DOI: 10.1177/1087057111414878. Machine Learning Improves the Precision and Robustness of High-Content Screens: Using Nonlinear Multiparametric Methods to Analyze Screening Results

Machine Learning Improves the Precision and Robustness of High-Content Screens: Using Nonlinear Multiparametric Methods to Analyze Screening Results

10.1177/1087057111414878

Crossref journal-article

Elsevier BV

SLAS Discovery (78)

Bibliography

Horvath, P., Wild, T., Kutay, U., & Csucs, G. (2011). Machine Learning Improves the Precision and Robustness of High-Content Screens: Using Nonlinear Multiparametric Methods to Analyze Screening Results. SLAS Discovery, 16(9), 1059â1067.

Authors 4

Peter Horvath (first)
Thomas Wild (additional)
Ulrike Kutay (additional)
Gabor Csucs (additional)

References 16 Referenced 56

10.1038/nature07207 / Nature / RNA Interference Screen for Human Genes Associated with West Nile Virus Infection by Krishnan (2008)
{'key': '10.1177/1087057111414878_bib2', 'series-title': 'The Elements of Statistical Learning', 'author': 'Hastie', 'year': '2001'} / The Elements of Statistical Learning by Hastie (2001)
{'key': '10.1177/1087057111414878_bib3', 'series-title': 'Pattern Classification', 'author': 'Duda', 'year': '2000'} / Pattern Classification by Duda (2000)
10.1186/1471-2105-11-30 / BMC Bioinformatics / Enhanced CellClassifier: A Multi-Class Classification Tool for Microscopy Images by Misselwitz (2010)
10.1093/bioinformatics/btp524 / Bioinformatics / CellClassifier: Supervised Learning of Cellular Phenotypes by Ramo (2009)
10.1186/1471-2105-9-482 / BMC Bioinformatics / CellProfiler Analyst: Data Exploration and Analysis Software for Complex Image-Based Screens by Jones (2008)
10.1177/108705719900400206 / J. Biomol. Screen. / A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays by Zhang (1999)
10.1177/1087057109351311 / J. Biomol. Screen. / Integration of Multiple Readouts into the Z′ Factor for Assay Quality Assessment by Kummel (2010)
10.1016/S0962-8924(03)00054-0 / Trends Cell Biol. / Pre-Ribosomes on the Road from the Nucleolus to the Cytoplasm by Tschochner (2003)
10.1371/journal.pbio.1000522 / PLoS Biol. / A Protein Inventory of Human Ribosome Biogenesis Reveals an Essential Function of Exportin 5 in 60S Subunit Export by Wild (2010)
10.1083/jcb.200904048 / J. Cell. Biol. / Distinct Cytoplasmic Maturation Steps of 40S Ribosomal Subunit Precursors Require hRio2 by Zemp (2009)
10.1186/gb-2006-7-10-r100 / Genome Biol. / CellProfiler: Image Analysis Software for Identifying and Quantifying Cell Phenotypes by Carpenter (2006)
{'key': '10.1177/1087057111414878_bib13', 'series-title': 'Data Mining: Practical Machine Learning Tools and Techniques', 'author': 'Witten', 'year': '2005'} / Data Mining: Practical Machine Learning Tools and Techniques by Witten (2005)
John, G. H. Langley, P. Estimating Continuous Distributions in Bayesian Classifiers. In Proceedings of the Eleventh Conference on Uncertainty in Artificial Intelligence; Morgan Kaufmann: San Mateo, CA, 1995, pp 338–345.
10.1016/j.patrec.2005.10.010 / Pattern Recogn. Lett. / An Introduction to ROC Analysis by Fawcett (2006)
10.1177/1087057110377497 / J. Biomol. Screen. / Experimental Design and Statistical Methods for Improved Hit Detection in High-Throughput Screening by Malo (2010)

Dates

Type	When
Created	14 years, 1 month ago (Aug. 1, 2011, 11:12 p.m.)
Deposited	2 years, 9 months ago (Nov. 19, 2022, 12:40 p.m.)
Indexed	2 months, 4 weeks ago (June 4, 2025, 11:29 a.m.)
Issued	13 years, 11 months ago (Oct. 1, 2011)
Published	13 years, 11 months ago (Oct. 1, 2011)
Published Print	13 years, 11 months ago (Oct. 1, 2011)

Funders 0

None

BibTeX

@article{Horvath_2011, title={Machine Learning Improves the Precision and Robustness of High-Content Screens: Using Nonlinear Multiparametric Methods to Analyze Screening Results}, volume={16}, ISSN={2472-5552}, url={http://dx.doi.org/10.1177/1087057111414878}, DOI={10.1177/1087057111414878}, number={9}, journal={SLAS Discovery}, publisher={Elsevier BV}, author={Horvath, Peter and Wild, Thomas and Kutay, Ulrike and Csucs, Gabor}, year={2011}, month=oct, pages={1059–1067} }

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