Proton-Coupled Electron Transfer in Biology: Results from Synergistic Studies in Natural and Model Systems
10.1146/annurev.biochem.78.080207.092132
Crossref journal-article
Annual Reviews
Annual Review of Biochemistry (22)
Abstract

Proton-coupled electron transfer (PCET) underpins energy conversion in biology. PCET may occur with the unidirectional or bidirectional transfer of a proton and electron and may proceed synchronously or asynchronously. To illustrate the role of PCET in biology, this review presents complementary biological and model systems that explore PCET in electron transfer (ET) through hydrogen bonds [azurin as compared to donor-acceptor (D-A) hydrogen-bonded networks], the activation of C–H bonds [alcohol dehydrogenase and soybean lipoxygenase (SLO) as compared to Fe(III) metal complexes], and the generation and transport of amino acid radicals [photosystem II (PSII) and ribonucleotide reductase (RNR) as compared to tyrosine-modified photoactive Re(I) and Ru(II) complexes]. In providing these comparisons, the fundamental principles of PCET in biology are illustrated in a tangible way.

Bibliography

Reece, S. Y., & Nocera, D. G. (2009). Proton-Coupled Electron Transfer in Biology: Results from Synergistic Studies in Natural and Model Systems. Annual Review of Biochemistry, 78(1), 673–699.

Authors 2
  1. Steven Y. Reece (first)
  2. Daniel G. Nocera (additional)
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Dates
Type When
Created 16 years, 4 months ago (April 3, 2009, 10:41 a.m.)
Deposited 3 years, 10 months ago (Oct. 5, 2021, 8:18 a.m.)
Indexed 6 hours, 7 minutes ago (Aug. 30, 2025, 1:05 p.m.)
Issued 16 years, 2 months ago (June 1, 2009)
Published 16 years, 2 months ago (June 1, 2009)
Published Print 16 years, 2 months ago (June 1, 2009)
Funders 0

None

@article{Reece_2009, title={Proton-Coupled Electron Transfer in Biology: Results from Synergistic Studies in Natural and Model Systems}, volume={78}, ISSN={1545-4509}, url={http://dx.doi.org/10.1146/annurev.biochem.78.080207.092132}, DOI={10.1146/annurev.biochem.78.080207.092132}, number={1}, journal={Annual Review of Biochemistry}, publisher={Annual Reviews}, author={Reece, Steven Y. and Nocera, Daniel G.}, year={2009}, month=jun, pages={673–699} }