DOI: 10.1128/jvi.66.8.5133-5136.1992. Epstein-Barr virus-encoded small RNAs (EBERs) do not modulate interferon effects in infected lymphocytes

Epstein-Barr virus-encoded small RNAs (EBERs) do not modulate interferon effects in infected lymphocytes

10.1128/jvi.66.8.5133-5136.1992

Crossref journal-article

American Society for Microbiology

Journal of Virology (235)

Abstract

The recent derivation of otherwise isogenic Epstein-Barr virus (EBV) recombinants carrying or lacking the EBV small RNA (EBER) genes enabled us to test whether EBERs are similar to adenovirus VA RNAs in modulating interferon (IFN) effects on virus infection. EBER-positive and -negative EBV recombinants did not differ in their sensitivity to alpha interferon (IFN-alpha)- or IFN-gamma-mediated inhibition of lymphocyte growth transformation. In addition, EBERs did not decrease the inhibitory effects of IFN on vesicular stomatitis virus replication in EBV-transformed lymphocytes. EBER deletion also did not render EBV-transformed B lymphocytes susceptible to an IFN effect on cell proliferation or EBV replication.

Bibliography

Swaminathan, S., Huneycutt, B. S., Reiss, C. S., & Kieff, E. (1992). Epstein-Barr virus-encoded small RNAs (EBERs) do not modulate interferon effects in infected lymphocytes. Journal of Virology, 66(8), 5133â5136.

Authors 4

S Swaminathan (first)
B S Huneycutt (additional)
C S Reiss (additional)
E Kieff (additional)

References 0 Referenced 45

None

Dates

Type	When
Created	5 years, 7 months ago (Jan. 6, 2020, 11:26 a.m.)
Deposited	3 years, 5 months ago (March 4, 2022, 8:07 p.m.)
Indexed	5 months ago (March 27, 2025, 10:33 a.m.)
Issued	33 years, 1 month ago (Aug. 1, 1992)
Published	33 years, 1 month ago (Aug. 1, 1992)
Published Print	33 years, 1 month ago (Aug. 1, 1992)

Funders 0

None

BibTeX

@article{Swaminathan_1992, title={Epstein-Barr virus-encoded small RNAs (EBERs) do not modulate interferon effects in infected lymphocytes}, volume={66}, ISSN={1098-5514}, url={http://dx.doi.org/10.1128/jvi.66.8.5133-5136.1992}, DOI={10.1128/jvi.66.8.5133-5136.1992}, number={8}, journal={Journal of Virology}, publisher={American Society for Microbiology}, author={Swaminathan, S and Huneycutt, B S and Reiss, C S and Kieff, E}, year={1992}, month=aug, pages={5133–5136} }

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