DOI: 10.1128/jvi.44.2.493-498.1982. Effect of aphidicolin on avian sarcoma virus replication

Effect of aphidicolin on avian sarcoma virus replication

10.1128/jvi.44.2.493-498.1982

Crossref journal-article

American Society for Microbiology

Journal of Virology (235)

Abstract

We studied the effect of aphidicolin, an inhibitor of eucaryotic DNA polymerase alpha, on viral DNA replication and integration during the first 24 h after infection of quail embryo fibroblasts with avian sarcoma virus. In drug-treated cells, the synthesis of unintegrated linear viral DNA species was not impaired; however, the subsequent accumulation of circular viral DNA species and integrated proviral DNA was reversibly inhibited. After removal of the drug, circular viral DNA species were derived from preexisting linear viral DNA species, instead of being derived by de novo synthesis.

Bibliography

Hsu, T. W., & Taylor, J. M. (1982). Effect of aphidicolin on avian sarcoma virus replication. Journal of Virology, 44(2), 493â498.

Authors 2

T W Hsu (first)
J M Taylor (additional)

References 0 Referenced 18

None

Dates

Type	When
Created	5 years, 7 months ago (Jan. 5, 2020, 8:07 p.m.)
Deposited	3 years, 5 months ago (March 4, 2022, 5:46 p.m.)
Indexed	2 years, 5 months ago (March 31, 2023, 1:55 p.m.)
Issued	42 years, 10 months ago (Nov. 1, 1982)
Published	42 years, 10 months ago (Nov. 1, 1982)
Published Print	42 years, 10 months ago (Nov. 1, 1982)

Funders 0

None

BibTeX

@article{Hsu_1982, title={Effect of aphidicolin on avian sarcoma virus replication}, volume={44}, ISSN={1098-5514}, url={http://dx.doi.org/10.1128/jvi.44.2.493-498.1982}, DOI={10.1128/jvi.44.2.493-498.1982}, number={2}, journal={Journal of Virology}, publisher={American Society for Microbiology}, author={Hsu, T W and Taylor, J M}, year={1982}, month=nov, pages={493–498} }

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