DOI: 10.1146/annurev.bioeng.10.061807.160431. Fluorescence Imaging of Membrane Dynamics

Fluorescence Imaging of Membrane Dynamics

10.1146/annurev.bioeng.10.061807.160431

Crossref journal-article

Annual Reviews

Annual Review of Biomedical Engineering (22)

Abstract

Imaging membrane dynamics is an important goal, motivated by the abundance of biochemical and biophysical events that are orchestrated at, or by, cellular membranes. The short length scales, fast timescales, and environmental requirements of membrane phenomena present challenges to imaging experiments. Several technical advances offer means to overcome these challenges, and we describe here three powerful techniques applicable to membrane imaging: total internal reflection fluorescence (TIRF) microscopy, fluorescence interference contrast (FLIC) microscopy, and fluorescence correlation spectroscopy (FCS). For each, we discuss the physics underpinning the approach, its practical implementation, and recent examples highlighting its achievements in exploring the membrane environment.

Bibliography

Groves, J. T., Parthasarathy, R., & Forstner, M. B. (2008). Fluorescence Imaging of Membrane Dynamics. Annual Review of Biomedical Engineering, 10(1), 311â338.

Authors 3

Jay T. Groves (first)
Raghuveer Parthasarathy (additional)
Martin B. Forstner (additional)

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Dates

Type	When
Created	17 years, 4 months ago (April 22, 2008, 4:46 p.m.)
Deposited	1 year, 6 months ago (Feb. 25, 2024, 5:36 a.m.)
Indexed	3 weeks, 2 days ago (Aug. 7, 2025, 5:19 p.m.)
Issued	17 years ago (Aug. 1, 2008)
Published	17 years ago (Aug. 1, 2008)
Published Print	17 years ago (Aug. 1, 2008)

Funders 0

None

BibTeX

@article{Groves_2008, title={Fluorescence Imaging of Membrane Dynamics}, volume={10}, ISSN={1545-4274}, url={http://dx.doi.org/10.1146/annurev.bioeng.10.061807.160431}, DOI={10.1146/annurev.bioeng.10.061807.160431}, number={1}, journal={Annual Review of Biomedical Engineering}, publisher={Annual Reviews}, author={Groves, Jay T. and Parthasarathy, Raghuveer and Forstner, Martin B.}, year={2008}, month=aug, pages={311–338} }

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