DOI: 10.1189/jlb.0205074. Nanotechnology for the biologist

10.1189/jlb.0205074

Crossref journal-article

Oxford University Press (OUP)

Journal of Leukocyte Biology (286)

Abstract

AbstractNanotechnology refers to research and technology development at the atomic, molecular, and macromolecular scale, leading to the controlled manipulation and study of structures and devices with length scales in the 1- to 100-nanometers range. Objects at this scale, such as “nanoparticles,” take on novel properties and functions that differ markedly from those seen in the bulk scale. The small size, surface tailorability, improved solubility, and multifunctionality of nanoparticles open many new research avenues for biologists. The novel properties of nanomaterials offer the ability to interact with complex biological functions in new ways—operating at the very scale of biomolecules. This rapidly growing field allows cross-disciplinary researchers the opportunity to design and develop multifunctional nanoparticles that can target, diagnose, and treat diseases such as cancer. This article presents an overview of nanotechnology for the biologist and discusses “nanotech” strategies and constructs that have already demonstrated in vitro and in vivo efficacy.

Bibliography

McNeil, S. E. (2005). Nanotechnology for the biologist. Journal of Leukocyte Biology, 78(3), 585â594.

Authors 1

Scott E McNeil (first)

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Dates

Type	When
Created	20 years, 3 months ago (May 27, 2005, 10:05 p.m.)
Deposited	1 year, 7 months ago (Jan. 26, 2024, 1:12 a.m.)
Indexed	2 days, 19 hours ago (Sept. 3, 2025, 7:17 a.m.)
Issued	20 years, 3 months ago (May 27, 2005)
Published	20 years, 3 months ago (May 27, 2005)
Published Online	20 years, 3 months ago (May 27, 2005)
Published Print	20 years, 3 months ago (May 27, 2005)

Funders 2

National Cancer Institute 10.13039/100000054
Region: Americas
gov (National government)
Labels4
1. Instituto Nacional del Cáncer
2. National Cancer Institute at the National Institutes of Health
3. Instituto Nacional del Cáncer de los Institutos Nacionales de la Salud
4. NCI
National Institutes of Health 10.13039/100000002
Region: Americas
gov (National government)
Labels3
1. Institutos Nacionales de la Salud
2. US National Institutes of Health
3. NIH
Awards1
1. N01-C0-12400

BibTeX

@article{McNeil_2005, title={Nanotechnology for the biologist}, volume={78}, ISSN={1938-3673}, url={http://dx.doi.org/10.1189/jlb.0205074}, DOI={10.1189/jlb.0205074}, number={3}, journal={Journal of Leukocyte Biology}, publisher={Oxford University Press (OUP)}, author={McNeil, Scott E}, year={2005}, month=may, pages={585–594} }

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  "abstract": "<jats:title>Abstract</jats:title><jats:p>Nanotechnology refers to research and technology development at the atomic, molecular, and macromolecular scale, leading to the controlled manipulation and study of structures and devices with length scales in the 1- to 100-nanometers range. Objects at this scale, such as \u201cnanoparticles,\u201d take on novel properties and functions that differ markedly from those seen in the bulk scale. The small size, surface tailorability, improved solubility, and multifunctionality of nanoparticles open many new research avenues for biologists. The novel properties of nanomaterials offer the ability to interact with complex biological functions in new ways\u2014operating at the very scale of biomolecules. This rapidly growing field allows cross-disciplinary researchers the opportunity to design and develop multifunctional nanoparticles that can target, diagnose, and treat diseases such as cancer. This article presents an overview of nanotechnology for the biologist and discusses \u201cnanotech\u201d strategies and constructs that have already demonstrated in vitro and in vivo efficacy.</jats:p>",
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