DOI: 10.1212/wnl.46.1.231. [sup 123 I] beta-CIT/SPECT imaging demonstrates bilateral loss of dopamine transporters in hemi-Parkinson's disease

[sup 123 I] beta-CIT/SPECT imaging demonstrates bilateral loss of dopamine transporters in hemi-Parkinson's disease

10.1212/wnl.46.1.231

Crossref journal-article

Ovid Technologies (Wolters Kluwer Health)

Neurology (276)

Bibliography

Marek, K. L., Seibyl, J. P., Zoghbi, S. S., Zea-Ponce, Y., Baldwin, R. M., Fussell, B., Charney, D. S., van Dyck, C., Hoffer, P. B., & Innis, R. B. (1996). [sup 123 I] beta-CIT/SPECT imaging demonstrates bilateral loss of dopamine transporters in hemi-Parkinsonâs disease. Neurology, 46(1), 231â237.

Authors 10

K. L. Marek (first)
J. P. Seibyl (additional)
S. S. Zoghbi (additional)
Y. Zea-Ponce (additional)
R. M. Baldwin (additional)
B. Fussell (additional)
D. S. Charney (additional)
C. van Dyck (additional)
P. B. Hoffer (additional)
R. B. Innis (additional)

References 42 Referenced 281

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McGeer PL, Itagaki S, Akiyama S, McGeer EG. Rate of cell death in parkinsonism indicates active neuropathological process. Ann Neurol 1988;24:574-576. / Ann Neurol (1988)
Golbe L. The genetics of Parkinson's disease: a reconsideration. Neurology 1990;40:7-16. / Neurology (1990)
Bernbeimer H, Birkmayer W, Hornykiewicz O, Jellinger K, Seitleberger F. Brain dopamine and the syndromes of Parkinson and Huntington, clinical, morphological, and neurochemical correlates. J Neurol Sci 1973;20:415-455. / J Neurol Sci (1973)
Lees AJ. When did Ray Kennedy's Parkinson's disease begin? Mov Disord 1992;7:110-116. / When did Ray Kennedy's Parkinson's disease begin? Mov Disord (1992)
Hoehn MM, Yahr MD. Parkinsonism: onset, progression and mortality. Neurology 1967;17:427-442. / Neurology (1967)
10.1097/00005053-190401000-00001
Watts RL Mandir AS Ahn KJ Juncos JL Zakers GO Freeman A. Electrophysiologic analysis of early Parkinson's disease. Neurology 1991;41(suppl 2):44-48. (10.1212/WNL.41.5_Suppl_2.44)
Nahmias C, Garnett ES, Firnau G, Lang A. Striatal dopamine distribution in parkinsonian patients during life. J Neurol Sci 1985;69:223-230. / J Neurol Sci (1985)
Otsuka M, Ichiya Y, Hosokawa S, et al. Striatal blood flow, glucose metabolism, and sup 18 F-Dopa uptake: difference in Parkinson's disease and atypical parkinsonism. J Neurol Neurosurg Psychiatry 1991;54:898-904. / J Neurol Neurosurg Psychiatry (1991)
Brooks DJ, Ibanez V, Sawle G, et al. Differing patterns of sup 18 F-Dopa uptake in Parkinson's disease, multiple system atrophy, and progressive supranuclear palsy. Ann Neurol 1990;28:547-555. / Ann Neurol (1990)
Sawle GV. The detection of preclinical Parkinson's disease: what is the role of positron emission tomography? Mov Disord 1993;8:271-277. / The detection of preclinical Parkinson's disease: what is the role of positron emission tomography? Mov Disord (1993)
Snow BJ, Peppard RF, Guttman M, Calne DB. Positron emission tomographic scanning demonstrates a presynaptic dopaminergic lesion in Lytico-Bodig. Arch Neurol 1990;47:870-874. / Arch Neurol (1990)
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10.1212/WNL.42.1.1
Uhl GR. Neurotransmitter transporters (plus): a promising new gene family. Trends Neurosci 1992;15:265-268. / Trends Neurosci (1992)
Leenders K, Salmon EP, Tyrrell P, et al. The nigrostriatal dopaminergic system assessed in vivo by positron emission tomography in healthy volunteer subjects and patients with Parkinson's disease. Arch Neurol 1990;47:1290-1298. / Arch Neurol (1990)
Neumeyer JL, Wang S, Milius RA, et al. [sup 123 I]-2-beta-Carbomethoxy-3-beta-(4-iodophenyl)-tropane (beta-CIT): high affinity SPECT radiotracer of monoamine reuptake sites in brain. J Med Chem 1991;34:3144-3146. / J Med Chem (1991)
Kaufman MJ, Madras BK. Severe depletion of cocaine recognition sites associated with the dopamine transporter in Parkinson's diseased striatum. Synapse 1991;9:43-49. / Synapse (1991)
10.1002/syn.890100102
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Langston JW, Widner H, Goetz CG, et al. Core assessment program for intracerebral transplantations (CAPIT). Mov Disord 1992;7:2-13. / Mov Disord (1992)
Baldwin RM, Zea-Ponce Y, Zoghbi SS, et al. Evaluation of the monoamine uptake site ligand [sup 123 I]methyl 3 beta-(4-iodophenyl) tropane-2 beta-carboxylate ([sup 123 I] beta-CIT) in nonhuman primates: pharmacokinetics, biodistribution, and SPECT brain imaging coregistered with MRI. Nucl Med Biol 1993;20:597-606. / Nucl Med Biol (1993)
Holman BL, Carvalho PA, Zimmerman RE, et al. Brain perfusion SPECT using an annular single crystal camera: initial clinical experience. J Nucl Med 1990;31:1456-1461. / J Nucl Med (1990)
Chang LT. A method for attenuation correction in computed tomography. IEEE Trans Nucl Sci 1987;25:638-643. / IEEE Trans Nucl Sci (1987)
Laruelle M, Wallace E, Seibyl JP, et al. Graphical, kinetic, and equilibrium analyses of in vivo [sup 123 I] beta-CIT binding to dopamine transporters in healthy human subjects. J Cereb Blood Flow Metab 1994;14:982-994. / J Cereb Blood Flow Metab (1994)
Fang J, Yu PH. Effect of L-deprenyl, its structural analogues and some mono-amine oxidase inhibitors on dopamine uptake. Neuropharmacology 1994;33:763-768. / Neuropharmacology (1994)
van Dyck CH Seibyl JP Malison RT et al. Age-related decline in dopamine transporter binding in human striatum with [sup 123 I] beta-CIT SPECT. J Nucl Med (in press).
10.1002/ana.410360703
Vingerhoets FJG, Snow BJ, Lee CS, Schulzer M, Mak E, Calne DB. Longitudinal fluorodopa positron emission tomographic studies of the evolution of idiopathic parkinsonism. Ann Neurol 1994;36:759-764. / Ann Neurol (1994)
Scherman D, Desnons C, Darchen F, Pollak P, Javoy-Agid F, Agid Y. Striatal dopamine deficiency in Parkinson's disease: role of aging. Ann Neurol 1989;26:551-557. / Ann Neurol (1989)
Sawle GV, Colebatch JG, Shah A, Brooks DJ, Marsden CD, Frackowiak RJS. Striatal function in normal aging-implications for Parkinson's disease. Ann Neurol 1990;28:799-804. / Ann Neurol (1990)
Kish SJ, Shannak K, Hornykiewicz O. Uneven pattern of dopamine loss in the stratum of patients with idiopathic Parkinson's disease. N Engl J Med 1988;318:876-880. / N Engl J Med (1988)
Fearnley JM, Lees AJ. Ageing and Parkinson's disease: substantia nigra regional selectivity. Brain 1991;114:2283-2301. / Brain (1991)
Calne DB. Is idiopathic parkinsonism the consequence of an event or a process? Neurology 1993;44:5-10. / Is idiopathic parkinsonism the consequence of an event or a process? Neurology (1993)
Lee CS, Schulzer M, Mak EK, et al. Clinical observations on the rate of progression of idiopathic parkinsonism. Brain 1994;117:501-507. / Brain (1994)
Eidelberg D, Moeller JR, Dhawan V, et al. The metabolic anatomy of Parkinson's disease complementary [18F]fluorodeoxyglucose and [18F]fluorodopa positron emission tomographic studies. Mov Disord 1990;5:203-213. / Mov Disord (1990)
10.1016/0022-510X(93)90061-3

Dates

Type	When
Created	13 years, 3 months ago (May 13, 2012, 9:17 a.m.)
Deposited	1 year, 5 months ago (March 27, 2024, 9:40 a.m.)
Indexed	1 week, 1 day ago (Aug. 29, 2025, 5:53 a.m.)
Issued	29 years, 8 months ago (Jan. 1, 1996)
Published	29 years, 8 months ago (Jan. 1, 1996)
Published Print	29 years, 8 months ago (Jan. 1, 1996)

Funders 0

None

BibTeX

@article{Marek_1996, title={[sup 123 I] beta-CIT/SPECT imaging demonstrates bilateral loss of dopamine transporters in hemi-Parkinson’s disease}, volume={46}, ISSN={1526-632X}, url={http://dx.doi.org/10.1212/wnl.46.1.231}, DOI={10.1212/wnl.46.1.231}, number={1}, journal={Neurology}, publisher={Ovid Technologies (Wolters Kluwer Health)}, author={Marek, K. L. and Seibyl, J. P. and Zoghbi, S. S. and Zea-Ponce, Y. and Baldwin, R. M. and Fussell, B. and Charney, D. S. and van Dyck, C. and Hoffer, P. B. and Innis, R. B.}, year={1996}, month=jan, pages={231–237} }

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