DOI: 10.1242/dev.127.6.1243. Completion of meiosis in <i>Drosophila</i> oocytes requires transcriptional control by Grauzone, a new zinc finger protein

Completion of meiosis in Drosophila oocytes requires transcriptional control by Grauzone, a new zinc finger protein

10.1242/dev.127.6.1243

Crossref journal-article

The Company of Biologists

Development (237)

Abstract

ABSTRACT Mutations in grauzone or cortex cause abnormal arrest in Drosophila female meiosis. We cloned grauzone and identified it as a C2H2-type zinc finger transcription factor. The grauzone transcript is present in ovaries and at later developmental stages. A Grauzone-GFP fusion protein is functional and localizes to nuclei of both nurse cells and follicle cells during oogenesis. Three lines of evidence indicate that grauzone and cortex interact: reducing cortex function enhanced the grauzone mutant phenotype; cortex transcript abundance is reduced in the absence of grauzone function and Grauzone protein binds to the cortex promoter. These results demonstrate that activation of cortex transcription by grauzone is necessary for the completion of meiosis in Drosophila oocytes, and establish a new pathway that specifically regulates the female meiotic cell cycle.

Bibliography

Chen, B., Harms, E., Chu, T., Henrion, G., & Strickland, S. (2000). Completion of meiosis in Drosophila oocytes requires transcriptional control by Grauzone, a new zinc finger protein. Development, 127(6), 1243â1251.

Authors 5

Bin Chen (first)
Emily Harms (additional)
Tehyen Chu (additional)
Gwénola Henrion (additional)
Sidney Strickland (additional)

References 30 Referenced 29

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10.1093/emboj/18.9.2610 / EMBO J / Joint action of two RNA degradation pathways controls the timing of maternal transcript elimination at the midblastila transition in Drosophila melanogaster by Bashirullah (1999)
10.1016/0092-8674(90)90022-7 / Cell / Real-time visualization of cell cycle-dependent changes in microtubule dynamics in cytoplasmic extracts by Belmont (1990)
10.1111/j.1749-6632.1994.tb52800.x / Annals of New York Academy of Sciences / Sequence-specific DNA recognition by Cys2, His2 zinc fingers by Bernstein (1994)
10.1093/genetics/149.1.157 / Genetics / Mapping of Drosophila mutations using site-specific male recombination by Chen (1998)
10.1128/MCB.17.11.6419 / Mol. Cell. Biol / The Mos pathway regulates cytoplasmic polyadenylation in Xenopus oocytes by De Moor (1997)
10.1016/0925-4773(91)90015-X / Mechanisms Dev / Zinc finger proteins: what we know and what we would like to know by El-Baradi (1991)
10.1002/bies.950190106 / BioEssays / Synthesis and function of Mos: the control switch of vertebrate oocyte meiosis by Gebauer (1997)
10.1038/349132a0 / Nature / Cyclin is degraded by the ubiquitin pathway by Glotzer (1991)
10.1016/S0092-8674(00)80542-5 / Cell / A perfect message: RNA surveillance and nonsense-mediated decay by Hentze (1999)
10.1126/science.275.5304.1311 / Science / APC-mediated proteolysis of Ase1 and the morphogenesis of the mitotic spindle by Juang (1997)
10.1016/0092-8674(95)90338-0 / Cell / A 20S complex containing cdc27 and cdc16 catalyzes the mitosis specific conjugation of ubiquitin to cyclin B by King (1995)
10.1126/science.7694370 / Science / Requirement of tryosine phosphorylation for rapid activation of a DNA binding factor by IL-4 by Kotanides (1993)
10.1242/dev.122.2.579 / Development / Mutations that perturb poly(A)-dependent maternal mRNA activation block the initiation of development by Lieberfarb (1996)
10.1016/0092-8674(95)90322-4 / Cell / Cyclin ubiquitination: the destructive end of mitosis by Murray (1995)
10.1016/S0092-8674(00)80910-1 / Cell / MAP Kinases in Meiosis by Murray (1998)
10.1016/S0888-7543(05)80111-9 / Genomics / A knowledge base for predicting protein localization sites in eukaryotic cells by Nakai (1992)
10.1242/jcs.109.7.1707 / J. Cell Science / The Drosophila genes grauzone and cortex are necessary for proper female meiosis by Page (1996)
10.1038/335683a0 / Nature / How eukarotic transcriptional activators work by Ptashne (1988)
10.1002/bies.950190105 / BioEssays / What does Mos do in oocytes and somatic cells? by Sagata (1997)
10.1126/science.7801127 / Science / Coordinate initiation of Drosophila development by regulated polyadenylation of maternal mRNAs by Sallés (1994)
10.1093/genetics/121.1.101 / Genetics / Female-sterile mutations on the second chromosome of Drosophila melanogaster: I. Maternal effect mutations by Schüpbach (1989)
{'key': '2023051200191569000_DEVELOP_127_6_1243C23', 'first-page': '175', 'article-title': 'P element-mediated transformation', 'volume-title': 'Drosophila: A Practical Approach', 'author': 'Spradling', 'year': '1986'} / Drosophila: A Practical Approach / P element-mediated transformation by Spradling (1986)
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10.1038/369400a0 / Nature / Implications for bcd mRNA localization from spatial distribution of exu protein in Drosophila oogenesis by Wang (1994)
{'key': '2023051200191569000_DEVELOP_127_6_1243C28', 'first-page': '411', 'article-title': 'Translational control of developmental decisions', 'volume-title': 'Translational Control', 'author': 'Wickens', 'year': '1996'} / Translational Control / Translational control of developmental decisions by Wickens (1996)
10.1091/mbc.7.5.791 / Mol. Biol. Cell / TPR proteins required for anaphase progression mediate ubiquitination of mitotic B-type cyclins in yeast by Zachariae (1996)
{'key': '2023051200191569000_DEVELOP_127_6_1243C30', 'first-page': '61', 'article-title': 'Using rapid amplification of cDNA ends (RACE) to obtain full-length cDNAs', 'volume-title': 'Methods in Molecular Biology, Vol69: cDNA libray Protocols', 'author': 'Zhang', 'year': '1997'} / Methods in Molecular Biology, Vol69: cDNA libray Protocols / Using rapid amplification of cDNA ends (RACE) to obtain full-length cDNAs by Zhang (1997)

Dates

Type	When
Created	4 years, 4 months ago (April 23, 2021, 3:59 p.m.)
Deposited	2 years, 3 months ago (May 11, 2023, 8:19 p.m.)
Indexed	1 year ago (Aug. 4, 2024, 7:16 p.m.)
Issued	25 years, 5 months ago (March 15, 2000)
Published	25 years, 5 months ago (March 15, 2000)
Published Online	25 years, 5 months ago (March 15, 2000)
Published Print	25 years, 5 months ago (March 15, 2000)

Funders 0

None

BibTeX

@article{Chen_2000, title={Completion of meiosis in Drosophila oocytes requires transcriptional control by Grauzone, a new zinc finger protein}, volume={127}, ISSN={1477-9129}, url={http://dx.doi.org/10.1242/dev.127.6.1243}, DOI={10.1242/dev.127.6.1243}, number={6}, journal={Development}, publisher={The Company of Biologists}, author={Chen, Bin and Harms, Emily and Chu, Tehyen and Henrion, Gwénola and Strickland, Sidney}, year={2000}, month=mar, pages={1243–1251} }

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  "URL": "http://dx.doi.org/10.1242/dev.127.6.1243",
  "relation": {},
  "ISSN": [
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    "1477-9129"
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  "subject": [],
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        3,
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}