DOI: 10.1146/annurev.cellbio.13.1.83. MICROTUBULE POLYMERIZATION DYNAMICS

10.1146/annurev.cellbio.13.1.83

Crossref journal-article

Annual Reviews

Annual Review of Cell and Developmental Biology (22)

Abstract

▪ Abstract The polymerization dynamics of microtubules are central to their biological functions. Polymerization dynamics allow microtubules to adopt spatial arrangements that can change rapidly in response to cellular needs and, in some cases, to perform mechanical work. Microtubules utilize the energy of GTP hydrolysis to fuel a unique polymerization mechanism termed dynamic instability. In this review, we first describe progress toward understanding the mechanism of dynamic instability of pure tubulin and then discuss the function and regulation of microtubule dynamic instability in living cells.

Bibliography

Desai, A., & Mitchison, T. J. (1997). MICROTUBULE POLYMERIZATION DYNAMICS. Annual Review of Cell and Developmental Biology, 13(1), 83â117.

Authors 2

Arshad Desai (first)
Timothy J. Mitchison (additional)

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Dates

Type	When
Created	23 years ago (July 27, 2002, 7:49 a.m.)
Deposited	2 years, 3 months ago (April 23, 2023, 3:40 p.m.)
Indexed	2 days, 13 hours ago (Aug. 20, 2025, 8:21 a.m.)
Issued	27 years, 9 months ago (Nov. 1, 1997)
Published	27 years, 9 months ago (Nov. 1, 1997)
Published Print	27 years, 9 months ago (Nov. 1, 1997)

Funders 0

None

BibTeX

@article{Desai_1997, title={MICROTUBULE POLYMERIZATION DYNAMICS}, volume={13}, ISSN={1530-8995}, url={http://dx.doi.org/10.1146/annurev.cellbio.13.1.83}, DOI={10.1146/annurev.cellbio.13.1.83}, number={1}, journal={Annual Review of Cell and Developmental Biology}, publisher={Annual Reviews}, author={Desai, Arshad and Mitchison, Timothy J.}, year={1997}, month=nov, pages={83–117} }

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