Abstract
▪ Abstract Saccharomyces cerevisiae can change its mating type as often as every generation by a highly choreographed, site-specific recombination event that replaces one MAT allele with different DNA sequences encoding the opposite allele. The study of this process has yielded important insights into the control of cell lineage, the silencing of gene expression, and the formation of heterochromatin, as well as the molecular events of double-strand break-induced recombination. In addition, MAT switching provides a remarkable example of a small locus control region—the Recombination Enhancer—that controls recombination along an entire chromosome arm.
References
227
Referenced
309
10.1016/0022-2836(84)90492-3
10.1126/science.270.5237.815
10.1074/jbc.272.6.3823
10.1128/MCB.17.12.7061
10.1016/S0092-8674(01)80009-X
10.1093/emboj/17.15.4503
10.1016/0092-8674(81)90356-1
10.1128/MCB.11.2.1080
10.1146/annurev.ge.28.120194.002423
10.1038/34937
10.1128/MCB.17.12.7077
10.1126/science.272.5265.1190a
10.1016/S0092-8674(00)81048-X
10.1101/gad.9.23.2888
10.1016/0092-8674(85)90059-5
10.1128/MCB.16.8.4349
10.1128/MCB.14.4.2534
10.1016/S0955-0674(96)80035-4
10.1016/S0021-9258(18)54049-7
/ J. Biol. Chem. by Chen-Cleland TA (1993)10.1128/MCB.16.8.4281
10.1016/0092-8674(93)90387-6
10.1016/0092-8674(94)90255-0
10.1126/science.274.5293.1736
10.1083/jcb.132.3.259
10.1093/emboj/16.9.2535
10.1128/MCB.14.5.3524
10.1128/MCB.8.6.2342
10.1038/384589a0
10.1002/(SICI)1097-0061(19960615)12:7<631::AID-YEA960>3.3.CO;2-#
10.1128/MCB.11.10.5346
10.1126/science.270.5242.1671
10.1093/genetics/145.4.923
/ Genetics by Ehrenhofer-Murray AE (1997)10.1073/pnas.88.23.10966
10.1101/gad.12.2.219
10.1016/0022-2836(84)90313-9
10.1073/pnas.93.11.5419
10.1002/j.1460-2075.1995.tb07133.x
10.1126/science.1411547
10.1101/gad.4.10.1637
10.1126/science.8266071
10.1126/science.276.5318.1547
10.1074/jbc.271.40.24337
10.1093/genetics/59.1.33
/ Genetics by Friis J (1968)10.1093/emboj/16.21.6495
10.1002/j.1460-2075.1990.tb07884.x
10.1016/0092-8674(89)90681-8
10.1016/0092-8674(90)90141-Z
10.1016/0092-8674(88)90429-1
10.1016/S0955-0674(97)80011-7
10.1016/S0092-8674(00)81160-5
10.1002/bies.950170707
10.1016/0168-9525(92)90178-7
10.1093/genetics/93.1.13
/ Genetics by Haber JE (1979)10.1016/0092-8674(80)90638-8
10.1073/pnas.90.8.3363
10.1128/MCB.1.12.1106
10.1128/MCB.13.11.6866
10.1093/genetics/48.12.1727
/ Genetics by Hawthorne DC (1963){'key': 'b59', 'first-page': '34', 'volume': '1', 'author': 'Hawthorne DC', 'year': '1963', 'journal-title': 'Proc. Int. Congr. Genet.'}
/ Proc. Int. Congr. Genet. by Hawthorne DC (1963)10.1073/pnas.92.15.6925
10.1016/0092-8674(95)90512-X
10.1038/383092a0
10.1038/370309a0
10.1128/mr.52.4.536-553.1988
/ Microbiol. Rev. by Herskowitz I (1988)10.1093/genetics/133.3.489
/ Genetics by Heude M (1993)10.1128/MCB.4.7.1278
10.1038/282478a0
10.1093/genetics/85.3.373
/ Genetics by Hicks JB (1977)- Hicks JB, Strathern JN, Herskowitz I. 1977. The cassette model of mating-type interconversion. InDNA Insertion Elements, Plasmids and Episomes, ed. AI Bukhari, JA Shapiro, SL Adhya, pp. 457–62. Cold Spring Harbor, NY: Cold Spring Harbor Lab.
10.1101/gad.10.8.1021
10.1093/genetics/145.3.605
/ Genetics by Holmes SG (1997)10.1128/MCB.17.11.6693
10.1128/MCB.15.4.2245
10.1093/genetics/142.3.693
/ Genetics by Ivanov EL (1996)10.1128/MCB.14.5.3414
10.1016/S0092-8674(00)81047-8
10.1101/SQB.1984.049.01.013
10.1073/pnas.80.10.3035
10.1074/jbc.272.11.7352
10.1073/pnas.87.16.6286
10.1128/MCB.9.11.5228
10.1016/0092-8674(95)90499-9
10.1016/S0092-8674(00)80219-6
10.1002/j.1460-2075.1988.tb03064.x
10.1016/0092-8674(87)90442-9
10.1016/S0959-437X(05)80093-0
10.1073/pnas.76.9.4539
10.1016/0092-8674(82)90210-0
10.1093/genetics/111.4.745
/ Genetics by Klar AJ (1985)10.1038/310744a0
10.1016/0092-8674(81)90070-2
10.1093/genetics/93.1.37
/ Genetics by Klar AJS (1979)10.1073/pnas.93.16.8167
10.1016/0092-8674(83)90219-2
10.1093/genetics/129.3.685
/ Genetics by Laurenson P (1991)10.1128/mr.56.4.543-560.1992
/ Microbiol. Rev. by Laurenson P (1992)- Deleted in proof
- Deleted in proof
10.1073/pnas.94.13.6851
10.1126/science.270.5234.262
10.1093/genetics/88.4.651
/ Genetics by Liras P (1978)10.1126/science.277.5324.383
10.1093/genetics/141.3.889
/ Genetics by Loo S (1995)10.1126/science.8209257
10.1016/S0959-437X(98)80146-9
10.1101/gad.8.18.2212
10.1128/MCB.9.11.4621
10.1101/gad.10.14.1796
10.1073/pnas.93.14.7131
10.1101/gad.10.11.1297
10.1016/S0960-9822(06)00412-X
10.1016/0092-8674(89)90921-5
10.1007/BF00310891
10.1128/MCB.17.8.4553
10.1128/MCB.11.11.5648
10.1038/312247a0
10.1101/gad.7.9.1755
10.1016/S0092-8674(00)80139-7
10.1073/pnas.94.6.2186
10.1073/pnas.93.20.10729
10.1002/j.1460-2075.1989.tb03615.x
10.1146/annurev.ge.16.120182.002255
10.1038/302670a0
10.1002/j.1460-2075.1987.tb04745.x
10.1126/science.3306917
10.1016/0092-8674(82)90253-7
10.1016/S0092-8674(80)80051-1
10.1128/MCB.14.3.1613
{'key': 'b129', 'first-page': '82', 'volume': '9', 'author': 'Naumov GI', 'year': '1973', 'journal-title': 'Genetika'}
/ Genetika by Naumov GI (1973)10.1038/34950
10.1073/pnas.83.20.7831
10.1016/0022-2836(89)90462-2
10.1126/science.8456314
10.1093/genetics/67.3.327
/ Genetics by Oshima Y (1971)10.1016/0092-8674(93)90388-7
10.1128/MCB.18.4.2045
10.1128/MCB.10.9.4932
10.1093/genetics/140.1.67
/ Genetics by Parket A (1995)10.1126/science.8178152
10.1128/MCB.14.6.4002
10.1038/379131a0
- Petes TD, Malone RE, Symington LS. 1991. Recombination in Yeast. InThe Molecular and Cellular Biology of the Yeast Saccharomyces. ed. EW Jones, JR Pringle, pp. 407–521. Cold Spring Harbor, NY: Cold Spring Harbor Lab.
10.1016/0092-8674(89)90009-3
10.1093/genetics/130.3.451
/ Genetics by Plessis A (1992)10.1093/genetics/134.1.5
/ Genetics by Porter SE (1993)10.1016/0925-4773(95)00438-7
10.1093/genetics/138.3.587
/ Genetics by Rattray AJ (1994)10.1093/genetics/139.1.45
/ Genetics by Rattray AJ (1995)10.1007/BF00260852
10.1073/pnas.86.16.6225
10.1128/MCB.11.10.5372
10.1038/ng0996-42
10.1007/BF00267357
10.1093/genetics/116.1.9
/ Genetics by Rine J (1987)10.1093/genetics/93.4.877
/ Genetics by Rine J (1979)10.1126/science.1585179
10.1111/j.1365-2958.1992.tb01485.x
10.1128/MCB.8.9.3918
10.1093/genetics/122.3.519
/ Genetics by Rudin N (1989)10.1073/pnas.93.25.14503
10.1016/0092-8674(93)90493-A
{'key': 'b162', 'first-page': '1', 'volume': '30', 'author': 'Santa Maria J', 'year': '1970', 'journal-title': 'Inst. Nac. Invest. Agron. Conf.'}
/ Inst. Nac. Invest. Agron. Conf. by Santa Maria J (1970)10.1128/MCB.6.2.494
10.1111/j.1365-2958.1995.mmi_17061215_1.x
10.1128/MCB.15.7.3496
10.1016/S0168-9525(97)01198-0
10.1016/0092-8674(92)90447-K
10.1038/34943
10.1016/S0092-8674(00)81049-1
10.1126/science.277.5330.1313
10.1016/S0092-8674(00)81038-7
10.1002/j.1460-2075.1994.tb06521.x
10.1101/gad.11.2.241
10.1093/genetics/149.3.1205
/ Genetics by Smith JS (1998)10.1038/289250a0
10.1083/jcb.135.3.571
10.1002/(SICI)1521-1878(199801)20:1<30::AID-BIES6>3.0.CO;2-W
10.1101/gad.11.1.83
10.1126/science.277.5325.574
10.1016/0022-2836(81)90488-5
10.1093/genetics/120.1.75
/ Genetics by Strathern J (1988)- Strathern JN. 1989. Control and execution of mating type switching inSaccharomyces cerevisiae. InGenetic Recombination, ed. R Kucherlapati, GR Smith, pp. 445–64. Washington, DC: Am. Soc. Microbiol.
10.1016/0092-8674(79)90163-6
10.1016/0092-8674(82)90418-4
10.1016/0092-8674(79)90050-3
10.1073/pnas.77.5.2839
10.1128/MCB.12.2.563
10.1038/373084a0
10.1073/pnas.94.17.9214
10.1074/jbc.272.45.28194
10.1101/gad.11.9.1111
10.1016/0092-8674(95)90434-4
10.1128/MCB.17.2.751
10.1101/gad.11.15.1899
10.1016/0092-8674(83)90331-8
10.1093/genetics/43.4.705
/ Genetics by Takahashi T (1958)10.1093/genetics/57.4.875
/ Genetics by Takano I (1967)10.1038/38015
10.1038/35563
10.1128/MCB.4.1.203
10.1016/0092-8674(81)90357-3
10.1128/MCB.14.1.446
10.1038/369245a0
10.1093/genetics/138.1.29
/ Genetics by Thon G (1994)10.1093/genetics/145.3.685
/ Genetics by Thon G (1997)10.1093/genetics/131.2.287
/ Genetics by Thon G (1992)10.1093/genetics/134.4.1045
/ Genetics by Thon G (1993)10.1128/MCB.18.1.260
10.1093/nar/24.11.2067
10.1038/42288
10.1093/genetics/148.3.989
/ Genetics by Umezu K (1998)10.1128/MCB.17.2.770
10.1128/MCB.1.6.522
10.1093/genetics/132.4.929
/ Genetics by Weiler KS (1992)10.1093/genetics/139.4.1495
/ Genetics by Weiler KS (1995)10.1128/MCB.10.6.2882
10.1093/emboj/16.14.4352
{'key': 'b218', 'author': 'Weiss K', 'year': '1998', 'journal-title': 'Mol. Cell. Biol.'}
/ Mol. Cell. Biol. by Weiss K (1998)10.1007/s002940050054
10.1002/j.1460-2075.1990.tb08158.x
10.1128/MCB.7.10.3713
10.1101/gad.12.11.1726
10.1101/gad.9.15.1922
10.1016/S0092-8674(00)81345-8
10.1128/MCB.16.2.657
10.1093/genetics/147.2.399
/ Genetics by Wu X (1997)10.1128/MCB.17.9.5461
Dates
Type | When |
---|---|
Created | 23 years, 1 month ago (July 27, 2002, 7:43 a.m.) |
Deposited | 3 years, 10 months ago (Oct. 12, 2021, 8:22 a.m.) |
Indexed | 2 months ago (July 2, 2025, 3:07 p.m.) |
Issued | 26 years, 9 months ago (Dec. 1, 1998) |
Published | 26 years, 9 months ago (Dec. 1, 1998) |
Published Print | 26 years, 9 months ago (Dec. 1, 1998) |
@article{Haber_1998, title={MATING-TYPE GENE SWITCHING IN SACCHAROMYCES CEREVISIAE}, volume={32}, ISSN={1545-2948}, url={http://dx.doi.org/10.1146/annurev.genet.32.1.561}, DOI={10.1146/annurev.genet.32.1.561}, number={1}, journal={Annual Review of Genetics}, publisher={Annual Reviews}, author={Haber, James E.}, year={1998}, month=dec, pages={561–599} }