Abstract
We succeeded in obtaining high-resolution images of a cell surface using a tapping-mode atomic force microscope (tapping-mode AFM) in air. The resulting images resolved many particles of 40-80 nm in radius and distinguished regions where the particles formed clusters from other regions. Such images could not be obtained using a contact-mode atomic force microscope (contact-mode AFM) operated under the same conditions. The result demonstrates the possibility of cell surface research using the tapping-mode AFM with molecular resolution.
References
37
Referenced
39
10.1103/PhysRevLett.56.930
/ Phys. Rev. Lett. (1986)10.1021/bi00116a005
/ Biochemistry (1992)10.1126/science.256.5060.1180
/ Science (1992)10.1093/nar/20.14.3585
/ Nucleic Acids Res. (1992)10.1093/nar/20.15.3983
/ Nucleic Acids Res. (1992)10.1093/nar/21.5.1117
/ Nucleic Acids Res. (1993)10.1093/nar/21.3.505
/ Nucleic Acids Res. (1993)10.1016/S0006-3495(93)81451-6
/ Biophys. J. (1993)10.1073/pnas.90.6.2137
/ Proc. Natl. Acad. Sci. USA (1993)10.1073/pnas.90.8.3598
/ Proc. Natl. Acad. Sci. USA (1993)10.1073/pnas.90.9.3811
/ Proc. Natl. Acad. USA (1993)10.1126/science.8503010
/ Science (1993)10.1126/science.2928794
/ Science (1989)10.1021/la00092a036
/ Langmuir (1990)10.1016/S0006-3495(90)82489-9
/ Biophys. J. (1990)10.1016/S0006-3495(90)82465-6
/ Biophys. J. (1990)10.1016/0014-5793(91)80298-H
/ FEBS Lett. (1991)10.1038/358171a0
/ Nature (1992)10.1016/0304-3991(92)90420-O
/ Ultramicroscopy (1992)10.1016/S0006-3495(93)81452-8
/ Biophys. J. (1993)10.1016/0014-5793(93)81756-P
/ FEBS Lett. (1993)10.1143/JJAP.32.2962
/ Jpn. J. Appl. Phys. (1993)10.1016/S0006-3495(90)82492-9
/ Biophys. J. (1990)10.1116/1.576398
/ J. Vac. Sci. & Technol. (1990)10.1016/0304-3991(92)90412-D
/ Ultramicroscopy (1992)10.1016/0304-3991(92)90414-F
/ Ultramicroscopy (1992)10.1016/S0006-3495(92)81719-8
/ Biophys. J. (1992)10.1016/1047-8477(90)90098-W
/ J. Structural Biol. (1990)10.1016/0304-3991(92)90418-J
/ Ultramicrosopy (1992)10.1126/science.1411505
/ Science (1992)10.1126/science.1411511
/ Science (1992)10.1016/0962-8924(92)90248-L
/ Trends Cell Biol. (1992)10.1016/S0006-3495(93)81396-1
/ Biophys. J. (1993)10.1242/jcs.104.2.427
/ J. Cell Sci. (1993)10.1016/S0006-3495(93)81493-0
/ Biophys. J. (1993)10.1016/0304-3991(93)90180-6
/ Ultramicroscopy (1993)10.1016/S0006-3495(91)82180-4
/ Biophys. J. (1991)
Dates
Type | When |
---|---|
Created | 20 years, 6 months ago (Feb. 22, 2005, 9:31 p.m.) |
Deposited | 2 years, 8 months ago (Dec. 6, 2022, 7:16 p.m.) |
Indexed | 2 months, 2 weeks ago (June 16, 2025, 8:08 a.m.) |
Issued | 31 years, 10 months ago (Nov. 1, 1993) |
Published | 31 years, 10 months ago (Nov. 1, 1993) |
Published Print | 31 years, 10 months ago (Nov. 1, 1993) |
@article{Umemura_1993, title={High Resolution Images of Cell Surface Using a Tapping-Mode Atomic Force Microscope}, volume={32}, ISSN={1347-4065}, url={http://dx.doi.org/10.1143/jjap.32.l1711}, DOI={10.1143/jjap.32.l1711}, number={11B}, journal={Japanese Journal of Applied Physics}, publisher={IOP Publishing}, author={Umemura, Kazuo and Hideo Arakawa, Hideo Arakawa and Atsushi Ikai, Atsushi Ikai}, year={1993}, month=nov, pages={L1711} }