STRUCTURE AND CONFORMATION OF COMPLEX CARBOHYDRATES OF GLYCOPROTEINS, GLYCOLIPIDS, AND BACTERIAL POLYSACCHARIDES
10.1146/annurev.biophys.28.1.269
Crossref journal-article
Annual Reviews
Annual Review of Biophysics and Biomolecular Structure (22)
Abstract

▪ Abstract  For nuclear magnetic resonance determinations of the conformation of oligosaccharides in solution, simple molecular mechanics calculations and nuclear Overhauser enhancement measurements are adequate for small oligosaccharides that adopt single, relatively rigid conformations. Polysaccharides and larger or more flexible oligosaccharides generally require additional types of data, such as scalar and dipolar coupling constants, which are most conveniently measured in 13C-enriched samples. Nuclear magnetic resonance relaxation data provide information on the dynamics of oligosaccharides, which involves several different types of internal motion. Oligosaccharides complexed with lectins and antibodies have been successfully studied both by X-ray crystallography and by nuclear magnetic resonance spectroscopy. The complexes have been shown to be stabilized by a combination of polar hydrogen bonding interactions and van der Waals attractions. Although theoretical calculations of the conformation and stability of free oligosaccharides and of complexes with proteins can be carried out by molecular mechanics methods, the role of solvent water for these highly polar molecules continues to present computational problems.

Bibliography

Bush, C. A., Martin-Pastor, M., & Imbery, A. (1999). STRUCTURE AND CONFORMATION OF COMPLEX CARBOHYDRATES OF GLYCOPROTEINS, GLYCOLIPIDS, AND BACTERIAL POLYSACCHARIDES. Annual Review of Biophysics and Biomolecular Structure, 28(1), 269–293.

Authors 3
  1. C. Allen Bush (first)
  2. Manuel Martin-Pastor (additional)
  3. Anne Imbery (additional)
References 150 Referenced 126
  1. {'key': 'b1', 'first-page': '199', 'volume': '3', 'author': 'Abeygunawardana C', 'year': '1993', 'journal-title': 'Adv. Biophys. Chem.'} / Adv. Biophys. Chem. by Abeygunawardana C (1993)
  2. 10.1021/ja00205a001
  3. 10.1021/ja00179a012
  4. 10.1006/jmrb.1995.1033
  5. 10.1021/bi00064a028
  6. 10.1021/ja962807q
  7. {'key': 'b7', 'first-page': '207', 'volume': '63', 'author': 'Bax A', 'year': '1985', 'journal-title': 'J. Magn. Reson.'} / J. Magn. Reson. by Bax A (1985)
  8. 10.1016/0009-2614(90)85352-D
  9. 10.1021/jm9606812
  10. 10.1016/S0022-2836(77)80200-3
  11. 10.1007/BF00198137
  12. 10.1021/ja981127f
  13. 10.1038/nsb1294-863
  14. 10.1016/S0969-2126(00)00022-8
  15. 10.1016/S0021-9258(18)48479-7 / J. Biol. Chem. by Bourne Y (1992)
  16. 10.1021/j100106a024
  17. 10.1016/0008-6215(95)00242-4
  18. 10.1111/j.1432-1033.1989.tb14504.x
  19. 10.1021/bi00275a007
  20. 10.1021/bi961819l
  21. 10.1021/bi00183a023
  22. 10.1016/0959-440X(92)90197-F
  23. 10.1016/S0076-6879(94)40059-8
  24. {'key': 'b24', 'first-page': '149', 'volume': '2', 'author': 'Bush CA', 'year': '1992', 'journal-title': 'Adv. Biophys. Chem.'} / Adv. Biophys. Chem. by Bush CA (1992)
  25. 10.1002/bip.360301112
  26. 10.1016/0959-440X(91)90170-X
  27. 10.1111/j.1432-1033.1996.0710u.x
  28. 10.1016/S0065-2318(08)60094-3
  29. 10.1016/0008-6215(95)00311-8
  30. {'key': 'b30', 'first-page': '423', 'volume': '53', 'author': 'Clore GM', 'year': '1983', 'journal-title': 'J. Magn. Reson.'} / J. Magn. Reson. by Clore GM (1983)
  31. 10.1021/ja00168a070
  32. 10.1021/bi00201a004
  33. 10.1021/bi00395a016
  34. 10.1126/science.1713710
  35. 10.1021/ja00186a063
  36. 10.1002/(SICI)1096-987X(199712)18:16<1955::AID-JCC1>3.3.CO;2-A
  37. 10.1021/ja00245a055
  38. 10.1080/00268979400100631
  39. 10.1021/ja00164a066
  40. 10.1016/S0969-2126(97)00202-5
  41. 10.1016/S0021-9258(18)60556-3 / J. Biol. Chem. by Eggens I (1989)
  42. 10.1006/viro.1997.8526
  43. 10.1021/j100036a005
  44. 10.1016/S0008-6215(96)91019-8
  45. 10.1021/ja9603463
  46. 10.1016/0959-440X(91)90176-T
  47. 10.1002/bip.360341005
  48. 10.1021/jm00145a002
  49. 10.1016/0008-6215(88)80078-8
  50. 10.1002/(SICI)1097-0282(199701)41:1<83::AID-BIP8>3.0.CO;2-Z
  51. 10.1023/A:1018671517876
  52. 10.1091/mbc.5.3.253
  53. 10.1016/0079-6565(90)80014-9
  54. 10.1021/bi00491a003
  55. 10.1093/glycob/2.2.153
  56. 10.1093/glycob/3.6.551
  57. 10.1016/0008-6215(95)00204-7
  58. 10.1002/(SICI)1097-0282(199805)45:6<435::AID-BIP3>3.0.CO;2-Q
  59. 10.1021/ja00034a083
  60. 10.1016/S0959-440X(97)80069-3
  61. {'key': 'b61', 'first-page': '71', 'volume': '3', 'author': 'Imberty A', 'year': '1993', 'journal-title': 'Adv. Biophys. Chem.'} / Adv. Biophys. Chem. by Imberty A (1993)
  62. 10.1093/glycob/1.6.631
  63. 10.1093/protein/8.7.699
  64. 10.1002/3527603239.ch18
  65. 10.1002/jcc.540110206
  66. {'key': 'b66', 'first-page': '149', 'volume': '4', 'author': 'Jarrell HC', 'year': '1994', 'journal-title': 'Adv. Biophys. Chem.'} / Adv. Biophys. Chem. by Jarrell HC (1994)
  67. 10.1007/978-3-642-85135-3
  68. 10.1038/nsb0695-466
  69. 10.1021/ja00196a017
  70. {'key': 'b70', 'volume-title': 'The Anomeric Effect and Related Stereoelectronic Effects at Oxygen.', 'author': 'Kirvy AJ', 'year': '1983'} / The Anomeric Effect and Related Stereoelectronic Effects at Oxygen. by Kirvy AJ (1983)
  71. 10.1093/glycob/4.1.49
  72. 10.1021/j100052a007
  73. 10.1007/BF02192812
  74. 10.1016/0003-9861(83)90128-5
  75. 10.1139/v80-098
  76. 10.1021/bk-1979-0087.ch002
  77. 10.1021/ja00381a009
  78. 10.1021/ja970960u
  79. 10.1021/ja954344e
  80. 10.1021/cr940413g
  81. 10.1021/ja970798v
  82. 10.1016/S0167-4838(97)00182-9
  83. 10.1074/jbc.272.9.5533
  84. 10.1007/BF00190452
  85. 10.1002/pro.5560030202
  86. 10.1021/bi00144a009
  87. 10.1093/glycob/8.2.147
  88. 10.1093/glycob/8.2.173
  89. 10.1006/jmrb.1995.1129
  90. 10.1016/0008-6215(88)80004-1
  91. 10.1016/S0301-0104(97)00265-6
  92. {'key': 'b92', 'volume-title': 'The Nuclear Overhauser Effect in Structural and Conformational Analysis.', 'author': 'Neuhaus D', 'year': '1989'} / The Nuclear Overhauser Effect in Structural and Conformational Analysis. by Neuhaus D (1989)
  93. 10.1021/bi962564e
  94. 10.1016/0079-6565(94)80015-4
  95. 10.1016/S1074-5521(96)90106-4
  96. 10.1021/bi971828+
  97. 10.1093/protein/4.4.427
  98. 10.1002/(SICI)1096-987X(199606)17:8<1068::AID-JCC14>3.3.CO;2-T
  99. 10.1016/0008-6215(95)00320-7
  100. 10.1002/jemt.1060110407
  101. Pérez S, Meyer C, Imberty A. 1995. Practical tools for accurate modeling of complex carbohydrates and their interactions with proteins. InModelling of Biomolecular Structures and Mechanisms, ed. A Pullman, J Jortner, B Pullman, pp. 425–54. Dordrecht, Netherlands: Kluwer (10.1007/978-94-011-0497-5_33)
  102. 10.1093/glycob/6.5.537
  103. 10.1016/0008-6215(93)87005-D
  104. 10.1016/S0959-440X(96)80039-X
  105. 10.1021/ja9610702
  106. 10.1021/ja00001a055
  107. {'key': 'b107', 'first-page': '636', 'volume': '92', 'author': 'Poppe L', 'year': '1991', 'journal-title': 'J. Magn. Reson.'} / J. Magn. Reson. by Poppe L (1991)
  108. {'key': 'b108', 'first-page': '214', 'volume': '93', 'author': 'Poppe L', 'year': '1991', 'journal-title': 'J. Magn. Reson.'} / J. Magn. Reson. by Poppe L (1991)
  109. 10.1021/ja00029a051
  110. 10.1038/nsb0494-215
  111. 10.1016/S1093-3263(97)00012-0
  112. 10.1016/S0008-6215(97)00034-7
  113. 10.1023/A:1018395627017
  114. 10.1023/A:1006909515343
  115. 10.1128/iai.65.9.3713-3718.1997 / Infect. Immun. by Powell JL (1997)
  116. 10.1002/bip.360241205
  117. 10.1002/(SICI)1096-987X(199603)17:4<450::AID-JCC6>3.3.CO;2-R
  118. 10.1021/bi00241a003
  119. 10.1016/0959-440X(93)90048-P
  120. 10.1146/annurev.bb.24.060195.003003
  121. 10.1021/bi00210a021
  122. 10.1021/ja00006a019
  123. 10.1039/a708550h
  124. 10.1021/bi00155a013
  125. 10.1023/A:1018358929268
  126. 10.1002/anie.199518411
  127. 10.1016/0141-8130(84)90020-5
  128. 10.1021/jo9612483
  129. 10.1126/science.2552581
  130. 10.1093/emboj/16.16.5139
  131. 10.1139/v82-009
  132. 10.1126/science.278.5340.1111
  133. 10.1021/jm9606103
  134. 10.1016/0008-6215(89)84112-6
  135. 10.1126/science.8211161
  136. 10.1016/S0959-440X(94)90168-6
  137. 10.1016/0955-0674(92)90041-A
  138. 10.1016/0008-6215(79)80002-6
  139. 10.1021/bi00041a049
  140. 10.1023/A:1006984709892
  141. {'key': 'b141', 'first-page': '3832', 'volume': '99', 'author': 'Woods RJ', 'year': '1995', 'journal-title': 'J. Am. Chem. Soc.'} / J. Am. Chem. Soc. by Woods RJ (1995)
  142. 10.1016/S0969-2126(96)00141-4
  143. 10.1021/bi961262+
  144. 10.1021/bi961261h
  145. 10.1016/S0008-6215(97)10099-4
  146. 10.1093/glycob/6.3.281
  147. 10.1002/(SICI)1097-0282(199603)38:3<339::AID-BIP7>3.3.CO;2-L
  148. 10.1006/jmbi.1997.1407
  149. 10.1073/pnas.91.14.6423
  150. 10.1021/jp963956y
Dates
Type When
Created 23 years, 1 month ago (July 27, 2002, 7:42 a.m.)
Deposited 3 years, 10 months ago (Oct. 6, 2021, 5:12 p.m.)
Indexed 4 weeks, 2 days ago (Aug. 7, 2025, 4:52 a.m.)
Issued 26 years, 3 months ago (June 1, 1999)
Published 26 years, 3 months ago (June 1, 1999)
Published Print 26 years, 3 months ago (June 1, 1999)
Funders 0

None

@article{Bush_1999, title={STRUCTURE AND CONFORMATION OF COMPLEX CARBOHYDRATES OF GLYCOPROTEINS, GLYCOLIPIDS, AND BACTERIAL POLYSACCHARIDES}, volume={28}, ISSN={1545-4266}, url={http://dx.doi.org/10.1146/annurev.biophys.28.1.269}, DOI={10.1146/annurev.biophys.28.1.269}, number={1}, journal={Annual Review of Biophysics and Biomolecular Structure}, publisher={Annual Reviews}, author={Bush, C. Allen and Martin-Pastor, Manuel and Imbery, Anne}, year={1999}, month=jun, pages={269–293} }