DOI: 10.1242/dev.121.3.785. Analysis of the genetic hierarchy guiding wing vein development in <i>Drosophila</i>

Analysis of the genetic hierarchy guiding wing vein development in Drosophila

10.1242/dev.121.3.785

Crossref journal-article

The Company of Biologists

Development (237)

Abstract

ABSTRACT The Drosophila rhomboid (rho) and Egf- and r genes are members of a small group of genes required for the differ- and entiation of various specific embryonic and adult structures. During larval and early pupal development expression of rho in longitudinal vein primordia mediates the localized formation of wing veins. In this paper we investigate the genetic hierarchy guiding vein development, by testing for genetic interactions between rho alleles and a wide variety of wing vein mutations and by examining the pattern of rho expression in mutant developing wing primordia. We identify a small group of wing vein mutants that interact strongly with rho. Examination of rho expression in these and other key vein mutants reveals when vein development first becomes abnormal. Based on these data and on previous genetic analyses of vein formation we present a sequential model for establishment and differentiation of wing veins.

Bibliography

Sturtevant, M. A., & Bier, E. (1995). Analysis of the genetic hierarchy guiding wing vein development in Drosophila. Development, 121(3), 785â801.

Authors 2

Mark A. Sturtevant (first)
Ethan Bier (additional)

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Dates

Type	When
Created	4 years, 4 months ago (April 25, 2021, 10:09 p.m.)
Deposited	7 months, 3 weeks ago (Jan. 15, 2025, 8:46 a.m.)
Indexed	4 weeks, 1 day ago (Aug. 7, 2025, 4:37 p.m.)
Issued	30 years, 6 months ago (March 1, 1995)
Published	30 years, 6 months ago (March 1, 1995)
Published Online	30 years, 6 months ago (March 1, 1995)
Published Print	30 years, 6 months ago (March 1, 1995)

Funders 0

None

BibTeX

@article{Sturtevant_1995, title={Analysis of the genetic hierarchy guiding wing vein development in Drosophila}, volume={121}, ISSN={1477-9129}, url={http://dx.doi.org/10.1242/dev.121.3.785}, DOI={10.1242/dev.121.3.785}, number={3}, journal={Development}, publisher={The Company of Biologists}, author={Sturtevant, Mark A. and Bier, Ethan}, year={1995}, month=mar, pages={785–801} }

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