ZINC AND THE RISK FOR INFECTIOUS DISEASE
10.1146/annurev.nutr.23.011702.073054
Crossref journal-article
Annual Reviews
Annual Review of Nutrition (22)
Abstract

▪ Abstract  Zinc is an essential micronutrient for human growth, development, and immune function. Zinc deficiency impairs overall immune function and resistance to infection. Mild to moderate zinc deficiency can be best detected through a positive response to supplementation trials. Zinc supplementation has been shown to have a positive effect on the incidence of diarrhea (18% reduction, 95% CI: 7–28%) and pneumonia (41% reduction, 95% CI: 17–59%), and might lead to a decrease in the incidence of malaria. Zinc has also proven to decrease the duration of diarrhea by 15% (95% CI: 5–24%). Maternal zinc supplementation may lead to a decrease in infant infections. Studies assessing the role of zinc supplementation among persons with HIV, tuberculosis, and the common cold have not been conclusive. Two studies have shown zinc supplementation to decrease child mortality by more than 50%. Zinc clearly has an important role in infant and childhood infectious diseases; programs to increase the intake of zinc among deficient populations are needed.

Bibliography

Walker, C. F., & Black, R. E. (2004). ZINC AND THE RISK FOR INFECTIOUS DISEASE. Annual Review of Nutrition, 24(1), 255–275.

Authors 2
  1. Christa Fischer Walker (first)
  2. Robert E. Black (additional)
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Dates
Type When
Created 21 years, 2 months ago (June 9, 2004, 3:06 p.m.)
Deposited 3 years, 10 months ago (Oct. 15, 2021, 5:57 p.m.)
Indexed 1 month ago (July 30, 2025, 8:23 p.m.)
Issued 21 years, 1 month ago (July 14, 2004)
Published 21 years, 1 month ago (July 14, 2004)
Published Print 21 years, 1 month ago (July 14, 2004)
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