct IQ-sensitive subdomain of the smooth ER.

Bibliography

Wang, H.-J., Benlimame, N., & Nabi, I. R. (1997). The AMF-R tubule is a smooth ilimaquinone-sensitive subdomain of the endoplasmic reticulum. Journal of Cell Science, 110(24), 3043â3053.

Authors 3

Hui-Jun Wang (first)
Naciba Benlimame (additional)
Ivan R. Nabi (additional)

References 50 Referenced 32

10.1016/0092-8674(95)90269-4 / Cell / The formation of Golgi stacks from vesiculated Golgi membranes requires two distinct fusion events by Acharya (1995)
10.1083/jcb.129.3.577 / J. Cell Biol / Reconstitution of vesiculated Golgi membranes into stacks of cisternae: Requirement of NSF in stack formation by Acharya (1995)
10.1083/jcb.129.2.459 / J. Cell Biol / Autocrine motility factor receptor is a marker for a distinct tubular membrane organelle by Benlimame (1995)
10.1016/0955-0674(91)90028-W / Curr. Opin. Cell Biol / Degradation of proteins within the endoplasmic reticulum by Bonifacino (1991)
10.1016/0092-8674(90)90369-P / Cell / Localization of low molecular weight GTP binding proteins to exocytic and endocytic compartments by Chavrier (1990)
10.1091/mbc.7.4.631 / Mol. Biol. Cell / Golgi dispersal during microtubule disruption: Regeneration of Golgi stacks at peripheral endoplasmic reticulum sites by Cole (1996)
10.1083/jcb.110.6.1923 / J. Cell Biol / Studies on the mechanism of autophagy: formation of the autophagic vacuole by Dunn (1990)
10.1083/jcb.110.6.1935 / J. Cell Biol / Studies on the mechanism of autophagy: maturation of the autophagic vacuole by Dunn (1990)
{'key': '2024010622142097300_JOCES_110_24_3043C9', 'volume-title': 'The Cell', 'author': 'Fawcett', 'year': '1981'} / The Cell by Fawcett (1981)
10.1002/j.1460-2075.1985.tb04005.x / EMBO J / Epoxide hydrolase is a marker for the smooth endoplasmic reticulum by Galteau (1985)
10.1126/science.275.5306.1643 / Science / Spatially and functionally distinct Ca2+ stores in sarcoplasmic and endopalsmic reticulum by Golovina (1997)
10.1016/0955-0674(92)90078-Q / Curr. Opin. Cell Biol / The endoplasmic reticulum-Golgi intermediate compartment by Hauri (1992)
10.1083/jcb.108.3.855 / J. Cell Biol / Changes in lysosome shape and distribution correlated with changes in cytoplasmic pH by Heuser (1989)
{'key': '2024010622142097300_JOCES_110_24_3043C14', 'first-page': '250', 'article-title': 'Reclustering of scattered Golgi elements occurs along microtubules', 'volume': '48', 'author': 'Ho', 'year': '1989', 'journal-title': 'Eur. J. Cell Biol'} / Eur. J. Cell Biol / Reclustering of scattered Golgi elements occurs along microtubules by Ho (1989)
10.1083/jcb.118.4.795 / J. Cell Biol / The Rubella virus E1 glycoprotein is arrested in a novel post-ER, pre-Golgi compartment by Hobman (1992)
10.1083/jcb.120.5.1123 / J. Cell Biol / Localization of TGN38 to the trans-Golgi network: Involvement of a cytoplasmic tyrosine-containing sequence by Humphrey (1993)
10.1177/14.3.215 / J. Histochem. Cytochem / Hypertrophy of the agranular endoplasmic reticulum in hamster liver induced by phenobarbitol by Jones (1966)
10.1083/jcb.116.5.1071 / J. Cell Biol / Brefeldin A: insights into the control of membrane traffic and organelle structure by Klausner (1992)
10.1083/jcb.124.1.55 / J. Cell Biol / Characterization of the budding compartment of mouse hepatitis virus: Evidence that transport from the RER to the Golgi complex requires only one vesicular transport step by Krijnse-Locker (1994)
10.1091/mbc.6.10.1315 / Mol. Biol. Cell / The organization of the endoplasmic reticulum and the intermediate compartment in cultured rat hippocampal neurons by Krijnse-Locker (1995)
10.1242/jcs.109.6.1415 / J. Cell Sci / Cell-free assembly of rough and smooth endoplasmic reticulum by Lavoie (1996)
10.1083/jcb.109.5.2045 / J. Cell Biol / Construction of the endoplasmic reticulum by Lee (1989)
10.1083/jcb.109.2.463 / J. Cell Biol / Mitotic Golgi fragments in HeLa cells and their role in the reassembly pathway by Lucocq (1989)
10.1177/002215549704501004 / J. Histochem. Cytochem / AMF-R tubules concentrate in a pericentriolar microtubule domain following transformation of MDCK epithelial cells by Nabi (1997)
{'key': '2024010622142097300_JOCES_110_24_3043C25', 'first-page': '409', 'article-title': 'Identification of B16-F1 melanoma autocrine motility-like factor receptor', 'volume': '50', 'author': 'Nabi', 'year': '1990', 'journal-title': 'Cancer Res'} / Cancer Res / Identification of B16-F1 melanoma autocrine motility-like factor receptor by Nabi (1990)
10.1083/jcb.119.1.85 / J. Cell Biol / A non-autophagic pathway for diversion of ER secretory proteins to lysosomes by Noda (1992)
10.1083/jcb.121.1.49 / J. Cell Biol / β-COP localizes mainly to the cis-Golgi side in exocrine pancreas by Oprins (1993)
10.1016/0092-8674(84)90033-3 / Cell / Increase in membrane cholesterol: A possible trigger for degradation of HMG CoA reductase and crystalloid endoplasmic reticulum in UT-1 cells by Orci (1984)
10.1126/science.1096303 / Science / Intracellular aspects of the process of protein synthesis by Palade (1975)
10.1083/jcb.102.6.2158 / J. Cell Biol / Biogenesis of the crystalloid endoplasmic reticulum in UT-1 cells: Evidence that newly formed endoplasmic reticulum emerges from the nuclear envelope by Pathak (1986)
10.1152/physrev.1994.74.3.595 / Physiol. Rev / Molecular and cellular physiology of intracellular calcium stores by Pozzan (1994)
10.1016/0092-8674(95)90270-8 / Cell / An NSF-like ATPase, p97, and NSF mediate cisternal regrowth from mitotic Golgi fragments by Rabouille (1995)
10.1083/jcb.121.5.1011 / J. Cell Biol / Macropinosome maturation and fusion with tubular lysosomes in macrophages by Racoosin (1993)
10.1091/mbc.5.10.1093 / Mol. Biol. Cell / TGN38 recycles basolaterally in polarized Madin-Darby canine kidney cells by Rajasekaran (1994)
{'key': '2024010622142097300_JOCES_110_24_3043C35', 'first-page': '189', 'article-title': 'Three-dimensional electron microscopy: structure of the Golgi apparatus', 'volume': '51', 'author': 'Rambourg', 'year': '1990', 'journal-title': 'Eur. J. Cell Biol'} / Eur. J. Cell Biol / Three-dimensional electron microscopy: structure of the Golgi apparatus by Rambourg (1990)
10.1083/jcb.131.6.1403 / J. Cell Biol / Misfolded major histocompatibility complex class I molecules accumulate in an expanded ER-Golgi intermediate compartment by Raposo (1995)
10.1083/jcb.102.5.1615 / J. Cell Biol / Unusual lysosomes in aortic smooth muscle cells: presence in living and rapidly frozen cells by Robinson (1986)
10.1083/jcb.99.3.1101 / J. Cell Biol / Effect of microtubule assembly status on the intracellular processing and surface expression of an integral protein of the plasma membrane by Rogalski (1984)
10.1016/S0960-9822(00)00051-8 / Curr. Biol / Implications of the SNARE hypothesis for intracellular membrane topology and dynamics by Rothman (1994)
10.1242/jcs.100.3.415 / J. Cell Sci / Distribution of the intermediate elements operating in ER to Golgi transport by Saraste (1991)
10.1083/jcb.107.5.1643 / J. Cell Biol / Identification, by a monoclonal antibody, of a 53 kD protein associated with a tubulovesicular compartment at the cis-side of the Golgi apparatus by Schweizer (1988)
10.1091/mbc.3.10.1067 / Mol. Biol. Cell / Endoplasmic reticulum: A dynamic patchwork of specialized subregions by Sitia (1992)
10.1083/jcb.42.1.92 / J. Cell Biol / Correlated morphometric and biochemical studies on the liver cell II. Effects of phenobarbitol on rat hepatocytes by Stäubli (1969)
10.1016/0092-8674(93)90638-7 / Cell / Complete vesiculation of Golgi membranes and inhibition of protein transport by a novel sea sponge metabolite, ilimaquinone by Takizawa (1993)
10.1083/jcb.103.4.1557 / J. Cell Biol / Microtubules and the endoplasmic reticulum are highly interdependent structures by Terasaki (1986)
10.1016/S0014-4827(85)80032-X / Exp. Cell Res / Microtubules and the organization of the Golgi complex by Thyberg (1985)
10.1083/jcb.109.5.2081 / J. Cell Biol / The response of the Golgi complex to microtubule alterations: The roles of metabolic energy and membrane traffic in Golgi complex organization by Turner (1989)
10.1083/jcb.122.6.1197 / J. Cell Biol / Microtubule independent vesiculation of Golgi membranes and the reassembly of vesicles into Golgi stacks by Veit (1993)
10.1016/1043-4682(92)90019-R / Semin. Cell Biol / Subcompartments of the endoplasmic reticulum by Vertel (1992)
10.1016/S0092-8674(05)80089-3 / Cell / Golgi membrane dynamics imaged by freeze-etch electron microscopy: Views of different membrane coatings involved in tubulation versus vesiculation by Weidman (1993)

Dates

Type	When
Created	4 years, 3 months ago (April 25, 2021, 12:48 p.m.)
Deposited	1 year, 7 months ago (Jan. 6, 2024, 5:14 p.m.)
Indexed	1 year, 7 months ago (Jan. 13, 2024, 7:44 p.m.)
Issued	27 years, 8 months ago (Dec. 15, 1997)
Published	27 years, 8 months ago (Dec. 15, 1997)
Published Online	27 years, 8 months ago (Dec. 15, 1997)
Published Print	27 years, 8 months ago (Dec. 15, 1997)

Funders 0

None

BibTeX

@article{Wang_1997, title={The AMF-R tubule is a smooth ilimaquinone-sensitive subdomain of the endoplasmic reticulum}, volume={110}, ISSN={1477-9137}, url={http://dx.doi.org/10.1242/jcs.110.24.3043}, DOI={10.1242/jcs.110.24.3043}, number={24}, journal={Journal of Cell Science}, publisher={The Company of Biologists}, author={Wang, Hui-Jun and Benlimame, Naciba and Nabi, Ivan R.}, year={1997}, month=dec, pages={3043–3053} }

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      "journal-title": "Cell"
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      "author": "Benlimame",
      "year": "1995",
      "journal-title": "J. Cell Biol"
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      "journal-title": "Curr. Opin. Cell Biol"
    },
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      "doi-asserted-by": "publisher",
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      "article-title": "Localization of low molecular weight GTP binding proteins to exocytic and endocytic compartments",
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      "author": "Chavrier",
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      "author": "Cole",
      "year": "1996",
      "journal-title": "Mol. Biol. Cell"
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      "volume": "110",
      "author": "Dunn",
      "year": "1990",
      "journal-title": "J. Cell Biol"
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