Abstract
To investigate the roles of bases near the tips of each strand of the long terminal repeat of the human immunodeficiency virus type 1 in the integration reaction, we examined the efficiencies of both binding and integration activities of staggered-ended substrates and mismatched mutant substrates by the integration assay and the UV cross-linking assay. Our results suggest that some bases of the human immunodeficiency virus type 1 long terminal repeat are required primarily for binding, whereas others are more critical for later reaction steps in vitro.
Dates
Type | When |
---|---|
Created | 5 years, 7 months ago (Jan. 6, 2020, 4:31 p.m.) |
Deposited | 3 years, 5 months ago (March 5, 2022, 8:11 a.m.) |
Indexed | 1 year, 7 months ago (Jan. 27, 2024, 5:17 a.m.) |
Issued | 30 years, 3 months ago (May 1, 1995) |
Published | 30 years, 3 months ago (May 1, 1995) |
Published Print | 30 years, 3 months ago (May 1, 1995) |
@article{Yoshinaga_1995, title={Different roles of bases within the integration signal sequence of human immunodeficiency virus type 1 in vitro}, volume={69}, ISSN={1098-5514}, url={http://dx.doi.org/10.1128/jvi.69.5.3233-3236.1995}, DOI={10.1128/jvi.69.5.3233-3236.1995}, number={5}, journal={Journal of Virology}, publisher={American Society for Microbiology}, author={Yoshinaga, T and Fujiwara, T}, year={1995}, month=may, pages={3233–3236} }