Crossref journal-article
SAGE Publications
The Neuroscientist (179)
Abstract

Apoptosis is a form of cellular suicide in which the cell activates an intrinsic program to bring about its own demise. Recognized for years as the mechanism by which developing cells are lost naturally, it has become apparent recently that this same process may play an important role in many acute and chronic diseases in which neural cell death occurs, such as stroke and Alzheimer's disease. This growing recognition suggests that a knowledge of the gene products controlling this process may lead to improved treatments for some disease states, as well as to improved understanding of neuronal development, physiology, and pathophysiology. Some controls with important roles in neural apoptosis have been identified, and these controls, as well as their putative mechanisms of action, are described in this article. NEUROSCIENTIST 2:181-190, 1996

Bibliography

Bredesen, D. E. (1996). REVIEW ■ : Keeping Neurons Alive: The Molecular Control of Apoptosis (Part I. The Neuroscientist, 2(3), 181–190.

Authors 1
  1. Dale E. Bredesen (first)
References 117 Referenced 24
  1. 10.1111/j.1469-185X.1951.tb00774.x
  2. 10.1016/0022-1910(64)90034-4
  3. 10.1016/0012-1606(66)90050-9
  4. 10.1038/bjc.1972.33
  5. 10.1038/348334a0
  6. 10.1126/science.1962198
  7. 10.1128/JVI.66.9.5525-5533.1992
  8. 10.1016/0167-5699(91)90092-8
  9. {'key': 'atypb9', 'first-page': '529', 'volume': '312', 'author': 'Gougeon ML', 'year': '1991', 'journal-title': 'CR Acad Sci'} / CR Acad Sci by Gougeon ML (1991)
  10. 10.1038/342021a0 / Nature by Liu YJ (1989)
  11. Kerr Jfr, Harmon BV Definition and incidence of apoptosis: an historical perspective. In: Tomei LD, FO Cope, editors. Apoptosis : the molecular basis of cell death. Plainview, NY: Cold Spring Harbor Laboratory Press 1991;5-29.
  12. 10.1111/j.1365-2184.1991.tb01150.x
  13. 10.1073/pnas.91.14.6501
  14. 10.1073/pnas.90.3.853
  15. 10.1016/0006-2952(88)90691-0
  16. 10.1016/0003-9861(88)90593-0
  17. 10.4049/jimmunol.148.7.2207
  18. 10.1038/284555a0
  19. McConkey DJ, Orremus S. Cellular signaling in thymocyte apoptosis. In: Tomei LD, FO Cope, editors. Apoptosis: the molecular basis of cell death. Plamview, NY: Cold Spring Harbor Laboratory Press 1991;227-246.
  20. 10.1083/jcb.115.2.461
  21. 10.1016/S0021-9258(18)55102-4
  22. Tomei LD Apoptosis: a program for death or survival? In: Tomei LD, FO Cope, editors. Apoptosis: the molecular basis of cell death. Plainview, NY: Cold Spring Harbor Laboratory Press , 1991;297-316.
  23. Buttyan R. Genetic response of prostate cells to androgen deprivation: insights into the cellular mechanism of apoptosis. In: Tomei LD, FO Cope, editors. Apoptosis: the molecular basis of cell death. Plainview, NY: Cold Spring Harbor Laboratory Press , 1991;157-173.
  24. 10.1073/pnas.86.18.7260
  25. 10.1126/science.2118682
  26. 10.1002/neu.480230911
  27. 10.1016/0014-5793(87)80430-1
  28. 10.1016/0014-5793(89)80210-8
  29. Piacentini M. , Davies Pja, Fesus L. Tissue transglutaminase in cells undergoing apoptosis. In: Tomei LD , FO Cope, editors. Apoptosis: the molecular basis of apoptosis in disease. Plamview, NY: Cold Spring Harbor Laboratory Press , 1994;143-163.
  30. 10.1128/MCB.11.8.4177
  31. 10.1083/jcb.127.6.1717
  32. 10.1016/0896-6273(94)90276-3
  33. 10.1016/0092-8674(93)90485-9
  34. 10.1016/0092-8674(94)90506-1
  35. 10.1016/0012-1606(90)90174-H
  36. 10.1038/356768a0
  37. 10.1126/science.1373520
  38. 10.1016/0092-8674(95)90422-0
  39. 10.1126/science.7535475
  40. 10.1038/371346a0
  41. 10.1073/pnas.93.5.2234
  42. 10.1016/0166-2236(85)90175-4
  43. 10.1126/science.8332899
  44. 10.1073/pnas.91.22.10703
  45. 10.1016/0092-8674(86)90619-7
  46. 10.1038/325593a0
  47. 10.1016/0092-8674(94)90372-7
  48. 10.1073/pnas.88.10.4372
  49. {'volume-title': 'Is GP120 peptide identity with FAS relevant to AIDS pathogenesis', 'year': '1993', 'author': 'Zagury J-F.', 'key': 'atypb49'} / Is GP120 peptide identity with FAS relevant to AIDS pathogenesis by Zagury J-F. (1993)
  50. 10.1073/pnas.72.9.3666
  51. 10.1016/S0021-9258(18)82075-0
  52. 10.1016/0092-8674(93)90464-2
  53. 10.1016/0014-5793(95)01113-S
  54. {'volume-title': 'Structural and functional evidence for a p75NTR death domain', 'author': 'Rabizadeh S.', 'key': 'atypb54'} / Structural and functional evidence for a p75NTR death domain by Rabizadeh S.
  55. 10.1016/0092-8674(95)90071-3
  56. 10.1016/0092-8674(95)90070-5
  57. 10.1074/jbc.270.14.7795
  58. 10.1016/0092-8674(95)90072-1
  59. 10.1126/science.8456305
  60. 10.1073/pnas.91.1.73
  61. 10.1126/science.8079174
  62. 10.1038/368193a0
  63. 10.1016/0014-5793(90)80437-N
  64. 10.1016/S0021-9258(18)77284-0
  65. 10.1016/0014-5793(93)81382-A
  66. 10.1523/JNEUROSCI.11-08-02552.1991
  67. 10.1159/000112108
  68. 10.1038/350678a0
  69. 10.1002/cne.903080405
  70. {'key': 'atypb70', 'first-page': '5403', 'volume': '52', 'author': 'Pflug BR', 'year': '1992', 'journal-title': 'Cancer Res'} / Cancer Res by Pflug BR (1992)
  71. 10.1016/0092-8674(93)90509-O
  72. 10.1038/352345a0
  73. 10.1038/362847a0
  74. 10.1016/0092-8674(95)90412-3
  75. 10.1038/359554a0
  76. 10.1038/359552a0
  77. 10.1046/j.1471-4159.1995.65062432.x
  78. 10.1038/361365a0
  79. 10.1016/0092-8674(93)80066-N
  80. Bredesen DE Neuronal apoptosis: genetic and biochemical modulation. Apoptosis II: The molecular basis of apoptosis in disease. Plainview, NY ; Cold Spring Harbor Laboratory Press 1994: 397-421.
  81. 10.1111/j.1432-0436.1991.tb00880.x
  82. 10.1073/pnas.92.7.3024
  83. 10.1016/0092-8674(95)90461-1
  84. 10.1128/JVI.67.4.2168-2174.1993
  85. 10.1016/S0079-6123(08)61151-6
  86. 10.1161/01.STR.24.12.2002
  87. 10.1038/362543a0
  88. 10.1016/0304-3940(89)90391-1
  89. 10.1111/j.1365-2990.1995.tb01052.x
  90. 10.1073/pnas.92.8.3411
  91. {'key': 'atypb91', 'first-page': '1045', 'volume': '146', 'author': 'Li Y.', 'year': '1995', 'journal-title': 'Am J Pathol'} / Am J Pathol by Li Y. (1995)
  92. {'volume-title': 'Satellite Symposium on Neuronal Apoptosis', 'author': 'Cotman C.', 'key': 'atypb92'} / Satellite Symposium on Neuronal Apoptosis by Cotman C.
  93. 10.1046/j.1471-4159.1994.63051987.x
  94. 10.1523/JNEUROSCI.15-05-03775.1995
  95. 10.1016/0092-8674(93)90508-N
  96. 10.1073/pnas.90.8.3516
  97. 10.1128/JVI.65.11.5991-6000.1991
  98. 10.1101/gad.8.14.1613
  99. 10.1016/S0092-8674(94)90422-7
  100. 10.1002/j.1460-2075.1995.tb07183.x
  101. {'key': 'atypb101', 'first-page': '2737', 'volume': '55', 'author': 'Fernandes-Alnemri T.', 'year': '1995', 'journal-title': 'Cancer Res'} / Cancer Res by Fernandes-Alnemri T. (1995)
  102. 10.1016/0092-8674(95)90541-3
  103. 10.1016/S0021-9258(18)47344-9
  104. 10.1084/jem.176.6.1521
  105. 10.1084/jem.178.5.1693
  106. 10.1016/0092-8674(89)90944-6
  107. 10.1126/science.8171323
  108. {'key': 'atypb108', 'first-page': '245', 'author': 'Trauth BC', 'year': '1989', 'journal-title': 'Science'} / Science by Trauth BC (1989)
  109. 10.1126/science.8171319
  110. 10.1126/science.7536343
  111. 10.1126/science.8303301
  112. 10.1128/MCB.12.6.2570
  113. 10.1083/jcb.129.4.1103
  114. 10.1126/science.271.5248.515
  115. Wong Ghw, Kamb A., Tartaglia LA, Goeddel DV Possible protective mechanisms of tumor necrosis factors against oxidative stress. In: Scandalios JG, editor. Current communications in cell and molecular biology: molecular biology of free radical scavengmg systems. Vol. 5. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press 1992;69.
  116. {'key': 'atypb116', 'first-page': '5314', 'volume': '53', 'author': 'Mangeney M.', 'year': '1993', 'journal-title': 'Cancer Res'} / Cancer Res by Mangeney M. (1993)
  117. 10.1084/jem.180.2.525
Dates
Type When
Created 18 years, 5 months ago (March 11, 2007, 4:06 a.m.)
Deposited 5 months, 4 weeks ago (Feb. 28, 2025, 1:22 p.m.)
Indexed 3 months, 1 week ago (May 18, 2025, 12:03 p.m.)
Issued 29 years, 3 months ago (May 1, 1996)
Published 29 years, 3 months ago (May 1, 1996)
Published Online 29 years, 3 months ago (May 1, 1996)
Published Print 29 years, 3 months ago (May 1, 1996)
Funders 0

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@article{Bredesen_1996, title={REVIEW ■ : Keeping Neurons Alive: The Molecular Control of Apoptosis (Part I}, volume={2}, ISSN={1089-4098}, url={http://dx.doi.org/10.1177/107385849600200313}, DOI={10.1177/107385849600200313}, number={3}, journal={The Neuroscientist}, publisher={SAGE Publications}, author={Bredesen, Dale E.}, year={1996}, month=may, pages={181–190} }