DOI: 10.1172/jci915. Genetic predisposition to the metabolism of irinotecan (CPT-11). Role of uridine diphosphate glucuronosyltransferase isoform 1A1 in the glucuronidation of its active metabolite (SN-38) in human liver microsomes.

Genetic predisposition to the metabolism of irinotecan (CPT-11). Role of uridine diphosphate glucuronosyltransferase isoform 1A1 in the glucuronidation of its active metabolite (SN-38) in human liver microsomes.

10.1172/jci915

Crossref journal-article

American Society for Clinical Investigation

Journal of Clinical Investigation (232)

Bibliography

Iyer, L., King, C. D., Whitington, P. F., Green, M. D., Roy, S. K., Tephly, T. R., Coffman, B. L., & Ratain, M. J. (1998). Genetic predisposition to the metabolism of irinotecan (CPT-11). Role of uridine diphosphate glucuronosyltransferase isoform 1A1 in the glucuronidation of its active metabolite (SN-38) in human liver microsomes. Journal of Clinical Investigation, 101(4), 847â854.

Authors 8

L Iyer (first)
C D King (additional)
P F Whitington (additional)
M D Green (additional)
S K Roy (additional)
T R Tephly (additional)
B L Coffman (additional)
M J Ratain (additional)

References 0 Referenced 541

None

Dates

Type	When
Created	17 years, 6 months ago (Feb. 11, 2008, 9:57 a.m.)
Deposited	2 years, 1 month ago (Aug. 3, 2023, 1:35 p.m.)
Indexed	2 weeks, 2 days ago (Aug. 21, 2025, 1:58 p.m.)
Issued	27 years, 6 months ago (Feb. 15, 1998)
Published	27 years, 6 months ago (Feb. 15, 1998)
Published Print	27 years, 6 months ago (Feb. 15, 1998)

Funders 0

None

BibTeX

@article{Iyer_1998, title={Genetic predisposition to the metabolism of irinotecan (CPT-11). Role of uridine diphosphate glucuronosyltransferase isoform 1A1 in the glucuronidation of its active metabolite (SN-38) in human liver microsomes.}, volume={101}, ISSN={0021-9738}, url={http://dx.doi.org/10.1172/jci915}, DOI={10.1172/jci915}, number={4}, journal={Journal of Clinical Investigation}, publisher={American Society for Clinical Investigation}, author={Iyer, L and King, C D and Whitington, P F and Green, M D and Roy, S K and Tephly, T R and Coffman, B L and Ratain, M J}, year={1998}, month=feb, pages={847–854} }

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