DOI: 10.1159/000133603. Structure, expression and chromosome assignment of the human catenin (cadherin-associated protein) alpha 1 gene (CTNNA1)

Structure, expression and chromosome assignment of the human catenin (cadherin-associated protein) alpha 1 gene (CTNNA1)

10.1159/000133603

Crossref journal-article

S. Karger AG

Cytogenetic and Genome Research (127)

Abstract

We have isolated the human α-catenin gene (CTNNAl), which encodes a cadherin-associated protein, and have determined its primary structure and chromosomal localization. The transcript of CTNNAl is 3.4 kb long and consists of 16 coding exons encoding 906 amino acids and at least one 5’ noncoding exon. The 102-kDa predicted protein is the same size as the murine homolog, and the amino acid sequences of the two proteins are 99.2% homologous. Analysis by reverse transcription-PCR revealed that this gene is expressed ubiquitously in normal tissues. It was mapped to chromosome band 5q31 by fluorescent in situ hybridization.

Bibliography

Furukawa, Y., Nakatsuru, S., Nagafuchi, A., Tsukita, S., Muto, T., Nakamura, Y., & Horii, A. (1994). Structure, expression and chromosome assignment of the human catenin (cadherin-associated protein) alpha 1 gene (CTNNA1). Cytogenetic and Genome Research, 65(1â2), 74â78. Portico.

Authors 7

Y. Furukawa (first)
S. Nakatsuru (additional)
A. Nagafuchi (additional)
S. Tsukita (additional)
T. Muto (additional)
Y. Nakamura (additional)
A. Horii (additional)

References 0 Referenced 28

None

Dates

Type	When
Created	17 years, 3 months ago (May 16, 2008, 8:10 a.m.)
Deposited	4 months, 2 weeks ago (April 23, 2025, 9:34 p.m.)
Indexed	4 days, 6 hours ago (Sept. 3, 2025, 6:36 a.m.)
Issued	31 years, 8 months ago (Jan. 1, 1994)
Published	31 years, 8 months ago (Jan. 1, 1994)
Published Online	17 years, 3 months ago (May 14, 2008)
Published Print	31 years, 8 months ago (Jan. 1, 1994)

Funders 0

None

BibTeX

@article{Furukawa_1994, title={Structure, expression and chromosome assignment of the human catenin (cadherin-associated protein) alpha 1 gene (CTNNA1)}, volume={65}, ISSN={1424-859X}, url={http://dx.doi.org/10.1159/000133603}, DOI={10.1159/000133603}, number={1–2}, journal={Cytogenetic and Genome Research}, publisher={S. Karger AG}, author={Furukawa, Y. and Nakatsuru, S. and Nagafuchi, A. and Tsukita, S. and Muto, T. and Nakamura, Y. and Horii, A.}, year={1994}, pages={74–78} }

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