DOI: 10.1159/000234328. Effects of Some Prostaglandins and Leukotrienes on Lymphocytes, Monocytes and Their Activity in vitro

Effects of Some Prostaglandins and Leukotrienes on Lymphocytes, Monocytes and Their Activity in vitro

10.1159/000234328

Crossref journal-article

S. Karger AG

International Archives of Allergy and Immunology (127)

Abstract

The effect of some prostaglandins (PGs) and leukotrienes (LTs) on lymphocytes and monocytes was tested in vitro. Overnight incubation with PGD2 reduces the expression of Leu-2 antigen (suppressor/cytotoxic phenotype) and of Fc receptors for IgG. PGA2, PGD2 and to a lesser extent PGE2 inhibit PHA reactivity of lymphocytes. LTB4 does not have any inhibitory activity. Preincubation of lymphocytes with PGD2 and PGE2 decreases their NK activity. LTB4, but not the PGs tested, stimulates monocyte metabolism as assessed by chemiluminescence.

Bibliography

Wasserman, J., HammarstrÃ¶m, S., Petrini, B., Blomgren, H., von Stedingk, L.-V., & Vedin, I. (1987). Effects of Some Prostaglandins and Leukotrienes on Lymphocytes, Monocytes and Their Activity in vitro. International Archives of Allergy and Immunology, 83(1), 39â43. Portico.

Authors 6

J. Wasserman (first)
S. Hammarström (additional)
B. Petrini (additional)
H. Blomgren (additional)
L.-V. von Stedingk (additional)
I. Vedin (additional)

References 0 Referenced 12

None

Dates

Type	When
Created	16 years ago (Aug. 7, 2009, 9:46 a.m.)
Deposited	4 months, 1 week ago (April 23, 2025, 5:53 p.m.)
Indexed	4 months, 1 week ago (April 24, 2025, 12:44 a.m.)
Issued	38 years, 8 months ago (Jan. 1, 1987)
Published	38 years, 8 months ago (Jan. 1, 1987)
Published Online	16 years ago (Aug. 5, 2009)
Published Print	38 years, 8 months ago (Jan. 1, 1987)

Funders 0

None

BibTeX

@article{Wasserman_1987, title={Effects of Some Prostaglandins and Leukotrienes on Lymphocytes, Monocytes and Their Activity in vitro}, volume={83}, ISSN={1423-0097}, url={http://dx.doi.org/10.1159/000234328}, DOI={10.1159/000234328}, number={1}, journal={International Archives of Allergy and Immunology}, publisher={S. Karger AG}, author={Wasserman, J. and Hammarström, S. and Petrini, B. and Blomgren, H. and von Stedingk, L.-V. and Vedin, I.}, year={1987}, pages={39–43} }

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