Abstract
Abstract Programmed cell death (apoptosis) is recognized, increasingly, as a contributing cause of cardiac myocyte loss with ischemia/reperfusion injury, myocardial infarction, and long-standing heart failure. Although the exact mechanisms initiating apoptosis in these in vivo settings remain unproven, insights into the molecular circuitry controlling apoptosis more widely suggest the potential to protect mammalian ventricular muscle from apoptosis through one or more of these pathways, by pharmacological means or, conceivably, gene transfer.
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Dates
Type | When |
---|---|
Created | 13 years, 2 months ago (June 11, 2012, 8:47 p.m.) |
Deposited | 1 year, 3 months ago (May 12, 2024, 4:44 p.m.) |
Indexed | 1 month, 2 weeks ago (July 14, 2025, 11:47 p.m.) |
Issued | 28 years ago (Aug. 1, 1997) |
Published | 28 years ago (Aug. 1, 1997) |
Published Print | 28 years ago (Aug. 1, 1997) |
@article{MacLellan_1997, title={Death by Design: Programmed Cell Death in Cardiovascular Biology and Disease}, volume={81}, ISSN={1524-4571}, url={http://dx.doi.org/10.1161/01.res.81.2.137}, DOI={10.1161/01.res.81.2.137}, number={2}, journal={Circulation Research}, publisher={Ovid Technologies (Wolters Kluwer Health)}, author={MacLellan, W. Robb and Schneider, Michael D.}, year={1997}, month=aug, pages={137–144} }