DOI: 10.1159/000053973. Human Cytomegalovirus Infection of Immature Dendritic Cells and Macrophages

Human Cytomegalovirus Infection of Immature Dendritic Cells and Macrophages

10.1159/000053973

Crossref journal-article

S. Karger AG

Intervirology (127)

Abstract

A central aspect of human cytomegalovirus (HCMV) pathogenesis is the interaction of the virus with different antigen-presenting cell (APC) types of the host. In principle, a number of various cell types have the potential of antigen presentation when MHC II expression is induced by appropriate stimuli. The most potent antigen presenters are monocytes/macrophages and dendritic cells (DCs), therefore called professional APCs. Interestingly, these cells seem to be targets of productive HCMV infection. The susceptibility of the monocyte/macrophage system has been analyzed intensively during the past decade. Investigation of the role of DCs during HCMV infection, however, has begun only recently.

Bibliography

Jahn, G., Stenglein, S., Riegler, S., Einsele, H., & Sinzger, C. (1999). Human Cytomegalovirus Infection of Immature Dendritic Cells and Macrophages. Intervirology, 42(5â6), 365â372. Portico.

Authors 5

Gerhard Jahn (first)
Stephan Stenglein (additional)
Susanne Riegler (additional)
Hermann Einsele (additional)
Christian Sinzger (additional)

References 5 Referenced 35

Dates

Type	When
Created	22 years, 4 months ago (April 15, 2003, 1:26 p.m.)
Deposited	4 months, 1 week ago (April 24, 2025, 12:30 a.m.)
Indexed	4 months, 1 week ago (April 25, 2025, 12:13 a.m.)
Issued	26 years, 8 months ago (Jan. 1, 1999)
Published	26 years, 8 months ago (Jan. 1, 1999)
Published Online	25 years, 6 months ago (Feb. 28, 2000)
Published Print	26 years, 8 months ago (Jan. 1, 1999)

Funders 0

None

BibTeX

@article{Jahn_1999, title={Human Cytomegalovirus Infection of Immature Dendritic Cells and Macrophages}, volume={42}, ISSN={1423-0100}, url={http://dx.doi.org/10.1159/000053973}, DOI={10.1159/000053973}, number={5–6}, journal={Intervirology}, publisher={S. Karger AG}, author={Jahn, Gerhard and Stenglein, Stephan and Riegler, Susanne and Einsele, Hermann and Sinzger, Christian}, year={1999}, pages={365–372} }

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