Crossref journal-article
American Physiological Society
Physiological Reviews (24)
Abstract

Secretion of neurotransmitter is the primary means of intercellular communication within the nervous system. This process is regulated by a highly orchestrated cycle of membrane trafficking within the presynaptic nerve terminal. Characterization of proteins localized to the synaptic vesicle and the subsequent studies of their properties have led to a model for the biochemical pathway that underlies vesicle docking, activation, and fusion. The proteins found to function in the synapse are related to those in yeast and other organisms, demonstrating that the mechanisms that mediate vesicle trafficking are conserved in all eukaryotic species.

Bibliography

Calakos, N., & Scheller, R. H. (1996). Synaptic vesicle biogenesis, docking, and fusion: a molecular description. Physiological Reviews, 76(1), 1–29.

Authors 2
  1. N. Calakos (first)
  2. R. H. Scheller (additional)
References 0 Referenced 279

None

Dates
Type When
Created 7 years, 8 months ago (Dec. 24, 2017, 1:08 p.m.)
Deposited 5 years, 11 months ago (Sept. 8, 2019, 7:09 p.m.)
Indexed 1 month, 3 weeks ago (July 7, 2025, 2:29 a.m.)
Issued 29 years, 8 months ago (Jan. 1, 1996)
Published 29 years, 8 months ago (Jan. 1, 1996)
Published Print 29 years, 8 months ago (Jan. 1, 1996)
Funders 0

None

@article{Calakos_1996, title={Synaptic vesicle biogenesis, docking, and fusion: a molecular description}, volume={76}, ISSN={1522-1210}, url={http://dx.doi.org/10.1152/physrev.1996.76.1.1}, DOI={10.1152/physrev.1996.76.1.1}, number={1}, journal={Physiological Reviews}, publisher={American Physiological Society}, author={Calakos, N. and Scheller, R. H.}, year={1996}, month=jan, pages={1–29} }