DOI: 10.1242/dev.110.3.915. Isolation of an <i>abdominal-A</i> gene from the locust <i>Schistocerca gregaria</i> and its expression during early embryogenesis

Isolation of an abdominal-A gene from the locust Schistocerca gregaria and its expression during early embryogenesis

10.1242/dev.110.3.915

Crossref journal-article

The Company of Biologists

Development (237)

Abstract

Abstract Using sequence homology to Drosophila homeobox-containing genes, we have cloned a homologue of abdominal-A from the locust Schistocerca gregaria. The Schistocerca clone encodes a stretch of 78 amino acids including the homeodomain and its flanking regions identical to the corresponding region of abdominal-A. We have shown by in situ hybridization that this gene is transcribed and have used an antibody raised against its protein product to examine the expression of abdominal-A during early Schistocerca embryogenesis. Schistocerca is a short germ insect. Although the segmented body plan is very similar to that of Drosophila, the segments are generated sequentially by a process of growth, not simultaneously by subdivision of a syncytial blastoderm. In both organisms, abdominal-A is expressed throughout the abdomen from a sharp anterior boundary located within the first abdominal segment (Al). The initial activation of the genes in the two species differs. Schistocerca initiates expression in a small group of cells in the anterior of A2, shortly after this segment is defined by the appearance of engrailed protein. This contrasts with the appearance of abdominal-A expression in Drosophila, which appears simultaneously throughout the entire abdomen.

Bibliography

Tear, G., Akam, M., & Martinez-Arias, A. (1990). Isolation of an abdominal-A gene from the locust Schistocerca gregaria and its expression during early embryogenesis. Development, 110(3), 915â925.

Authors 3

Guy Tear (first)
Michael Akam (additional)
Alfonso Martinez-Arias (additional)

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Dates

Type	When
Created	4 years, 4 months ago (April 25, 2021, 9:38 p.m.)
Deposited	1 year, 1 month ago (July 10, 2024, 3:25 a.m.)
Indexed	1 month, 1 week ago (July 22, 2025, 7:12 a.m.)
Issued	34 years, 10 months ago (Nov. 1, 1990)
Published	34 years, 10 months ago (Nov. 1, 1990)
Published Online	34 years, 10 months ago (Nov. 1, 1990)
Published Print	34 years, 10 months ago (Nov. 1, 1990)

Funders 0

None

BibTeX

@article{Tear_1990, title={Isolation of an abdominal-A gene from the locust Schistocerca gregaria and its expression during early embryogenesis}, volume={110}, ISSN={1477-9129}, url={http://dx.doi.org/10.1242/dev.110.3.915}, DOI={10.1242/dev.110.3.915}, number={3}, journal={Development}, publisher={The Company of Biologists}, author={Tear, Guy and Akam, Michael and Martinez-Arias, Alfonso}, year={1990}, month=nov, pages={915–925} }

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