DOI: 10.1146/annurev-micro-102215-095630. Bacterial Membranes: Structure, Domains, and Function

Bacterial Membranes: Structure, Domains, and Function
10.1146/annurev-micro-102215-095630
Crossref journal-article
Annual Reviews
Annual Review of Microbiology (22)
Abstract
The bacterial cytoplasmic membrane is composed of roughly equal proportions of lipids and proteins. The main lipid components are phospholipids, which vary in acyl chain length, saturation, and branching and carry head groups that vary in size and charge. Phospholipid variants determine membrane properties such as fluidity and charge that in turn modulate interactions with membrane-associated proteins. We summarize recent advances in understanding bacterial membrane structure and function, focusing particularly on the possible existence and significance of specialized membrane domains. We review the role of membrane curvature as a spatial cue for recruitment and regulation of proteins involved in morphogenic functions, especially elongation and division. Finally, we examine the role of the membrane, especially regulation of synthesis and fluid properties, in the life cycle of cell wall–deficient L-form bacteria.
Bibliography
Strahl, H., & Errington, J. (2017). Bacterial Membranes: Structure, Domains, and Function. Annual Review of Microbiology, 71(1), 519â538.
Authors 2
Henrik Strahl (first)
Jeff Errington (additional)
References 151 Referenced 254
Dates
Type	When
Created	8 years, 1 month ago (July 12, 2017, 12:34 a.m.)
Deposited	1 year, 2 months ago (June 25, 2024, 7:24 a.m.)
Indexed	9 minutes ago (Aug. 25, 2025, 8:54 p.m.)
Issued	7 years, 11 months ago (Sept. 8, 2017)
Published	7 years, 11 months ago (Sept. 8, 2017)
Published Print	7 years, 11 months ago (Sept. 8, 2017)
Funders 0
None
BibTeX
@article{Strahl_2017, title={Bacterial Membranes: Structure, Domains, and Function}, volume={71}, ISSN={1545-3251}, url={http://dx.doi.org/10.1146/annurev-micro-102215-095630}, DOI={10.1146/annurev-micro-102215-095630}, number={1}, journal={Annual Review of Microbiology}, publisher={Annual Reviews}, author={Strahl, Henrik and Errington, Jeff}, year={2017}, month=sep, pages={519–538} }
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  "abstract": "<jats:p>The bacterial cytoplasmic membrane is composed of roughly equal proportions of lipids and proteins. The main lipid components are phospholipids, which vary in acyl chain length, saturation, and branching and carry head groups that vary in size and charge. Phospholipid variants determine membrane properties such as fluidity and charge that in turn modulate interactions with membrane-associated proteins. We summarize recent advances in understanding bacterial membrane structure and function, focusing particularly on the possible existence and significance of specialized membrane domains. We review the role of membrane curvature as a spatial cue for recruitment and regulation of proteins involved in morphogenic functions, especially elongation and division. Finally, we examine the role of the membrane, especially regulation of synthesis and fluid properties, in the life cycle of cell wall\u2013deficient L-form bacteria.</jats:p>",
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