DOI: 10.1146/annurev.med.45.1.459. STRATEGIES FOR ATTENUATING PROTEIN-CATABOLIC RESPONSES IN THE CRITICALLY ILL

STRATEGIES FOR ATTENUATING PROTEIN-CATABOLIC RESPONSES IN THE CRITICALLY ILL

10.1146/annurev.med.45.1.459

Crossref journal-article

Annual Reviews

Annual Review of Medicine (22)

Abstract

▪ Abstract Specialized enteral and parenteral nutrition are now a standard components of care in critically ill patients. This adjunctive therapy corrects and prevents nutrient deficiencies, attenuates the loss of body protein, and improves clinical outcomes in malnourished patients. Several novel strategies designed to improve the metabolic and clinical effects of specialized nutrition are under vigorous clinical investigation. These new approaches include increased emphasis on enteral feeding to maintain intestinal absorptive, immune, and barrier function; administration of conditionally essential amino acids (glutamine, arginine); use of specialized lipid products and antiox idants; and administration of growth factors such as human growth hormone. Randomized, controlled clinical trials will define the clinical and metabolic efficacy and cost-effectiveness of these therapies in specialized nutrition support.

Bibliography

Ziegler, M.D, T. R., Gatzen, FRCS, C., & Wilmore, M.D, D. W. (1994). STRATEGIES FOR ATTENUATING PROTEIN-CATABOLIC RESPONSES IN THE CRITICALLY ILL. Annual Review of Medicine, 45(1), 459â480.

Authors 3

Thomas R. Ziegler, M.D (first)
Christopher Gatzen, FRCS (additional)
Douglas W. Wilmore, M.D (additional)

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Dates

Type	When
Created	23 years, 1 month ago (July 27, 2002, 7:45 a.m.)
Deposited	3 years, 10 months ago (Oct. 13, 2021, 9:59 p.m.)
Indexed	1 year, 1 month ago (July 7, 2024, 12:38 p.m.)
Issued	31 years, 6 months ago (Feb. 1, 1994)
Published	31 years, 6 months ago (Feb. 1, 1994)
Published Print	31 years, 6 months ago (Feb. 1, 1994)

Funders 0

None

BibTeX

@article{Ziegler_M_D_1994, M.D_Gatzen, FRCS_Wilmore, M.D_1994, title={STRATEGIES FOR ATTENUATING PROTEIN-CATABOLIC RESPONSES IN THE CRITICALLY ILL}, volume={45}, ISSN={1545-326X}, url={http://dx.doi.org/10.1146/annurev.med.45.1.459}, DOI={10.1146/annurev.med.45.1.459}, number={1}, journal={Annual Review of Medicine}, publisher={Annual Reviews}, author={Ziegler, M.D, Thomas R. and Gatzen, FRCS, Christopher and Wilmore, M.D, Douglas W.}, year={1994}, month=feb, pages={459–480} }

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