DOI: 10.1139/o64-072. POLYSACCHARIDE-PEPTIDE COMPLEXES FROM SERRATIA MARCESCENS CELLS

POLYSACCHARIDE-PEPTIDE COMPLEXES FROM SERRATIA MARCESCENS CELLS

10.1139/o64-072

Crossref journal-article

Canadian Science Publishing

Canadian Journal of Biochemistry (155)

Abstract

Determinations were made of the chemical composition and antitumor properties of several polysaccharide fractions obtained by high speed centrifugation of aqueous extracts of the cells of Serratia marcescens following phenol extraction and trypsin digestion. The use of methods that ensured complete removal of lipid gave polysaccharides containing firmly bound amino acid residues. These were highly effective in causing complete regression of well established solid tumors in mice. The products derived primarily from the cell wall were more potent than the polysaccharides of extracellular and cytoplasmic origins. Extensive differences were also noted in the chemical composition of the polysaccharide complexes isolated from the two sources.

Bibliography

Creech, H. J., Breuninger, E. R., & Adams, G. A. (1964). POLYSACCHARIDE-PEPTIDE COMPLEXES FROM SERRATIA MARCESCENS CELLS. Canadian Journal of Biochemistry, 42(5), 593â603.

Authors 3

Hugh J. Creech (first)
Evelyn R. Breuninger (additional)
G. A. Adams (additional)

References 27 Referenced 20

{'key': 'p_1/p_1_1', 'first-page': '107', 'volume': '4', 'author': 'HARTWELL M. J.', 'journal-title': 'JR. J. Satl. Cancer Inst.'} / JR. J. Satl. Cancer Inst. by HARTWELL M. J.
{'key': 'p_2/p_2_1', 'first-page': '1109', 'volume': '14', 'author': 'RATHGEB B.', 'year': '1954', 'journal-title': 'SYLVEN. J. Natl. Cancer Inst.'} / SYLVEN. J. Natl. Cancer Inst. by RATHGEB B. (1954)
10.1128/JB.85.2.427-435.1963 / J. Bacteriol. by NOWOTNY. (1963)
{'key': 'p_4/p_4_1', 'first-page': '271', 'volume': '15', 'author': 'DAVIES.', 'year': '1960', 'journal-title': 'Advan. Carbohydrate Chem.'} / Advan. Carbohydrate Chem. by DAVIES. (1960)
{'key': 'p_6/p_6_1', 'first-page': '1195', 'volume': '14', 'author': 'IKAWA J. B.', 'year': '1954', 'journal-title': 'NIEMANN. J. Natl. Cancer Inst.'} / NIEMANN. J. Natl. Cancer Inst. by IKAWA J. B. (1954)
{'key': 'p_7/p_7_1', 'first-page': '1109', 'volume': '14', 'author': 'RATHGEB B.', 'year': '1954', 'journal-title': 'SYLVEN. J. Natl. Cancer Inst.'} / SYLVEN. J. Natl. Cancer Inst. by RATHGEB B. (1954)
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{'key': 'p_9/p_9_1', 'first-page': '824', 'volume': '14', 'author': 'CREECH R. F.', 'year': '1954', 'journal-title': 'HANKWITZ. Cancer Res.'} / HANKWITZ. Cancer Res. by CREECH R. F. (1954)
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Dates

Type	When
Created	15 years, 8 months ago (Dec. 17, 2009, 4:48 p.m.)
Deposited	1 year, 5 months ago (March 18, 2024, 4:54 a.m.)
Indexed	1 year, 5 months ago (March 18, 2024, 5:10 a.m.)
Issued	61 years, 4 months ago (May 1, 1964)
Published	61 years, 4 months ago (May 1, 1964)
Published Print	61 years, 4 months ago (May 1, 1964)

Funders 0

None

BibTeX

@article{Creech_1964, title={POLYSACCHARIDE-PEPTIDE COMPLEXES FROM SERRATIA MARCESCENS CELLS}, volume={42}, ISSN={0008-4018}, url={http://dx.doi.org/10.1139/o64-072}, DOI={10.1139/o64-072}, number={5}, journal={Canadian Journal of Biochemistry}, publisher={Canadian Science Publishing}, author={Creech, Hugh J. and Breuninger, Evelyn R. and Adams, G. A.}, year={1964}, month=may, pages={593–603} }

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