10.1146/annurev-matsci-062910-095803
Crossref journal-article
Annual Reviews
Annual Review of Materials Research (22)
Abstract

A crystallization pathway describes the movement of ions from their source to the final product. Cells are intimately involved in biological crystallization pathways. In many pathways the cells utilize a unique strategy: They temporarily concentrate ions in intracellular membrane-bound vesicles in the form of a highly disordered solid phase. This phase is then transported to the final mineralization site, where it is destabilized and crystallizes. We present four case studies, each of which demonstrates specific aspects of biological crystallization pathways: seawater uptake by foraminifera, calcite spicule formation by sea urchin larvae, goethite formation in the teeth of limpets, and guanine crystal formation in fish skin and spider cuticles. Three representative crystallization pathways are described, and aspects of the different stages of crystallization are discussed. An in-depth understanding of these complex processes can lead to new ideas for synthetic crystallization processes of interest to materials science.

Bibliography

Weiner, S., & Addadi, L. (2011). Crystallization Pathways in Biomineralization. Annual Review of Materials Research, 41(1), 21–40.

Authors 2
  1. Steve Weiner (first)
  2. Lia Addadi (additional)
References 87 Referenced 478
  1. {'key': 'B1', 'volume-title': 'Kinetic Theory of Liquids', 'author': 'Frenkel J.', 'year': '1946'} / Kinetic Theory of Liquids by Frenkel J. (1946)
  2. 10.1002/anie.199201531
  3. {'key': 'B3', 'first-page': '35', 'volume-title': 'Biomineralization: Chemical and Biochemical Perspectives', 'author': 'Mann S.', 'year': '1989'} / Biomineralization: Chemical and Biochemical Perspectives by Mann S. (1989)
  4. 4. Simkiss K, Wilbur K. 1989. Biomineralization. Cell Biology and Mineral Deposition. San Diego: Academic. 337 pp.
  5. 10.2113/0540057
  6. 10.1016/0968-0004(91)90098-G
  7. 10.1039/ft9938902891
  8. 10.1021/ja9628821
  9. 10.1038/331546a0
  10. 10. Lowenstam HA, Weiner S. 1989. On Biomineralization. New York: Oxford Univ. Press. 324 pp. (10.1093/oso/9780195049770.001.0001)
  11. 10.1021/ja00312a070
  12. 10.1107/S0365110X55000121
  13. 10.1039/a604512j
  14. 10.1098/rspb.1997.0066
  15. {'key': 'B15', 'volume-title': 'The Elementary Chemical Composition of Marine Organisms', 'author': 'Vinogradov AP.', 'year': '1953'} / The Elementary Chemical Composition of Marine Organisms by Vinogradov AP. (1953)
  16. 10.1016/S0022-5320(67)80015-7
  17. 10.1126/science.227.4682.51
  18. 10.1016/j.jinorgbio.2005.10.005
  19. 10.1002/adma.200300381
  20. 10.1126/science.1114920
  21. 10.1002/jmor.10311
  22. 10.1016/j.jsb.2008.02.007
  23. 10.1002/jez.90004
  24. 10.1002/1521-3765(20001016)6:20<3679::AID-CHEM3679>3.0.CO;2-#
  25. 10.1016/j.jsb.2009.02.001
  26. 10.1073/pnas.0914218107
  27. 10.1179/095066003225005836
  28. 10.1016/0025-5408(74)90087-7
  29. 10.1002/adfm.200600134
  30. 10.2113/0540115
  31. 10.1126/science.7008198
  32. 10.2307/1485304
  33. {'key': 'B33', 'first-page': '237', 'volume-title': 'Biomineralization in Plants and Lower Animals', 'author': 'Hemleben C', 'year': '1986'} / Biomineralization in Plants and Lower Animals by Hemleben C (1986)
  34. 10.1007/0-306-48104-9_15
  35. 10.1130/G21800.1
  36. 10.1073/pnas.0906636106
  37. 10.1073/pnas.0904306106
  38. 10.1029/2005GC001015
  39. 10.1002/(SICI)1521-4095(200001)12:1<38::AID-ADMA38>3.0.CO;2-I
  40. 10.1002/9783527619443.ch11
  41. 10.1006/jsbi.1999.4105
  42. 10.1111/j.1440-169X.1962.tb00156.x
  43. 10.1126/science.259.5096.776
  44. {'key': 'B44', 'first-page': '159', 'volume-title': 'Mechanisms of Biomineralization in Animals and Plants', 'author': 'Okazaki K', 'year': '1980'} / Mechanisms of Biomineralization in Animals and Plants by Okazaki K (1980)
  45. 10.1006/jsbi.1998.4081
  46. 10.1073/pnas.0806604105
  47. 10.1002/adfm.200304285
  48. 10.1126/science.1102289
  49. 10.1039/b704418f
  50. 10.1116/1.2354575
  51. 10.1016/0012-821X(79)90168-7
  52. 10.1016/j.jsb.2007.01.001
  53. 10.1126/science.171.3970.487
  54. 10.1021/cg050171l
  55. 10.1016/j.jcis.2003.10.032
  56. 10.1098/rspb.1987.0056
  57. 10.1098/rspb.1994.0168
  58. 10.1002/chem.19950010705
  59. 10.1002/1521-3765(20010504)7:9<1881::AID-CHEM1881>3.0.CO;2-I
  60. 10.1006/jsbi.2001.4372
  61. 10.1016/j.jsb.2008.01.008
  62. 10.1242/jeb.201.9.1307 / J. Exp. Biol. by Parker AR (1998)
  63. 10.1002/adfm.200901437
  64. 10.1146/annurev.ento.43.1.619
  65. 10.1021/cg0704753
  66. {'key': 'B66', 'first-page': '75', 'volume-title': 'Comparative Animal Physiology', 'author': 'Ladd Prosser C', 'year': '1950'} / Comparative Animal Physiology by Ladd Prosser C (1950)
  67. 10.1126/science.1164271
  68. 10.1126/science.1169434
  69. 10.1105/tpc.11.4.691
  70. 10.1007/978-3-662-06278-4_2
  71. 10.1111/j.1469-185X.1982.tb00375.x
  72. 10.2741/1576
  73. 10.1074/jbc.272.7.4404
  74. 10.1042/bst0140549
  75. 10.1083/jcb.56.3.838
  76. 10.1016/S0021-9258(17)37997-8 / J. Biol. Chem. by Dimuzio MT (1978)
  77. 10.1016/j.jsb.2005.09.009
  78. 10.1515/zpch-1897-2233 / Z. Phys. Chem. by Ostwald W. (1897)
  79. 10.1073/pnas.0502577102
  80. 10.1098/rstb.1984.0041
  81. 10.1002/anie.200601871
  82. 10.1002/jmor.10311
  83. 10.1515/9781400849505 / Bones by Currey J. (2002)
  84. 10.1016/j.bone.2006.02.059
  85. 10.1073/pnas.0803354105
  86. 10.1016/j.mser.2007.05.001
  87. 10.1038/35090573
Dates
Type When
Created 14 years, 5 months ago (March 1, 2011, 8:54 p.m.)
Deposited 3 years, 10 months ago (Oct. 13, 2021, 5:17 p.m.)
Indexed 1 day, 20 hours ago (Aug. 19, 2025, 6:59 a.m.)
Issued 14 years ago (Aug. 4, 2011)
Published 14 years ago (Aug. 4, 2011)
Published Print 14 years ago (Aug. 4, 2011)
Funders 0

None

@article{Weiner_2011, title={Crystallization Pathways in Biomineralization}, volume={41}, ISSN={1545-4118}, url={http://dx.doi.org/10.1146/annurev-matsci-062910-095803}, DOI={10.1146/annurev-matsci-062910-095803}, number={1}, journal={Annual Review of Materials Research}, publisher={Annual Reviews}, author={Weiner, Steve and Addadi, Lia}, year={2011}, month=aug, pages={21–40} }