DOI: 10.1161/01.str.19.1.10. Failure of heparin to prevent progression in progressing ischemic infarction.

Failure of heparin to prevent progression in progressing ischemic infarction.

10.1161/01.str.19.1.10

Crossref journal-article

Ovid Technologies (Wolters Kluwer Health)

Stroke (276)

Abstract

Anticoagulation with heparin is frequently recommended for patients with progressing ischemic cerebral infarction, yet little data is available detailing the acute results of treatment with this agent. We report the results of continuous intravenous heparin treatment in 36 consecutive patients admitted with progressing ischemic infarction, all of whom had computed tomography scans to exclude the diagnosis of hemorrhage prior to treatment. Overall, 18 of 36 (50%) had continued neurologic worsening despite treatment. The incidence of further worsening was greater in carotid territory infarctions (14 of 19, 74%) than in either vertebrobasilar (2 of 8, 25%) or lacunar (2 of 9, 22%) infarctions (p less than 0.05, Fisher's exact test). These observations suggest that additional controlled studies of the efficacy of heparin in progressing ischemic infarction are warranted.

Bibliography

Haley, E. C., Kassell, N. F., & Torner, J. C. (1988). Failure of heparin to prevent progression in progressing ischemic infarction. Stroke, 19(1), 10â14.

Authors 3

E C Haley (first)
N F Kassell (additional)
J C Torner (additional)

References 0 Referenced 60

None

Dates

Type	When
Created	14 years, 2 months ago (June 17, 2011, 4:08 p.m.)
Deposited	1 year, 3 months ago (May 12, 2024, 5:45 p.m.)
Indexed	11 months, 1 week ago (Sept. 11, 2024, 10:35 p.m.)
Issued	37 years, 7 months ago (Jan. 1, 1988)
Published	37 years, 7 months ago (Jan. 1, 1988)
Published Print	37 years, 7 months ago (Jan. 1, 1988)

Funders 0

None

BibTeX

@article{Haley_1988, title={Failure of heparin to prevent progression in progressing ischemic infarction.}, volume={19}, ISSN={1524-4628}, url={http://dx.doi.org/10.1161/01.str.19.1.10}, DOI={10.1161/01.str.19.1.10}, number={1}, journal={Stroke}, publisher={Ovid Technologies (Wolters Kluwer Health)}, author={Haley, E C and Kassell, N F and Torner, J C}, year={1988}, month=jan, pages={10–14} }

JSON

{
  "indexed": {
    "date-parts": [
      [
        2024,
        9,
        12
      ]
    ],
    "date-time": "2024-09-12T02:35:29Z",
    "timestamp": 1726108529956
  },
  "reference-count": 0,
  "publisher": "Ovid Technologies (Wolters Kluwer Health)",
  "issue": "1",
  "content-domain": {
    "domain": [
      "www.ahajournals.org"
    ],
    "crossmark-restriction": true
  },
  "published-print": {
    "date-parts": [
      [
        1988,
        1
      ]
    ]
  },
  "abstract": "<jats:p>Anticoagulation with heparin is frequently recommended for patients with progressing ischemic cerebral infarction, yet little data is available detailing the acute results of treatment with this agent. We report the results of continuous intravenous heparin treatment in 36 consecutive patients admitted with progressing ischemic infarction, all of whom had computed tomography scans to exclude the diagnosis of hemorrhage prior to treatment. Overall, 18 of 36 (50%) had continued neurologic worsening despite treatment. The incidence of further worsening was greater in carotid territory infarctions (14 of 19, 74%) than in either vertebrobasilar (2 of 8, 25%) or lacunar (2 of 9, 22%) infarctions (p less than 0.05, Fisher's exact test). These observations suggest that additional controlled studies of the efficacy of heparin in progressing ischemic infarction are warranted.</jats:p>",
  "DOI": "10.1161/01.str.19.1.10",
  "type": "journal-article",
  "created": {
    "date-parts": [
      [
        2011,
        6,
        17
      ]
    ],
    "date-time": "2011-06-17T20:08:03Z",
    "timestamp": 1308341283000
  },
  "page": "10-14",
  "update-policy": "http://dx.doi.org/10.1161/crossmarkpolicy",
  "source": "Crossref",
  "is-referenced-by-count": 60,
  "title": "Failure of heparin to prevent progression in progressing ischemic infarction.",
  "prefix": "10.1161",
  "volume": "19",
  "author": [
    {
      "suffix": "Jr",
      "given": "E C",
      "family": "Haley",
      "sequence": "first",
      "affiliation": [
        {
          "name": "Department of Neurology, University of Virginia Medical Center, Charlottesville 22908."
        }
      ]
    },
    {
      "given": "N F",
      "family": "Kassell",
      "sequence": "additional",
      "affiliation": [
        {
          "name": "Department of Neurology, University of Virginia Medical Center, Charlottesville 22908."
        }
      ]
    },
    {
      "given": "J C",
      "family": "Torner",
      "sequence": "additional",
      "affiliation": [
        {
          "name": "Department of Neurology, University of Virginia Medical Center, Charlottesville 22908."
        }
      ]
    }
  ],
  "member": "276",
  "container-title": "Stroke",
  "original-title": [],
  "language": "en",
  "link": [
    {
      "URL": "https://www.ahajournals.org/doi/pdf/10.1161/01.STR.19.1.10",
      "content-type": "unspecified",
      "content-version": "vor",
      "intended-application": "similarity-checking"
    }
  ],
  "deposited": {
    "date-parts": [
      [
        2024,
        5,
        12
      ]
    ],
    "date-time": "2024-05-12T21:45:00Z",
    "timestamp": 1715550300000
  },
  "score": 1,
  "resource": {
    "primary": {
      "URL": "https://www.ahajournals.org/doi/10.1161/01.STR.19.1.10"
    }
  },
  "subtitle": [],
  "short-title": [],
  "issued": {
    "date-parts": [
      [
        1988,
        1
      ]
    ]
  },
  "references-count": 0,
  "journal-issue": {
    "issue": "1",
    "published-print": {
      "date-parts": [
        [
          1988,
          1
        ]
      ]
    }
  },
  "alternative-id": [
    "10.1161/01.STR.19.1.10"
  ],
  "URL": "http://dx.doi.org/10.1161/01.STR.19.1.10",
  "relation": {},
  "ISSN": [
    "0039-2499",
    "1524-4628"
  ],
  "subject": [],
  "container-title-short": "Stroke",
  "published": {
    "date-parts": [
      [
        1988,
        1
      ]
    ]
  },
  "assertion": [
    {
      "value": "1988-01-01",
      "order": 2,
      "name": "published",
      "label": "Published",
      "group": {
        "name": "publication_history",
        "label": "Publication History"
      }
    }
  ]
}